Image_1_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_1_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_2_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_3_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_3_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_2_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

A genetic variant in human FIRE is associated with a decreased interferon response in myeloid cells. by Anaïs Assouvie (9600529)

Differences in abundance of lipid molecules in liver of <i>Fmo5</i>^<i>-/-</i> and WT mice. by Ian R. Phillips (5074121)

“…<p>(A) Volcano plot representation of lipid molecules (log₂-fold change) of <i>Fmo5</i>^<i>-/-</i> vs WT mice. …”

Image 5_G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo.tif by Nuzhat Rahman (16660416)

“…</p>Methods<p>Mice were inoculated with 10⁷ CFU of the eubiotic bacteria Lactobacillus crispatus, the dysbiotic bacteria G. vaginalis, or PBS as a negative control every 48 h for ten days. On day ten, mice were inoculated with 10⁵ PFU WT HSV-2 333 and survival, pathology, and viral titers were assessed. …”

Bacterial intracellular survival increases <i>in vivo</i> persistence in a mouse model of urinary tract infection and decreases antibiotic efficacy. by Cristina Penaranda (433703)

Nrf2 upregulates the transcription of 3 main target genes in response to SFN and zymosan. by Doumet Georges Helou (7255823)

S5 Fig - by Cynthia Alsayyah (18452506)

“…This indicates that inhibiting the entry of citrate into mitochondria induces the same effects as inhibiting the synthesis of peroxisomal citrate (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002602#pbio.3002602.g005" target="_blank">Fig 5E</a>). …”

Differences in abundance of non-lipid molecules in liver of <i>Fmo5</i>^<i>-/-</i> and WT mice. by Ian R. Phillips (5074121)

“…<p>(A) Volcano plot representation of non-lipid molecules (log₂-fold change) of <i>Fmo5</i>^<i>-/-</i> vs WT mice. …”

ALK^wt–ABT199 interactions. by Richard Junior Zapata Dongo (17912565)

Decreased activity of FASII favors the cold growth of the <i>ΔcshA</i> strain. by Vanessa Khemici (814639)

“…<i>fapR</i> mRNA levels were quantified by RT-qPCR using 16S rRNA as reference gene on total RNAs extracted from <i>wt</i> strain (PR01), <i>ΔcshA</i> strain (PR01-ΔcshA), and suppressor strains <i>ΔcshA/accC</i>^<i>M385V</i> (C51), <i>ΔcshA/accC</i>^<i>T183I</i> (sup30), <i>ΔcshA/accD</i>^<i>F253V</i> (sup17), <i>ΔcshA/accD</i>^<i>A164V</i> (sup16), <i>ΔcshA/birA</i>^{<i>D320F-FsX28</i>} (C58), <i>ΔcshA/birA</i>^{<i>R280stop</i>} (sup1) and <i>ΔcshA/bioY</i>^{<i>P123R-FsX1</i>} (C66), all at exponential growth phase in MH medium at 25°C. n = 5 for <i>ΔcshA</i>, <i>4 for wt</i> and 3 for all others. …”

The viability of human SH-SY5Y cells. by Tonglin Lu (6433043)

DGAT-1 Inhibitor A922500 decreases the pro-inflammatory profile and cell death induced by SARS-CoV-2 infection and reduces the viral load in human monocyte. by Suelen Silva Gomes Dias (9928813)

Immunostaining of lungs from a control mouse and a mouse infected with SARS-CoV-2. by Germán Ricardo Magaña-Ávila (18446799)

Summary of structural dynamics of WT and mutant RhoGAPs-RhoA complexes. by Zen Kouchi (14898435)

The parameters of gas exchange markedly decreased in maize <i>zmstomagen1/2</i> mutant compared with in wild type (WT). by Juan-Juan Xu (18590868)