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74941
PRC2 components are altered in animal models of diabetes and other endothelial cell types exposed to high glucose.
Published 2015“…[HDMECs = human dermal microvascular endothelial cells, Type 1 = HDMECs isolated from a patient with type 1 diabetes, Type 2 = HDMECs isolated from a patient with type 2 diabetes, * p < 0.05 compared to control/NG; n = 6; data expressed as mean ± SEM, normalized to β-actin and expressed as a fold change of control].…”
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74942
Relationship between Su(H) binding and gene responses.
Published 2013“…Solid lines indicate statistically significant effects (p<0.005 after adjusting for multiple testing); the numbers indicate the estimated mean effect on the log odds (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003162#pgen.1003162.s010" target="_blank">Text S1</a>). …”
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74943
Increased lipid concentrations are common in <i>STHdh</i><sup>Q111/Q111</sup> cell pellets.
Published 2015“…<p>A) Strip-plots summarize the logarithm of the concentration ratios of metabolites altered in mutant, compared to wild-type, in cell pellets (left) or growth media (right) at a false-discovery rate of 10% and fold-change cut-off of +/- 30%. …”
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74944
Navigational performance and reward checking during the auditory and visual virtual spatial navigation tasks.
Published 2013“…Two way ANOVA for effect target vs. other quadrants and auditory vs. visual trial types: Effect of quadrant F(1,8) = 95.16, p< 0.001, Effect of task type: F(1,8) = 2.08, p<0.001, Interaction of quadrant and task type: F(1,8) = 2.08, p = 0.002; Effect of quadrant for auditory task: p = 0.097, target quadrant percentage occupancy: 23.9±0.5% vs. mean non-target occupancy: 25.36±0.17%, note that occupancy is slightly decreased in the target quadrant as animals entering the reward zone are teleported out; for visual task: p<0.001, target quadrant percentage occupancy: 59.6±1.15% vs. mean non-target occupancy: 13.5±0.38%, N = 5. …”
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74945
Fis1ΔTM membrane binding requires negatively charged lipids.
Published 2013“…<p>A vesicle sedimentation assay was used to measure fraction of Fis1ΔTM bound to lipid vesicles as a function of decreasing concentration of anionic DOPG at pH 5.0(A) or pH 7.0(B). …”
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74946
Biomarkers for Diabetic Retinopathy – Could Endothelin 2 Be Part of the Answer? - Fig 1
Published 2016“…<p><b>Edn2 (A) and Ednrb (B) fold changes in mRNA expression in young and mature retinae of wt, Akita, Kimba and Akimba mice</b>. …”
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74947
Source-specific carbon dioxide production and acetoclastic methanogenesis upon anaerobic degradation of dissolved organic matter
Published 2025“…Degradation of one milligram algal DOC yielded 47 µmol CO<sub>2</sub> and 0.04 µmol CH<sub>4</sub>, surpassing soil-derived yields by 7- and 4-fold, respectively. Our study delivers biological and mechanistic evidence of DOM processing in aquatic sediments, contributing to a deeper understanding of the origins and fate of their CO<sub>2</sub> and CH<sub>4</sub> concentrations, that may differ substantially among different types of sediments.…”
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74948
Muscle fiber hypertrophy in response to 6 weeks of high-volume resistance training in trained young men is largely attributed to sarcoplasmic hypertrophy
Published 2019“…The 15 fCSA hypertrophic responders experienced a +23% increase in mean fCSA from PRE to W6 (p<0.001) and, while muscle glycogen concentrations remained unaltered, citrate synthase activity levels decreased by 24% (p<0.001) suggesting mitochondrial volume decreased. …”
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74949
Cluster analysis of QFT-positive patients with uveitis of unknown cause, patients with active pulmonary TB without uveitis and healthy controls.
Published 2018“…Red indicates increased gene expression levels when compared to the geometric mean, and blue indicates decreased gene expression levels when compared to the geometric mean. …”
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74950
Connectivity properties of the SOM-VIP motif support the amplification in the interneuron network.
Published 2019“…Smaller mutual inhibition strengths are sufficient to achieve an amplification index above the amplification threshold <i>A</i> = 0 (right). Inset: The dynamics of the mutual inhibition strength (’weight’) after a step increase of the presynaptic firing rate from 0/s to 5/s for three different values of the initial release probabilities. …”
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74951
Homogeneity and size of alignment domains depend on podium length.
Published 2011“…Down-regulation of cell migration, i.e. simultaneous decrease in the number of podia from 3 to 2 (offset value from 3.5 to 2.5) and the independent probabilistic podium inactivation rate from 2 to 0/d, occurs linearly in the range between and nearest neighbors. is set to 1∶3 for all simulations except for the one shown in panel B (short podia) in which it is set to 0∶2, i.e. down-regulation of migration already occurs at lower cell densities and results in better short range alignment (compare <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0021960#pone-0021960-g009" target="_blank">Figure 9</a>). is the maximum length of a podium (Modeling methods section E).…”
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74952
Calvarial healing by histology.
Published 2010“…(C) Average defect width was calculated on the same specimens. As expected a significant decrease in defect width was appreciated with hASC implantation, with many slides showing complete healing. …”
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74953
Correlation of CD8+ T lymphocyte numbers and DENV viral load.
Published 2015“…<p>In A, viral load was determined on different days of symptoms and a significant decrease was observed in days 5 and 6 when compared to days 1 and 2 after the onset of symptoms (p value = 0.0136). …”
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74954
Western blot analysis with affinity-purified rabbit antisera
Published 2011“…<p><b>Copyright information:</b></p><p>Taken from "Mactinin: a modulator of the monocyte response to inflammation"</p><p>Arthritis Research & Therapy 2003;5(6):R310-R316.…”
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74955
Shape of status distributions as functions of <i>α</i>, with <i>δ</i> = 0.14.
Published 2019“…<p>Increasing <i>α</i> leads to an increase in the level of inequality of the society, while decreasing <i>α</i> leads to a decrease in the level of inequality. …”
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74956
The Portuguese version of the RhinoQOL Questionnaire: validation and clinical application,
Published 2022“…The questionnaire was easy and quick to administer (5.5 min). At three months, there was a significant decrease from baseline for all sub-scale scores, indicating clinical improvement, with an effect size considered as large. …”
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74957
Time profiles for complement regulators Factor H, CR1, DAF, vitronectin, clusterin, and CD59.
Published 2016“…<p>(A, B) The concentrations of Factor H and CR1 decrease, with Factor H showing initially a linear like response. …”
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74958
Face validity using model-estimated change in functioning over time since study entry.
Published 2017“…The BECT had the longest period of follow-up and the lowest physical functioning factor across time since study entry, as compared with the other studies. There is a slight increase from study entry to 1.5 years and a slight decrease from 1.5 years to 2.75 years since study entry. …”
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74959
Sensitivity analysis of chosen slice introduced in Fig 4B.
Published 2025“…<p>The stochastic color map from <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003395#pbio.3003395.g004" target="_blank">Fig 4B</a> (center) is shown with a 5% decrease (left) and a 5% increase (right) applied to parameters <i>S, D, v, K, Q,</i> and <i>η</i>. …”
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74960
Oral Health Policy in Brazil: transformations in the period 2015-2017
Published 2018“…Between 2015 and 2017, there was a 5.8% increase in the number of Oral Health Teams and a 6.4% increase in the number of Dental Specialties Centers. …”