Modulation by decitabine of gene expression and growth of osteosarcoma U2OS cells and in xenografts: Identification of apoptotic genes as targets for demethylation-4 by Khaldoun Al-Romaih (79731)

“…There was a significant decrease (p < 0.001) in methylation quantity for each CpG position after decitabine treatment both and for the four genes in all sample but not in the NHOst (normal human osteoblasts). p-values were calculated by comparing the percentage of methylation for each individual CpG position in control cells with the same CpG position in the treated cells using student t-test and they all resulted in p < 0.001.…”

Figure 1 from Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells by Stacia L. Koppenhafer (16616290)

“…<p>HDAC inhibitors decrease RRM1, RRM2, CHK1, and WEE1 protein levels. …”

Table_1_Effects of Urban Development Patterns on Municipal Water Shortage.DOCX by Hadi Heidari (9300375)

“…The future water supply is estimated using the Soil and Water Assessment Tool (SWAT) driven with a hot-dry climate model from the statistically downscaled Coupled Model Intercomparison Project, phase 5 (CMIP5) projections. …”

Notch and Wnt signaling-mediated activation of Müller cells in S334ter rats <i>in vivo</i>. by Carolina Beltrame Del Debbio (243080)

“…Q-PCR analysis of gene expression revealed increase in levels of transcripts corresponding to <i>Ki67</i>, <i>cyclinD1</i>, <i>Hes1</i>, <i>Hes5</i> and decrease in <i>p27^kip1</i> transcript levels in Jag1+Wnt2b treated retina, compared to controls (<b>H</b>). …”

Gene expression analysis of <i>Pten</i> mutant prostates. by Isabel B. Lokody (755298)

“…<p>(A) i) Heatmap demonstrating that control samples (C1-C5) show similar expression patterns to each other, as do mutant samples (M1-M5). ii) Genes chosen for validation are indicated in heatmap derived from the average of control and mutant samples. …”

Summary of phenotypic data of the candidate genes implicated in HR-DSBR. by Mikołaj Słabicki (246635)

“…Genes that after knockdown decreased the frequency of HR below z-score −4, −2, or −1.5 are marked with ↓↓↓, ↓↓ or ↓, respectively; genes that increase the frequency of HR over z-score 4, 2, or 1.5 are marked with ↑↑↑, ↑↑, or ↑, respectively; n.a., not available. …”

Waterfall plot showing the quantitative changes in ER, PR, and Ki-67 expression. by Yuqin Ding (623253)

“…(A) ER discordance rate: 10.4% (50/482) of patients, including 36 (7.5%) patients with positive-to-negative conversion and 14 (2.9%) patients with negative-to-positive conversion; (B) PR discordance rate: 17.0% (82/482) of patients, including 57 (11.8%) patients with positive-to-negative conversion and 25 (5.2%) patients with negative-to-positive conversion; (C) Ki-67 discordance rates: 50.4% (243/448) of patients had decreased expression and 27.0% (130/448) of patients had increased expression.…”

IL-1β depletion and IL-1 receptor antagonist treatment alleviated the neutrophilic inflammation. by Wen-Cheng Chao (2817868)

“…<p>The characteristic pulmonary histopathological images (A) of <i>M</i>. <i>marinum</i>-infected <i>Ncf1</i>^<i>-/-</i> mice and WT mice on day-5 with and without IL-1β depletion by a monoclonal antibody directed against IL-1β (150μg on day-1). …”

Adaptation period to diets with low or high fiber on digetibility and faecal characteristics in dogs by T. Ramos (7501706)

“…Fecal consistency of the dogs did not differ among diets and periods (P> 0.05). There was a decrease in fecal pH and ammonia in dogs fed the diet with 15% SH (P< 0.05) after 10 days of feeding (P< 0.05). …”

Distribution of estimated parameters by the three approaches with only 3 recorded responses. by Alireza Ghadimi (13839874)

“…The PDFs have been estimated from the results of applying each algorithm with 1000 different initial guesses. Moreover, a 5% white noise has been added to the reference data. …”

Supplementary Material for: Identification of risk factors associated with metabolic dysfunction-associated steatotic liver disease in psoriatic patients by Küçük K. (20178678)

“…We identified parameters which were more prevalent in patients with psoriasis having MASLD, specifically a high BMI, elevated triglycerides levels, decreased HDL levels and an elevate level of C-peptide. …”

DataSheet_1_Treatment Interruptions During Stereotactic Body Radiotherapy for Prostate Cancer.docx by Abigail N. Pepin (11966438)

“…Median length of time to complete treatment was 11 days (range 5–155 days). In patients who experienced a delay, nearly half (45.5%) experienced only a one-day delay. …”

Analysis of LPP levels and sub-cellular distribution in CD and controls fibroblasts before and after P31-43 treatment. by Merlin Nanayakkara (228892)

“…Focal adhesions of 30 fibroblasts from several fields from 3 independent experiments with 5 patients and 5 controls were counted. Columns represent the means, and the bars represent the standard deviations. …”

Image2_Arnica Montana L. Supercritical Extraction Optimization for Antibiotic and Anticancer Activity.JPEG by Taja Žitek (12521470)

“…The content of proanthocyanidins was highest at a pressure between 18 and 24 MPa. The extracts inhibited three different microorganisms successfully; Staphylococcus aureus, Escherichia coli and Candida albicans, at concentrations ranging from 0.1 to 5.16 mg/ml and showed anticancer activity decrease up to 85% at a concentration of 0.5 mg/ml.…”

Image1_Arnica Montana L. Supercritical Extraction Optimization for Antibiotic and Anticancer Activity.JPEG by Taja Žitek (12521470)

“…The content of proanthocyanidins was highest at a pressure between 18 and 24 MPa. The extracts inhibited three different microorganisms successfully; Staphylococcus aureus, Escherichia coli and Candida albicans, at concentrations ranging from 0.1 to 5.16 mg/ml and showed anticancer activity decrease up to 85% at a concentration of 0.5 mg/ml.…”

Evaluation of paralysis time and animal behavior in the open field. by Sunamita de Carvalho Lima (5598089)

“…The last bar in panel A, indicated by the 24 h in the open box, refers to the <i>ip</i> administration of same dose of crotamine (7.5 μg/animal or 0.3 mg/kg BW) in the same animal 24 h after first crotamine administration, showing a significant decrease in the time for paralysis onset compared to the first administration of crotamine in naïve animal, a day before. …”

Systemic status of WT and miR-150 null mutant (miR-150^-/-) mice with normal chow diet or HFD. by Liheng Shi (144105)

“…There is no statistical interaction between miR-150 null mutation and HFD regimen (2-way ANOVA). n = 5 for each group. (C) Wild type mice fed with HFD have a significant decrease of miR-150 expression compared to mice fed with normal diet (Normal; student’s <i>t</i>-test). …”

Reproduction of the effect of post injections of flupentixol in the core of the nucleus accumbens. by Florian Lesaint (522857)

“…<p>Data are expressed as mean S.E.M. (<b>A,B</b>) Reproduction of Saunders et al. …”

Activation of kinin B₁R in the acute disease phase improved the pathology of EAE. by Rafael C. Dutra (205755)

“…<p>The clinical score (A, C and I) and area under the curve (AUC) (B, D and J) were analyzed in the induction (day 0–5), acute (day 7–17) and chronic (day 15–20) phases of EAE, respectively. …”

Data_Sheet_1_Adherence to COVID-19 preventive measures in Sub-Saharan Africa during the 1st year of the pandemic: Pooled analysis of the International Citizen Project on COVID-19 (... by Leonard Ngarka (6036032)

“…</p>Methods<p>Between March and August 2020, the International Citizen Project on COVID-19 consortium (www.icpcovid.com) conducted online surveys in six SSA countries: Benin, Cameroon, Democratic Republic of Congo, Mozambique, Somalia, and Uganda. A five-point individual adherence score was constituted by scoring respondents' observance of the following measures: mask use, physical distancing, hand hygiene, coughing hygiene, and avoiding to touch one's face. …”