Fluo-PHB but not fluorescein or fluo-DB induces mitochondrial membrane depolarization. by Pia A. Elustondo (461882)

The small molecule Mek1/2 inhibitor U0126 disrupts the chordamesoderm to notochord transition in zebrafish-6 by Thomas A Hawkins (75712)

Data_Sheet_1_The Cytochrome bd Complex Is Essential for Chromate and Sulfide Resistance and Is Regulated by a GbsR-Type Regulator, CydE, in Alishewanella Sp. WH16-1.PDF by Xian Xia (398501)

“…In this study, we investigated the chromate reduction mechanism of strain WH16-1 through Tn5 transposon mutagenesis. A cytochrome bd (cytbd) Tn5 mutant was generated (Δcytbd), and a detail analysis showed that the following: (1) gene cydE (coding for a GbsR-type regulator) was co-transcribed with the two subunits coding genes of the Cytochrome bd complex (Cytbd), namely, cydA and cydB, based on RT-PCR analysis, and similar gene arrangements were also found in other Alteromonadaceae family strains; (2) the chromate resistance level was dramatically decreased and chromate reduction efficiency also decreased in strain Δcytbd compared to the wild-type and a complemented strain (Δcytbd-C); (3) Cytbd could catalyze the decomposition of H₂O₂ according to the analyses of H₂O₂ decomposition ability, cellular H₂O₂ contents, H₂O₂ inhibition zone, and H₂O₂ sensitivity tests; (4) surprisingly, chromate was not an inducer of the expression of Cytbd, but sulfate induced expression of Cytbd, and sulfate/sulfide resistance levels were also decreased in the Δcytbd strain; (5) the addition of sulfate enhanced the chromate resistance level and reduction efficiency; (6) Cytbd expression was repressed by CydE and derepressed by sulfate based on an in vivo bacterial one hybrid system and in vitro EMSA tests; and (7) DNA footprinting and short-fragment EMSA tests revealed two binding sites of CydE in its promoter region. …”

Implicit task switching in Parkinson’s disease is preserved when on medication by Jacob A. Yaffe (8298813)

Supplementary Material for: Overlapping syndrome of myocarditis, myositis, transaminitis, and myasthenia gravis in patient with hepatocellular carcinoma after treatment with immune... by figshare admin karger (2628495)

Table_1_High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL-17 against M. tuberculosis antigen.pdf by Paul Ogongo (5961161)

Supplementary Material for: Expression, Regulation and Function of Human Metallothioneins in Endothelial Cells by Schulkens I.A. (4147624)

Examples of discordant simple non-neoplastic mucocele cases. by Mark A. Valasek (4093864)

Summary of the significant changes in regional cerebral blood flow (rCBF) of WAS vs. control rats during passive bladder filling as related to a simplified model of the micturition... by Zhuo Wang (18668)

Supplementary Material for: Prevalence of cardiovascular drugs and oral anticoagulants use among persons with and without Parkinson’s disease by Babar B.A. (17608206)

“…Prevalence was calculated in six-month time windows from five years before to five years after PD diagnosis (index date) and compared to a matched cohort without PD using generalized estimating equations. …”

Supplementary Material for: Prevalence of cardiovascular drugs and oral anticoagulants use among persons with and without Parkinson’s disease by Babar B.A. (17608206)

“…Prevalence was calculated in six-month time windows from five years before to five years after PD diagnosis (index date) and compared to a matched cohort without PD using generalized estimating equations. …”

One Hydrogen BondTwo Ways To Build a Structure. The Role of N–H···O Hydrogen Bonds in Crystal Structures of <i>N</i>,<i>N</i>‑Dimethylglycine by Eugene A. Kapustin (1826752)

“…It was hypothesized previously [Kolesov, B. A.; Boldyreva, E. V. J. Raman Spectrosc. 2010, 41, 670−677] that additional side N–H···O hydrogen bonds play an important role in forming the head-to-tail chains of amino acid zwitterions linked via N–H···O hydrogen bonds between the charged −NH₃⁺ and −COO^– terminal groups. …”

One Hydrogen BondTwo Ways To Build a Structure. The Role of N–H···O Hydrogen Bonds in Crystal Structures of <i>N</i>,<i>N</i>‑Dimethylglycine by Eugene A. Kapustin (1826752)

“…It was hypothesized previously [Kolesov, B. A.; Boldyreva, E. V. J. Raman Spectrosc. 2010, 41, 670−677] that additional side N–H···O hydrogen bonds play an important role in forming the head-to-tail chains of amino acid zwitterions linked via N–H···O hydrogen bonds between the charged −NH₃⁺ and −COO^– terminal groups. …”

Supplementary Material for: Twenty years of quiescence after non-stop Remicade® (infliximab) infusions in a child with ocular Behçet disease presenting as hypopyon-anterior uveitis... by Evereklioglu C. (14613002)

Supplementary Material for: Usefulness of color laser scanning ophthalmoscopy and optical coherence tomography angiography in the diagnosis of acute zonal occult outer retinopathy... by figshare admin karger (2628495)

Supplementary Material for: Clinical Outcome and Intraoperative Neurophysiology of the Lance-Adams Syndrome Treated with Bilateral Deep Brain Stimulation of the Globus Pallidus Int... by Mure H. (4147672)

Data Sheet 1_Natural active ingredients targeted inflammatory cytokines and major blinding eye diseases: a two-sample Mendelian randomization and molecular docking analysis.docx by Ying Shao (200846)

“…</p>Conclusion<p>The present study identified inflammatory cytokines with causal relationships to five ocular diseases, revealing potential compounds for treating these diseases, providing a theoretical basis for further clinical practice.…”

Bayesian Tragedy and Categorical Medical Error in Prostate Cancer by Pedro A Lamothe (8101699)

Production of forage potential of utilization of digit grass subjected to high defoliation frequencies by C.A. Rizato (6825131)

Embracing GenAI in Engineering Education: Lessons from the Trenches by Lorena A. Barba (97553)