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5 wt » _ wt (Expand Search), 5 ht (Expand Search)
point decrease » point increase (Expand Search)
ppm decrease » _ decrease (Expand Search), nn decrease (Expand Search), pa decreased (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), nn decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 point » _ point (Expand Search)
5 wt » _ wt (Expand Search), 5 ht (Expand Search)
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GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age.
Published 2021“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver.
Published 2021“…(A-B) GCase levels as assessed by the CBE/4-MU method are significantly decreased in the het <i>GBA1</i> D409V KI mice at 5 months of age in both brain (A) and liver (B). …”
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FLIM-FRET measurements with KIRIN1 sensor detects relative changes in intracellular K<sup>+</sup>.
Published 2024“…<b>(C)</b> FLIM-FRET measurements for intracellular K<sup>+</sup> levels in HEK293 Cells transfected with the CMV:KIRIN1 sensor and either CMV:Kcnk5bS345A-mCherry, CMV:Kcnk5bWT-mCherry, or CMV:Kcnk5bS345E-mCherry. …”