Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Simvastatin and benznidazole decreased cell adhesion molecule amount during <i>Trypanosoma cruzi</i> infection of endothelial cells. by Carolina Campos-Estrada (403914)

The novel <i>carboxylesterase 1</i> variant c.662A>G may decrease the bioactivation of oseltamivir in humans by Jaeseong Oh (3947381)

“…A novel <i>CES1</i> c.662A>G single nucleotide polymorphism (SNP) was predicted to decrease CES1 enzymatic activity in an <i>in silico</i> analysis. …”

Decreased pulmonary cell inflammatory response in FI-A2 and G-A2 peptide vaccinated mice after RSV challenge. by Gertrud U. Rey (501694)

<i>btuE</i> expression results in decreased intracellular ROS. by Felipe A. Arenas (23050)

(R)-albuterol decreases cytokine mRNA levels in activated T cells by Marcela A Ferrada (41716)

“…</p><p></p> (R)-albuterol, (S)-albuterol or racemic albuterol (R + S) at a dose (10M) were added to T (EL-4) cells pre-activated with mitogens Concanavalin A (Con A, 5 μg/ml) and phorbol myristate acetate (PMA, 100 ng/ml) (CP). …”

UGGT activity decreases in <i>uggt-1(RNAi)</i> worms but no decrease was observed in <i>uggt-2 (RNAi)</i> worms. by Lucila I. Buzzi (198284)

Ts5-immunization assay. by Felipe Cerni (3477902)

Fig 5 - by Samer Sawalha (5890535)

FXR decreases in mice livers with pathological injuries induced by <i>S</i>. <i>japonicum</i> infection. by Beibei Zhang (509356)

Taxonomic differences in Hg, Se and molar Hg:Se ratios (ppm, wet weight), shown in approximately decreasing values from top to bottom, according to statistically significant taxono... by Roxanne Karimi (453198)

Fig 5 - by Alireza Badirzadeh (4248763)

Fig 5 - by Hossein Azizian (17696750)

Annual mean energy for the individual wavelet components (thick coloured curves) and a linear model best-fit based on the annual global mean temperature (dashed lines), also estima... by Rasmus E. Benestad (12530330)

Levels of the antioxidant enzyme, MnSOD are decreased in the cortical and hippocampal microvessels. by Susan A. Austin (768265)

<i>Gnas</i> deletion in hypothalamic <i>Opn5</i> neurons. by Kevin D. Gaitonde (15411707)

Subjects:

PPM1A directly dephosphorylates STING and TBK1 and prevents STING aggregation. by Zexing Li (713843)

“…(D) PPM1A decreases phosphorylation of TBK1 in transfected HEK293 cells. …”

25OHD₃ increases expression of TRPV5 in the kidneys of CYP27B1^-/- mice with CKD. by Noelia Torremadé (3687523)

Decreased brain-derived neurotrophic factor plasma levels in psoriasis patients by A.R. Brunoni (5694239)

Antibody response elicited by SARS-CoV-2 vaccines. by Chris Davis (647632)