GENomE wide analysis of sotalol-induced IKr inhibition during ventricular REPOLarization, “GENEREPOL study”: Lack of common variants with large effect sizes by Joe-Elie Salem (4351000)

“…QTc and TpTe increased by 5.5±3.5% and 15±19.6%, respectively, and TAmp decreased by 13.2±15.5%. …”

Supplementary Material for: Design and Baseline Characteristics of the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease Trial by Bakris G.L. (4681903)

“…The study has at least 90% power to detect a 20% reduction in the risk of primary outcome (overall two-sided significance level α = 0.05), the composite of time to first occurrence of kidney failure, a sustained decrease of eGFR ≥40% from baseline over at least 4 weeks, or renal death. …”

Chemical inhibition of Erb signalling rescues the <i>pde</i> phenotype. by Karen Camargo-Sosa (3809491)

“…<p>(<b>A-H</b>) Treatment of <i>pde</i> embryos with increasing concentrations of Erb inhibitor PD158780 (iErb; 0.5–2.0 μM) or DMSO carrier control from 12–48 hpf (A-D), 19–30 hpf (E-H) and 24–30 hpf (I-L) hpf. …”

PIK3CA promoter activity in SKOV3 (p53 deficient) tumor xenograft model after cisplatin treatment. by Snehal M. Gaikwad (279479)

“…Mouse from control and treated group exhibited specific [Fig. 4a3 (pre-treatment)] signals which did not decrease even after two treatments of cisplatin [Fig. 4a3 (post-treatment)].…”

Methylation Analysis of CpG Orphans by Nicholas C Wong (14627)

“…CpG dinucleotides that are putative MeCP2-binding sites are indicated by solid diamonds. Upon treatment with 5-aza-dC, a number of CpG orphans (Op-4, Op-9, Op-11, Op-12, Op-17, and Op-18) demonstrated a significant decrease in DNA methylation.…”

PTZ increased exploratory behavior in entrained animals during memory tests. by Norman F. Ruby (263642)

“…<p>Arm entries and exploration times for animals from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0072433#pone-0072433-g005" target="_blank">figure 5</a>. …”

Schematic of the reaction observed in real time with the 8-spot smFRET setup. by Antonino Ingargiola (2993055)

“…Complementary DNA strands are labeled at DNA promoter bases with donor (D, green, position -5) and acceptor (A, red, position -8) dyes. After formation of a transcription initiation bubble, the dyes are separated, resulting in medium FRET. …”

Tumour growth results. by Ahmed El Kaffas (552465)

“…Combined USMB+XRT+Dll4 mAb was observed to induce the greatest response, with a decrease in tumour size at 5 days after treatment, followed by growth inhibition lasting for nearly 15 days. …”

DNA fluorescent <i>in situ</i> hybridization confirms the presence of VZV genomes in nuclei of hESC-derived neurons quiescently infected with VZV. by Amos Markus (749748)

“…(C) FISH for VZV genomes in quiescently infected neurons receiving the PI3K inhibitor LY as a reactivation stimulus. After LY treatment there was a slight decrease in the percentage of FISH+ nuclei in the preparations, but 25% of labeled nuclei contained 2 or more puncta, suggesting additional sites of VZV genomes had appeared. …”

Normalized total loss on the Facebook dataset (DCOR with and without RLC). by Hossein Rafieizadeh (22676722)

“…This normalization emphasizes relative convergence behavior (shape and stability) rather than raw magnitudes: with RLC, the total objective continues to decrease in late epochs, whereas without RLC it plateaus, consistent with the ablation trends in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0335135#pone.0335135.t005" target="_blank">Table 5</a>.…”

Relationship between computational time and structure size for different algorithms used in the GNM analysis by Lee-Wei Yang (64052)

“…The computation of the 101 slowest modes using (red squares) exhibits a power law of = 5.9 × 10 . Using the latter two methods sequentially results in a dramatic decrease in computing time without loss of accuracy. …”

The expression of PGC-1α and mitochondrial alteration in Myc-ON mice. by Hyoung-gon Lee (73934)

“…Morphometric analysis demonstrated about 2.5 fold increase of mitochondria number and about 30% decrease of mitochondrial size in the cardiomyocytes of Myc-ON mice (p<0.05) compared with Myc-OFF mice (F). n: nucleus, m: myofibrils, mito: mitochondria. …”

Effect of atorvastatin on HMGB1 and IL-8 levels in HUVEC supernatants. by Alexandre W. S. de Souza (556095)

“…HMGB1 intensity in supernatants increases 8 hours after stimulation and a peak is observed at 24 hours with a decrease at 48 hours. 2B and C – HMGB1 and IL-8 levels are significantly higher at 24 hours in supernatants from HUVEC treated with LPS in comparison to unstimulated HUVEC while pre-incubation with 5 µM atorvastatin followed by LPS stimulation lowered HMGB1 and IL-8 levels significantly at 24 hours in HUVEC's supernatants. …”

Crude glycerol in diets for Nile tilapia in the fattening stage by Lilian Dena dos Santos (7368332)

“…Two hundred Nile tilapia (190±4.5 g) were distributed in 20 tanks, in a completely randomized design. …”

Summary of results & proposed feedback model. by Rainer Machné (160042)

“…<p>7A: temporal flow of expression and functional relationships of cluster transcripts in the 0.7 h system (left to right) and the 5 h system (top to bottom). 7B: summary of observed properties (significant enrichment or biases) of the main gene clusters. 7C: Potential regulatory interactions of broad cellular functionality <i>via</i> the energetic status of the cell, reflected, <i>e</i>.g., in ATP:ADP ratios. …”

Deletion of <i>Foxm1</i> from macrophages induces activation of p38 MAPK pathway. by Chinmayee Goda (8694597)

“…<p><b>(A-B)</b> Interstitial and alveolar macrophages were isolated from bleomycin-treated my<i>Foxm1</i>^-/- and control lungs using FACS sorting. qRT-PCR shows decreased <i>Foxm1</i>, and <i>Dusp1</i> mRNAs and increased <i>Tnf</i>, <i>Ccl5</i>, <i>Il1β</i>, and <i>Il6</i> mRNAs in flow-sorted interstitial and alveolar macrophages from bleomycin-treated my<i>Foxm1</i>^-/- mice. …”

In vivo induction of hepatocellular carcinoma by diethylnitrosoamine and pharmacological intervention in Balb C mice using Bergenia ciliata extracts by K. K. Dar (6274934)

“…The intraperitoneal administration of B. ciliata as a protective agent, produced significant increase in albumin levels with significant decrease in the levels of tumor markers aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), alpha feto protein (AFP), gamma glutamyl transferase (Y-GT), 5 nucleotidase (5NT), glucose-6-phosphate dehydrogenase (G6PDH) and bilirubin. …”

In vivo induction of hepatocellular carcinoma by diethylnitrosoamine and pharmacological intervention in Balb C mice using Bergenia ciliata extracts by K. K. Dar (6274934)

“…The intraperitoneal administration of B. ciliata as a protective agent, produced significant increase in albumin levels with significant decrease in the levels of tumor markers aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), alpha feto protein (AFP), gamma glutamyl transferase (Y-GT), 5 nucleotidase (5NT), glucose-6-phosphate dehydrogenase (G6PDH) and bilirubin. …”

QUALIS: The journal ranking system undermining the impact of Brazilian science by RODOLFO JAFFÉ (10364631)

Table_1_Estimation of Cerebral Hemodynamics and Oxygenation During Various Intensities of Rowing Exercise: An NIRS Study.docx by Mikio Hiura (12176669)

“…We also aimed to examine the effects of peak pulmonary oxygen consumption (V.O_2peak) on cerebral oxygenation.</p>Methods<p>Eleven rowers, consisting out of six athletes and five recreational rowers [two female; age, 27 ± 9 years; height, 171 ± 7 cm, body mass, 67 ± 9 kg; V.O_2peak, 53.5 ± 6.5 mL min^–1 kg^–1] rowed a 13-min session separated by 10 and 3 min, at 70 (Ex_70%) and 80% of V.O_2peak (Ex_80%), respectively, on a rowing ergometer, followed by three sessions of 1-min supramaximal exercise (ExSp). …”