ML246 and voluntary exercise decrease cerebral amyloid plaques and ameliorate memory deficits in 5XFAD AD mice. by Altea Rocchi (3278457)

Positive modulation of mGluR5 decreases spine density in the nucleus accumbens but not in the dorsal striatum. by Kellie S. Gross (3115299)

“…<p>(A) Twenty-four hours after systemic administration, CDPPB (5–10 mg/kg, <i>n</i> = 18 animals) decreased dendritic spine density and frequency of small head diameter spines (0.2 μm bin) compared to vehicle control (<i>n</i> = 8) in the nucleus accumbens core. …”

Removal of the blue component of light significantly decreases retinal damage after high intensity exposure by Javier Vicente-Tejedor (4966858)

“…<div><p>Light causes damage to the retina (phototoxicity) and decreases photoreceptor responses to light. The most harmful component of visible light is the blue wavelength (400–500 nm). …”

Overexpression of ZnT3 and ZnT10 decreases ROS and prevents Ang II-induced senescence. by Nikolay Patrushev (179006)

Simulated response to Ach at activated NALCN channels and decreased phosphodiesterase (PDE) activity in low glucose. by Leonid E. Fridlyand (2636968)

“…<p>(A) PM potentials (V_p); (B) [Ca²⁺]_c and [Ca²⁺]_ER; (C) Cytoplasmic cAMP and IP₃ concentrations. …”

Alp5a and Alp5b are not individually required for asexual blood stage propagation, but simultaneously, they are indispensable for parasite viability. by Aastha Varshney (22601181)

“…<p><b>(A)</b> Parasites transfected with constructs targeting Alp5a and Alp5b, tagged with mCherry and GFP respectively, predominantly gave rise to single knockout populations expressing only one of the two fluorophores. …”

Ba₂NaClP₂O₇: Unprecedented Phase Matchability Induced by Symmetry Breaking and Its Unique Fresnoite-Type Structure by Jie Chen (5892)

“…Herein, we report a unique Ba₂NaClP₂O₇ representing the first phase-matchable example of the fresnoite family, which exhibits excellent NLO properties, including short absorption edge (<176 nm, ca. 7.0 eV), strong second-harmonic generations at the incident lasers of 850–1110 nm (obv. 0.9–1.3 × KDP; cal. …”

miR-214 decreased the number of viable cells and induced apoptosis in HSA cell lines. by Kazuki Heishima (791938)

“…<p>(A) Cell viability was assessed by performing the MTT assay. miR-214-transfection decreased the number of viable cells in HSA cell lines and that of control EC. …”

Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i>_i = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i>_i = 0.436 nM) substitution of the <i>N</i>⁴-benzyloxy group decreased <i>K</i>_i by ∼20-fold. …”

Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i>_i = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i>_i = 0.436 nM) substitution of the <i>N</i>⁴-benzyloxy group decreased <i>K</i>_i by ∼20-fold. …”

Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i>_i = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i>_i = 0.436 nM) substitution of the <i>N</i>⁴-benzyloxy group decreased <i>K</i>_i by ∼20-fold. …”

UV dose responses by sequential UV-A followed by UV-C exposure for (A) MS2 and (B) E. coli K-12 in PBS and NOM. by Daniel Ma (12698752)

Fe limitation decreases transcriptional regulation over the diel cycle in the model diatom <i>Thalassiosira pseudonana</i> - Fig 2 by Johanna A. L. Goldman (7372724)

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…SWATH methodology quantified 258 proteins (using ≥2 peptides) and 5 proteins (ALBU, ANXA6, HNRPK, HSP90A, and PDIA1) were differentially expressed (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). iTRAQ workflow identified 765 proteins; 354 proteins were quantified and 14 proteins (MIF, UBIQ, HXK3, ALBU, HNRPD, ST1A2, RS15A, RAP1B, CAN1, IQGA2, ST1A1, COX5A, ADDA, and UBQL1) were significantly different between the two groups of women (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). …”

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…SWATH methodology quantified 258 proteins (using ≥2 peptides) and 5 proteins (ALBU, ANXA6, HNRPK, HSP90A, and PDIA1) were differentially expressed (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). iTRAQ workflow identified 765 proteins; 354 proteins were quantified and 14 proteins (MIF, UBIQ, HXK3, ALBU, HNRPD, ST1A2, RS15A, RAP1B, CAN1, IQGA2, ST1A1, COX5A, ADDA, and UBQL1) were significantly different between the two groups of women (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). …”

Emission spectra of S100A1 fluorescence titrations exhibiting decreasing fluorescence intensities with increasing concentration of S100B at the μM level. by Md. Imran Khan (4853302)

Effect of exogenous ERα expression on the ability of Wnt-5a to decrease breast cancer cell invasion. by Janna Sand-Dejmek (449584)

Synthesis and Characterization of <i>meso</i>-Triarylsubporphyrins by Yuichi Takeuchi (189169)

Subjects:

Synthesis and Characterization of <i>meso</i>-Triarylsubporphyrins by Yuichi Takeuchi (189169)

Subjects:

R848 mediated RANTES, but not TNF-α production, is significantly decreased in TRAM^−/− iBMDMs. by Enda Shevlin (628477)