Image_1_SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(−/−) Mice.JPEG by Anne-Kathrin Lutz (11758967)

“…Neuronal proliferation was increased, and apoptosis was decreased in young and mature neurons. Additionally, mature patient hiPSC-derived neurons showed dysregulated excitatory signaling and a decrease of a broad range of signaling molecules of the ERK-MAP kinase pathway. …”

Deletion of <i>Foxm1</i> from macrophages induces activation of p38 MAPK pathway. by Chinmayee Goda (8694597)

“…<p><b>(A-B)</b> Interstitial and alveolar macrophages were isolated from bleomycin-treated my<i>Foxm1</i>^-/- and control lungs using FACS sorting. qRT-PCR shows decreased <i>Foxm1</i>, and <i>Dusp1</i> mRNAs and increased <i>Tnf</i>, <i>Ccl5</i>, <i>Il1β</i>, and <i>Il6</i> mRNAs in flow-sorted interstitial and alveolar macrophages from bleomycin-treated my<i>Foxm1</i>^-/- mice. …”

Electroretinographic evidence suggesting that the type 2 diabetic retinopathy of the sand rat <i>Psammomys obesus</i> is comparable to that of humans by Ahmed Dellaa (4840146)

“…In photopic conditions, diabetic rats showed a significant decrease in a- and b-wave (30.4%, 43.4%), photopic negative response (55.3%), 30 Hz flicker (63.7%), OP1-OP4(51.6%, 61.8%, 68.3% and 47.5% respectively) and S-cone (34.7%). …”

Image_1_CD44 Expression Predicts Prognosis of Ovarian Cancer Patients Through Promoting Epithelial-Mesenchymal Transition (EMT) by Regulating Snail, ZEB1, and Caveolin-1.JPEG by Jiayi Zhou (2228527)

“…Moreover, CD44 knockdown caused a decrease in cell clone formation, migration, and invasion of HOPM and HOPM-Snail cells.…”

Table1_Pulmonary vascular adaptations to hypoxia in elite breath-hold divers.pdf by Thomas Kjeld (5685143)

“…Fractional saturation (F)O₂Hb determined by arterial blood-gas-analyses collected after warm-up and a 5-minute pool-apnea (n = 9) decreased by 43%. …”

Table1_Pulmonary vascular adaptations to hypoxia in elite breath-hold divers.pdf by Thomas Kjeld (5685143)

“…Fractional saturation (F)O₂Hb determined by arterial blood-gas-analyses collected after warm-up and a 5-minute pool-apnea (n = 9) decreased by 43%. …”

Table2_Pulmonary vascular adaptations to hypoxia in elite breath-hold divers.pdf by Thomas Kjeld (5685143)

“…Fractional saturation (F)O₂Hb determined by arterial blood-gas-analyses collected after warm-up and a 5-minute pool-apnea (n = 9) decreased by 43%. …”

Video1_Pulmonary vascular adaptations to hypoxia in elite breath-hold divers.mp4 by Thomas Kjeld (5685143)

“…Fractional saturation (F)O₂Hb determined by arterial blood-gas-analyses collected after warm-up and a 5-minute pool-apnea (n = 9) decreased by 43%. …”

Table1_Pulmonary vascular adaptations to hypoxia in elite breath-hold divers.pdf by Thomas Kjeld (5685143)

“…Fractional saturation (F)O₂Hb determined by arterial blood-gas-analyses collected after warm-up and a 5-minute pool-apnea (n = 9) decreased by 43%. …”

Image_2_CD44 Expression Predicts Prognosis of Ovarian Cancer Patients Through Promoting Epithelial-Mesenchymal Transition (EMT) by Regulating Snail, ZEB1, and Caveolin-1.JPEG by Jiayi Zhou (2228527)

“…Moreover, CD44 knockdown caused a decrease in cell clone formation, migration, and invasion of HOPM and HOPM-Snail cells.…”

Table2_Pulmonary vascular adaptations to hypoxia in elite breath-hold divers.pdf by Thomas Kjeld (5685143)

“…Fractional saturation (F)O₂Hb determined by arterial blood-gas-analyses collected after warm-up and a 5-minute pool-apnea (n = 9) decreased by 43%. …”

Video1_Pulmonary vascular adaptations to hypoxia in elite breath-hold divers.mp4 by Thomas Kjeld (5685143)

“…Fractional saturation (F)O₂Hb determined by arterial blood-gas-analyses collected after warm-up and a 5-minute pool-apnea (n = 9) decreased by 43%. …”

Table_1_CD44 Expression Predicts Prognosis of Ovarian Cancer Patients Through Promoting Epithelial-Mesenchymal Transition (EMT) by Regulating Snail, ZEB1, and Caveolin-1.DOC by Jiayi Zhou (2228527)

“…Moreover, CD44 knockdown caused a decrease in cell clone formation, migration, and invasion of HOPM and HOPM-Snail cells.…”

Table2_Pulmonary vascular adaptations to hypoxia in elite breath-hold divers.pdf by Thomas Kjeld (5685143)

“…Fractional saturation (F)O₂Hb determined by arterial blood-gas-analyses collected after warm-up and a 5-minute pool-apnea (n = 9) decreased by 43%. …”

Data_Sheet_1_Epidemiological characteristics and climatic variability of viral meningitis in Kazakhstan, 2014–2019.pdf by Sauran Yerdessov (14324595)

“…</p>Conclusion<p>This is the first study in Kazakhstan investigating the epidemiology and impact of climate on VM using nationwide healthcare data. There was a tendency to decrease the incidence with outbreaks every 5 years, and mortality rates were higher for Russians and other ethnicities compared to Kazakhs, for males compared to females, for elder patients compared to younger patients, and for patients living in rural areas compared to city residents. …”

Video1_Pulmonary vascular adaptations to hypoxia in elite breath-hold divers.mp4 by Thomas Kjeld (5685143)

“…Fractional saturation (F)O₂Hb determined by arterial blood-gas-analyses collected after warm-up and a 5-minute pool-apnea (n = 9) decreased by 43%. …”

PKM2 is efficiently deleted in mature mSC of mutant mice. by Marie Deck (6829379)

“…<b>B</b>- Immunostaining on mouse sciatic nerve sections at increasing ages (a, b: 4 days postnatal (d); c, d: 15 days postnatal; e, f: 30 days postnatal; g, h: 5 months postnatal (m)) shows decreased PKM1 (left panels) and increased PKM2 (right panels) expressions in mSC over time. m: months. …”

Toward Controlling Water Oxidation Catalysis: Tunable Activity of Ruthenium Complexes with Axial Imidazole/DMSO Ligands by Lei Wang (6656)

“…The measured catalytic activities and kinetics of complex <b>1</b>–<b>6</b> revealed details about an important structure–activity relation: the connection between the nature of axial ligands in the combination and either the increase or decrease of the catalytic activity. In particular, an axial DMSO group substantially increases the turnover frequency of WOCs reported in the article, with the ruthenium-complex having one axial 5-bromo-N-methyl-imidazole and one axial DMSO (<b>4</b>), we have obtained a high initial turnover frequency of ∼180 s^–1. …”

Convergent-extension movements drive MpT elongation. by Aditya Saxena (668441)

“…(E) MpTs increase in length from 82.1±0.8 µm at stage 13 to 330.6±24.2 µm 5 hours later (stage 16) (<i>n</i> = 4 aMpTs from four different embryos; ± standard error of the mean [SEM]). …”

Differential handling of ROS at baseline and following oxidative challenge. by Natasha Chandiramani (233718)

“…<p><b>A</b>. Immunofluorescence staining for lipid peroxidation marker 4-HNE (green) shows that baseline ROS level is higher in RR cells (<b>a</b>) than in RS cells (<b>b</b>). …”