Image_1_Effects of Shear Stress on Production of FVIII and vWF in a Cell-Based Therapeutic for Hemophilia A.TIF by Brady Trevisan (10211405)

“…We found that flow conditions led to a significant increase in KLF2, which induces miRNAs that negatively regulate expression of FVIII and vWF, providing a mechanistic explanation for the reduced expression of these proteins in PLC under conditions of flow. …”

Table_1_Effects of Shear Stress on Production of FVIII and vWF in a Cell-Based Therapeutic for Hemophilia A.DOCX by Brady Trevisan (10211405)

“…We found that flow conditions led to a significant increase in KLF2, which induces miRNAs that negatively regulate expression of FVIII and vWF, providing a mechanistic explanation for the reduced expression of these proteins in PLC under conditions of flow. …”

The postprandial changes in glucose (a), proinsulin (b), insulin (c), free fatty acid (FFA) (d) and triglyceride (TG) (e) concentrations are shown for 180 min after the ingestion o... by H-E. Johansson (82635)

The effect of exogenous ROS on DC lymphocytes. by Larisa Pereboeva (322533)

PpL decreases the DNA content and causes mitochondrial depolarization in Daudi cells being caspase-9 involved. by Daniela Lorenzo (358445)

“…<b>B)</b> Percentage of cells with decreased DNA content (mean ± SEM). Experiments were performed three times with similar results, (** p<0.01 PpL (60 μg/ml) vs PBS, *** p<0.001 PpL (90 μg/ml) vs PBS.). …”

(A) Kank inhibits active RhoA through 14-3-3 by Naoto Kakinuma (46267)

“…(C and D) GFP-Kank but not GFP-Kank inhibits insulin-dependent RhoA activation. We generated tetracycline-inducible stable cells expressing GFP-Kank (lanes 1–4) or GFP-Kank (lanes 5–8) using NIH3T3 cells and tested the levels of active RhoA in these cells with (lanes 2, 4, 6, and 8) or without (lanes 1, 3, 5, and 7) insulin stimulation. …”

Decreased BMP activity in MZ<i>nanog</i> is rescued by knocking down of <i>ctnnb2</i>. by Mudan He (7017239)

“…<p>(A) Relative mRNA level of <i>bmp2b</i>, <i>bmp7</i>, and BMP target <i>vent</i> were reduced in MZ<i>nanog</i> examined by RT-qPCR analysis. …”

Plot of normalized root mean square error (NRMSE) against consistency threshold for different number of time intervals in a set. by Walter Karlen (512763)

Mean and variance of <i>r</i>² between rare and common sites as a function of rate of recombination. by Samuel P. Dickson (242256)

“…Although the mean is a nonincreasing function of recombination, the variance increases then decreases, which shows why the maximum <i>r</i>² between rare and common variants can increase with low amounts of recombination in a region.…”

Mean normalized integrated electromyography (iEMG) values during stance (orange color) and swing phase (blue color) on each grade. by Yuji Takahashi (263525)

Intracellular zinc depletion decreased interaction between <i>L</i>. <i>donovani</i> and host macrophages. by Anjali Kumari (4090345)

In vivo DLS infusion of the mGluR5 inhibitor MPEP at late training stages preserves behavioral sensitivity to contingency change in overtrained mice. by Vincent Paget-Blanc (21807763)

Th1 differentiation and IFN-γ secretion are impaired in <i>ccr2</i>^-/- mice during <i>C</i>. <i>muridarum</i> infection. by Shuaini Yang (20670608)

Spacer decreases p53 transactivation, promoter occupancy and binding in yeast and mammalian cells and <i>in vitro</i>. by Jennifer J. Jordan (53318)

Increasing (S curve) and decreasing (Z curve) sigmoidal membership functions, which were used to standardize the environmental data. by Joseph Maina (138555)

Scatter dot plot of the absolute levels of change in LH and FSH between the baseline and week-15 visit. by Sigrid Nilsson (12647302)

A model of R by Ken-ichi Miyazono (29881)

“…Residues in which a mutation decreased cleavage activity of R.PabI are represented as blue sticks.…”

A schematic diagram depicting the proposed pathway wherein hyperglycemia triggers the release of adipokines that influence endothelial inflammation. by Yousif Jameel Jbrael (17797560)

Activity of hepatic injury associated enzymes was decreased in CD44KO(HFD) compared to WT(HFD) mice. by Hong Soon Kang (386679)

mTOR inhibitors combined with glycolysis inhibitor decreased the colony formation and cell viability in lung cancer cells. by Suhua Jiang (416760)