DataSheet_1_High expression of RARG accelerates ovarian cancer progression by regulating cell proliferation.zip by Lin Xiu (11085656)

“…The area under the curve (AUC) of RAGR expression for predicting patient survival rates at 1, 5 and 9 years were 0.659, 0.616 and 0.627, respectively. …”

Image_6_Autophagy-Related LC3 Accumulation Interacted Directly With LIR Containing RIPK1 and RIPK3, Stimulating Necroptosis in Hypoxic Cardiomyocytes.TIF by Yao Huang (216100)

“…Conversely, after alleviating hypoxia-induced autophagic flux impairment with LC3 or ATG5 knockdown adenovirus, the effects of hypoxia on RIPK1 and RIPK3 levels were reduced, which resulted in decreased p-RIPK3 and p-MLKL. …”

Is the risk of progressive multifocal leukoencephalopathy the real reason for natalizumab discontinuation in patients with multiple sclerosis? by Julia Krämer (436881)

“…Despite introduction of the currently employed PML risk stratification algorithm, the incidence of natalizumab-associated PML cases is not decreasing.</p><p>Objectives</p><p>We addressed the following questions: How do natalizumab-treated multiple sclerosis patients and their treating physicians assess and deal with PML risk? …”

Image_2_Autophagy-Related LC3 Accumulation Interacted Directly With LIR Containing RIPK1 and RIPK3, Stimulating Necroptosis in Hypoxic Cardiomyocytes.TIF by Yao Huang (216100)

“…Conversely, after alleviating hypoxia-induced autophagic flux impairment with LC3 or ATG5 knockdown adenovirus, the effects of hypoxia on RIPK1 and RIPK3 levels were reduced, which resulted in decreased p-RIPK3 and p-MLKL. …”

Complex interaction networks of cytokines after transarterial chemotherapy in patients with hepatocellular carcinoma by Dong Wook Jekarl (6851633)

“…After TACE, IL-1β, -6,-9, -12, and -22 increased by D60. IL-2, -5, -10, -17A and INF-γ decreased by D60, and IL-4, -13 and TNF-α revealed stable concentration. …”

Table_1_Optimized Parameters for Transducing the Locus Coeruleus Using Canine Adenovirus Type 2 (CAV2) Vector in Rats for Chemogenetic Modulation Research.DOCX by Latoya Stevens (10588391)

“…The most diluted conditions (Low volume_0.1E pp and Medium Volume_0.1E pp) presented similar high transduction of LC neurons (70.9 ± 12.7 and 77.2 ± 9.8%) with lower aspecificity (5.5 ± 3.5 and 4.0 ± 1.9%, respectively). Signs of toxicity were observed in all undiluted conditions as evidenced by a decreased size of the transduced LC.…”

Image1_Alteration in the number, morphology, function, and metabolism of erythrocytes in high-altitude polycythemia.TIF by Song Yu (3073554)

“…<p>Introduction: High-altitude polycythemia (HAPC) is a common chronic high-altitude disease characterized by significantly increased erythrocyte, hemoglobin (Hb), and hematocrit values and decreased arterial oxygen saturation. …”

Table2_Alteration in the number, morphology, function, and metabolism of erythrocytes in high-altitude polycythemia.DOCX by Song Yu (3073554)

“…<p>Introduction: High-altitude polycythemia (HAPC) is a common chronic high-altitude disease characterized by significantly increased erythrocyte, hemoglobin (Hb), and hematocrit values and decreased arterial oxygen saturation. …”

Table1_Alteration in the number, morphology, function, and metabolism of erythrocytes in high-altitude polycythemia.DOCX by Song Yu (3073554)

“…<p>Introduction: High-altitude polycythemia (HAPC) is a common chronic high-altitude disease characterized by significantly increased erythrocyte, hemoglobin (Hb), and hematocrit values and decreased arterial oxygen saturation. …”

Data Sheet 1_Amyloid-induced mitochondrial network disruption in neurons monitored by STED super-resolution imaging.pdf by Iuliia Golovynska (18880049)

“…As a result, the volume and surface area per mitochondrion decrease by 6-fold and 4-fold, respectively. …”

Summary of responses to free-flight antennal stimulation of extrinsic antennal muscles in six animals. by Armin J. Hinterwirth (109677)

“…In most cases, stimulation is associated with a decrease in ground speed. In cells labeled “n.a.”, parameters could not be computed because a full 3D path was impossible to reconstruct.…”

The cytoplasmic and extracellular domains are required for Sdc function. by Margaret U. Nguyen (3177789)

“…(C) Sdc mutants had a significant decrease in boutons per NMJ as described previously [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0151621#pone.0151621.ref005" target="_blank">5</a>]. …”

Extreme Evolutionary Disparities Seen in Positive Selection across Seven Complex Diseases by Erik Corona (171556)

“…We take a large set of the most strongly associated SNPs in each GWA study in order to capture more hidden associations at the cost of introducing false positives into our analysis. …”

Microgel-Based Stretchable Reservoir Devices for Elongation Enhanced Small Molecule Release Rate by Yingnan Zhang (270437)

“…Stretchable poly­(<i>N</i>-isopropylacrylamide)-<i>co</i>-acrylic acid (pNIPAm-<i>co</i>-10% AAc) microgel-based reservoir devices were fabricated and used to control the release rate of the small molecule model drug tris­(4-(dimethylamino)­phenyl)­methylium chloride (crystal violet, CV) to solution by varying the Au layer thickness coating the microgels and device elongation. Specifically, we showed that CV could be loaded into the microgel layer of the devices via electrostatic interactions at pH 6.5, and the release could be triggered upon exposure to a pH 3.0 solution, which breaks the microgel–CV electrostatic interactions. …”

Real-Time Changes in Corticospinal Excitability during Voluntary Contraction with Concurrent Electrical Stimulation by Tomofumi Yamaguchi (131732)

“…We monitored motor evoked potentials (MEPs) elicited by transcranial magnetic stimulation and recorded the MEPs using a mechanomyogram, which is less susceptible to electrical artifacts. …”

Microgel-Based Stretchable Reservoir Devices for Elongation Enhanced Small Molecule Release Rate by Yingnan Zhang (270437)

“…Stretchable poly­(<i>N</i>-isopropylacrylamide)-<i>co</i>-acrylic acid (pNIPAm-<i>co</i>-10% AAc) microgel-based reservoir devices were fabricated and used to control the release rate of the small molecule model drug tris­(4-(dimethylamino)­phenyl)­methylium chloride (crystal violet, CV) to solution by varying the Au layer thickness coating the microgels and device elongation. Specifically, we showed that CV could be loaded into the microgel layer of the devices via electrostatic interactions at pH 6.5, and the release could be triggered upon exposure to a pH 3.0 solution, which breaks the microgel–CV electrostatic interactions. …”

RHO-1 regulates fecundity. by Rachel McMullan (183027)

“…Expression of <i>hsRHO-1</i>(<i>G14V</i>) (<i>nzIs1</i>) or <i>nRHO-1</i>(<i>G14V</i>) (<i>nzIs29</i>) led to a significant decrease in the number of eggs remaining in animals when compared to wild type controls. …”

Effect of BCAS on myelin and inflammation in subcortical and cortical tissue. by Yun-An Lim (337762)

“…<p>(A-G) Analysis of the subcortical region. (A) Representative immunoblots of subcortical region 15D post BCAS (S = Sham, B+V = BCAS+Veh, B+A = BCAS+Ac-YVAD-cmk). …”

<em>Nigella sativa</em> (Black Cumin) Seed Extract Alleviates Symptoms of Allergic Diarrhea in Mice, Involving Opioid Receptors by Swantje C. Duncker (154707)

“…DAMGO, in contrast, had no effect on mast cell parameters but decreased IFNγ, IL-4, IL-5, and IL-10 concentration after <em>ex vivo</em> re-stimulation of mesenteric lymphocytes. …”

The GePPI screen identifies Elm1 as involved in the regulation of SBF by Cdc28. by Emily N. Manderson (272555)

“…Dark red indicates increase in PCA signal, dark blue indicates decrease in PCA signal, and black represents no change in PCA signal in a deletion strain relative to <i>MatA</i>. …”