N-Glycomic Changes in Serum Proteins in Type 2 Diabetes Mellitus Correlate with Complications and with Metabolic Syndrome Parameters by Roberto Testa (218036)

“…</p><p>Methods</p><p>We enrolled in the study 562 patients with Type 2 Diabetes Mellitus (T2DM) (mean age 65.6±8.2 years) and 599 healthy control subjects (CTRs) (mean age, 58.5±12.4 years). …”

Effects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing by Joshua N. Farr (799622)

“…High-throughput RNA sequencing (RNAseq), on the other hand, offers an unbiased approach to examine the entire transcriptome. Here we present an RNAseq analysis of human bone samples, obtained from iliac crest needle biopsies, to yield the first <i>in vivo</i> interrogation of all genes and pathways that may be altered in bone with aging and E therapy in humans. 58 healthy women were studied, including 19 young women (mean age ± SD, 30.3 ± 5.4 years), 19 old women (73.1 ± 6.6 years), and 20 old women treated with 3 weeks of E therapy (70.5 ± 5.2 years). …”

Including cell content predictions in the analysis of microarray data improves model fit and enhances the detection of previously-identified diagnosis-related genes in some dataset... by Megan Hastings Hagenauer (5523191)

“…<b>B:</b> We examined a series of differential expression models of increasing complexity, including a base model (M1), a standard model (M2), and three models that included cell type co-variates (M3-M5). …”

Effect of <i>OPA1</i> or <i>Mfn1</i> silencing on mitochondrial Ca²⁺ uptake in permeabilized HeLa cells. by László Fülöp (203208)

“…<p>For the transfection protocol and measurement of fluorescence see legend of <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0025199#pone-0025199-g005" target="_blank">Figure 5</a>. …”

Focal Ischemic Injury with Complex Middle Cerebral Artery in Stroke-Prone Spontaneously Hypertensive Rats with Loss-Of-Function in NADPH Oxidases by Hiroshi Yao (562206)

“…<div><p>By means of introgressing a loss-of-function mutation in the <i>p22phox</i> gene from the Matsumoto Eosinophilia Shinshu (MES) rat to stroke-prone spontaneously hypertensive rats (SHRSP), we constructed the SHRSP-based congenic strain lacking the P22PHOX expression (i.e., lacking NADPH oxidases [NOX] activities) (SHRSP.MES-<i>Cyba</i>^<i>mes</i>/Izm; hereafter referred to as SP.MES). …”

Lovastatin treatment inhibits VEGFR-2 internalization. by Tong T. Zhao (361937)

“…Lovastatin treatments of 0.5, 1 and 5 µM inhibited VEGFR degradation in a dose dependant manner. …”

Table1_Retrospective Recall of Psychological Distress Experienced During the First COVID-19 Lockdown in Italy: Results From the ALT RISCOVID-19 Survey.doc by Francesca Bracone (12014342)

“…</p><p>Methods: Cross-sectional analysis on 1,880 adults (mean age 48.9 ± 14.5 years) from the web-based ALT RISCOVID-19 survey. …”

Timing of drug response by continuous volume data. by Andrea K. Bryan (188581)

“…For example, not only does a volume decrease occur following STS treatment, but there is a decrease in the population's variation. …”

Expression levels of miR199b in human cerebellum and in tumors, and the correlation with prognosis. by Livia Garzia (266719)

“…D) MiR-199b-5p expression by real-time PCR in a panel of five MB cell lines untreated or treated with 5-Aza-C (DAC−/+); the de-methylation induced miR-199b-5p transcription in two cell lines: Med8a and UW228. …”

Supplementary Material for: Randomized Control Study on Hemoperfusion Combined with Hemodialysis versus Standard Hemodialysis: Effects on Middle-Molecular-Weight Toxins and Uremic... by Zhao D. (3071592)

MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1 by Jianran Hu (427397)

“…<div><p>We have observed low expression levels of MARVELD1, a novel tumor repressor, in multiple tumors; however, its function in normal cells has not been explored. …”

BPTES and 968 attenuated CD4⁺ T cell proliferation and activation under normoxia and hypoxia. by Zeynep Sener (3146064)

“…Under hypoxia, only 968 decreased the PI significantly (Mean ± SD, n = 4). …”

Indirect Effects of COVID-19 on Maternal, Neonatal, Child, Sexual and Reproductive Health Services in Kampala, Uganda by Kirsty Le Doare (10716090)

“…We found a rise in adverse pregnancy outcomes for Caesarean sections (5%), haemorrhages related to pregnancy (51%), stillbirths (31%) and low-birth-weight (162%) and premature infant births (400%). …”

Table_2_Sildenafil Alleviates Murine Experimental Autoimmune Encephalomyelitis by Triggering Autophagy in the Spinal Cord.doc by Eduardo Duarte-Silva (10795263)

“…Furthermore, decreased levels of LC3, beclin-1 and ATG5, suggests impaired autophagy, and decreased levels of AMPK in the spinal cord were also detected in EAE mice. …”

Table_1_Sildenafil Alleviates Murine Experimental Autoimmune Encephalomyelitis by Triggering Autophagy in the Spinal Cord.doc by Eduardo Duarte-Silva (10795263)

“…Furthermore, decreased levels of LC3, beclin-1 and ATG5, suggests impaired autophagy, and decreased levels of AMPK in the spinal cord were also detected in EAE mice. …”

Data_Sheet_1_The Association of CSF sTREM2 With Cognitive Decline and Its Dynamic Change in Parkinson's Disease: Analysis of the PPMI Cohort.docx by Qixiong Qin (12882533)

“…However, higher baseline CSF sTREM2 predicted greater global cognitive decline in patients with PD (β = −0.585, p = 0.039). Moreover, after a mean follow-up of 5.51 ± 1.31 years, baseline CSF sTREM2 that elevated in the middle tertile (HR = 2.426, 95% CI: 1.023–5.754, p = 0.044) and highest tertile (HR = 2.833, 95% CI: 1.226–6.547, p = 0.015) were associated with a future high risk of cognitive decline. …”

Protective Role of Acidic pH-Activated Chloride Channel in Severe Acidosis-Induced Contraction from the Aorta of Spontaneously Hypertensive Rats by Zhiyong Ma (95708)

“…<div><p>Severe acidic pH-activated chloride channel (I_Cl,acid) has been found in various mammalian cells. In the present study, we investigate whether this channel participates in reactions of the thoracic aorta to severe acidosis and whether it plays a role in hypertension. …”

Proposed model. by Salomé S. Pinho (329642)

“…No significant changes were observed in terms of both promoter methylation status and transcription of <i>CDH1</i> and <i>Mgat5</i>. There was a significant decrease of GnT-III-mediated E-cadherin glycosylation. …”

Impact of Climate Change on Sugarcane Yield in Maceió by Lívia Pilar Melo de Oliveira (10393399)

“…<p></p><p>Abstract In this study, a statistical downscaling model (SDSM) based on the analogous methodology was used to project future patterns of precipitation and temperature in the city of Maceió, east coast of northeastern Brazil (9.7° S; 35.7° W; 64.5m), and to evaluate its impacts on sugar cane yield. …”

Footprint characteristics of the forepaw. by Marianne David-Jürgens (376346)

“…<p>Mean values±SD of the gait parameters print area (A), lengths of the print (C), stride-lengths (B) and track-widths (D) for young (black) and aged rats (red), * p<0.01. …”