Image_1_MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.TIF by Xin Wang (91924)

“…Real-time PCR, dual-luciferase assay, and western blotting were employed to detect the relationship between miR-20a-5p and CD36. The expression level of miR-20a-5p was decreased in NAFLD patients, HFD mice, and free fatty acid (FFA)-treated HepG2 cells or primary mouse hepatocytes, accompanied by increased lipid production in hepatocytes. …”

Image_3_MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.TIF by Xin Wang (91924)

“…Real-time PCR, dual-luciferase assay, and western blotting were employed to detect the relationship between miR-20a-5p and CD36. The expression level of miR-20a-5p was decreased in NAFLD patients, HFD mice, and free fatty acid (FFA)-treated HepG2 cells or primary mouse hepatocytes, accompanied by increased lipid production in hepatocytes. …”

Image1_Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.JPEG by Dan Sun (140898)

“…Furthermore, the treatment of lidocaine repressed tumor growth of ovarian cancer cells in vivo, in which the miR-382-5p expression was increased while SLC7A11 expression was decreased. …”

Microarray analysis of gene expression in primary rhesus microglial cells cultured for 5 days in the presence of <i>B. burgdorferi</i>, versus microglia cultured in medium alone. by Tereance A. Myers (257282)

“…<p>(A) Five of the ten canonical pathways most affected during co-culture of microglia with <i>B. burgdorferi</i> involved inflammatory signaling (in bold) and occurred in cells isolated from each of two rhesus macaques sampled. …”

Critical temperature <em>T_c</em> (in units of <em>t</em>) for different values of the interpolating parameter <em>a</em> at half-filling (from top to bottom, <em>a</em>... by G Mazzucchi (557358)

“…</strong> Critical temperature <em>T_c</em> (in units of <em>t</em>) for different values of the interpolating parameter <em>a</em> at half-filling (from top to bottom, <em>a</em> = 0, 0.25, 0.5, 0.75, 1).…”

S252W mutation affected Wnt signaling in osteogenically differentiating BMSCs. by Li Zhang (8200)

“…<p>(A) Cluster analysis of a microarray data revealed that Wnt pathway antagonists SRRP1, SFRP2, and SFRP4 were up-regulated 3.8 fold, 2.5 fold, and 2.9 fold in mutant BMSCs, respectively (<i>n</i> = 3). …”

AMPK Mediates Glucocorticoids Stress-Induced Downregulation of the Glucocorticoid Receptor in Cultured Rat Prefrontal Cortical Astrocytes by Shi-Ying Yuan (2937669)

“…Glucocorticoid-induced effects were attenuated by glucocorticoid-inducible kinase 1 (SGK1) inhibitor GSK650394, which also inhibited glucocorticoid induced phosphorylation of Forkhead box O3a (FOXO3a). Furthermore, glucocorticoid-induced down-regulation of GR was mimicked by the inhibition of AMPK and abolished by the AMPK activators or the histone deacetylase 5 (HDAC5) inhibitors. …”

Potential biomarkers detected by NMR and MS, metabolic pathways, as well as fold changes between different groups (<i>n</i> = 6). by Ze-Yun Li (704816)

“…The ratio over 1.00 indicated an increase, while ratio less than 1.00 indicated a decrease. Statistical analysis was performed by one-way analysis of variance followed by LSD test.…”

Decrease of variability of latency between times of peak hand acceleration and gaze saccade onset to the target across parabolas. by Olivier White (284746)

“…The horizontal dashed line in the top panel is positioned at mean latency (132.6 ms). Panel B reports a strong decrease in variability within three parabolas.…”

Effects of metformin on depressive behavior and expression of GR in prefrontal cortex of rat after chronic exposure to CORT. by Shi-Ying Yuan (2937669)

Source data for Figs 1E, 2E, 2G, 3B, 3D, 3H, 5D, 6B, 6E, 7B, 7E, S1A, S1B, S1C, S3B, S4, S5B, S5D, S6, S7B, S7D, S10B, S10C, S11B, S11C, S12B, and S12D. by Yongle Zhang (11355546)

Construction of 3‑Fold-Interpenetrated Three-Dimensional Metal–Organic Frameworks of Nickel(II) for Highly Efficient Capture and Conversion of Carbon Dioxide by Bharat Ugale (3127632)

“…Remarkably, in spite of 3-fold interpenetration, the structures possess one-dimensional channels with dimensions of ∼8.05 × 5.25 Ų. …”

Exercise increases body and ARC temperatures. by Jae Hoon Jeong (215351)

Field evaluation of orange rust reaction and genotyping of molecular markers for the <i>G1</i> gene in a nuclear collection of 299 sugarcane accessions. by Gleicy Kelly Oliveira (19259604)

Model predicted OAE prevalence as a function of total mf prevalence compared with the original survey data obtained from Pion et al. [16]. by Samit Bhattacharyya (173222)

The oxygen level (kPa) for 50 and 100% habitat loss for each species and season under a doubling of atmospheric CO₂. by Emily Slesinger (6837740)

1g-SAR distributions in patient 12 (ID12) for the 1.5 T, 3 T, 7 T, and 10.5 T coils over an axial plane passing through the electrode contacts. by Ehsan Kazemivalipour (7148294)

Activation of MBONs causes a reduction in sucrose consumption. by Justine Chia (5459294)

“…<p>Activation of 3 <i>MBON split-Gal4</i> lines (MB311C, MB078C, MB242A) using Chrimson88 caused decreased consumption of 100 mM sucrose. …”

DataSheet5_Yi-Shen-Hua-Shi granules inhibit diabetic nephropathy by ameliorating podocyte injury induced by macrophage-derived exosomes.ZIP by Mingzhu Liang (11011660)

“…Compared with the exosomes secreted by macrophages after an HG treatment, the exosome from macrophages treated with HG and YSHS granule showed lower inhibitory effects on podocyte activity, accompanied by the decreased upregulating effects of macrophage-derived exosomes on the miR-21a-5p in podocytes. miR-21a-5p mimics could reduce podocyte activity and promote caspase-3 shearing. …”

DataSheet1_Characterization of the PM2.5 aerosol fraction monitored at a suburban site in south-eastern Italy by integrating isotopic techniques and ion beam analysis.docx by Salvatore Romano (683443)

“…The concentrations of these elements showed a significant decrease during the weekend, mostly in the case of elements of anthropogenic origin, according to the data on the PM2.5 temporal evolution. …”