Downregulation of detoxification genes in villi lacking functional pRb and/or E2F1-2-3 proteins. by Maria Teresa Sáenz Robles (201330)

“…Samples were normalized against an endogenous control (Adh and/or Rpl5). c) Cyp3A protein levels decrease in samples lacking pRb. …”

High-resolution SEM analysis of tip links. by Kateri J. Spinelli (293686)

“…(e, f) Bundles treated with 5 mM EGTA for 5 min showed a marked decrease in bundle Fluo-4 fluorescence and a significant reduction in the number of tip links (g, h). …”

Data Sheet 1_Amyloid-induced mitochondrial network disruption in neurons monitored by STED super-resolution imaging.pdf by Iuliia Golovynska (18880049)

“…As a result, the volume and surface area per mitochondrion decrease by 6-fold and 4-fold, respectively. …”

Timed data for onset and survival. by Alexandre Henriques (359791)

“…(A) Onset of weight decrease was defined as a drop of 5% of the mouse maximal weight. …”

Change in LRAGG in response to IFN Treatment in patients with liver fibrosis. by Anne Lamontagne (418004)

“…(B) In contrast, those patients who responded to IFN and cleared their HCV and started had greater than 5-fold increase over normal at the start of treatment show a significant decrease following treatment (P<0.05) (C). …”

Results from RNAi screen against 1920 <i>Drosophila</i> gene products. by Adam Peltan (112024)

“…Green shading indicates hits that caused a significant increase in phagocytosis. Red shading indicates hits that caused a significant decrease in phagocytosis. …”

Loss of Myoferlin Redirects Breast Cancer Cell Motility towards Collective Migration by Leonithas I. Volakis (155515)

“…MDA-231^MYOF-KD cells exhibited a 2-fold decrease in cell stiffness, a 2-fold increase in cell-substrate adhesion and a 1.5-fold decrease in traction force generation. …”

AZ2.0 by Binay Panda (768771)

“…The updated genome assembly (v2.0) yielded 3- and 3.5-fold increase in N50 and N75, <br>respectively; 2.6-fold decrease in the total number of scaffolds; 1.25-fold increase in the number of <br>valid transcriptome alignments; 13.4-fold less mis-assembly and 1.85-fold increase in the <br>percentage repeat, resulted due to removal of mis-assembly and closure of gaps fromover the earlier <br>assembly (v1.0). …”

Intracellular LF82 multiplication requires stress responses. by Gaëlle Demarre (249248)

“…Horizontal lines indicate viability decrease by 2, 5 and 10 fold compared to WT LF82. Data were analyzed using a Student’s <i>t</i> test: * <i>P</i> <0.05, ** <i>P</i> <0.01, *** <i>P</i> <0.001, **** <i>P</i> <0.0001 (black stars correspond to mutant vs WT, blue stars correspond to mutant vs its complementation).…”

NDGA blocks calcium-induced increase of the <i>PADI</i>3 mRNA levels and impairs c-Jun or c-Fos recruitment at PIE. by Stéphane Chavanas (270094)

“…In NHEKs treated with NDGA, calcium stimulation associated with only a 1.5 fold increase in involucrin mRNA levels. …”

UBE2N and SMARCA4 as novel targets of miR-101. by Siddharth Manvati (391250)

“…(c & d) Real-Time PCR showing a change in expression using Sybergreen and UBE2N and SMARCA4 specific primers, (c) under miR-101 and anti-miR-101 transfected conditions, showing decrease & increase, respectively, and (d) after 12 hrs exposure to 1uM, 5 uM and 10 uM etoposide, in MCF7 cells, confirming UBE2N and SMARCA4 as targets of miR-101, which is induced to 10 fold with 1 uM etoposide. …”

Differences in adipogenic potential and functional capabilities in ASC and in their <i>in vitro</i>-derived adipocytes. by Silvana Baglioni (323841)

“…<p>Expression of the adipogenic genes PPARgamma (A), FABP4 (B) and adiponectin (C) evaluated by quantitative real time RT-PCR is higher in S- compared to derived V-ADIPO. …”

Anti-HBV activity of CDM-3008 in primary cultured human hepatocytes. by Yutaka Furutani (5620139)

“…HBV DNA was decreased with 0.1–100 μM CDM-3008 in a dose-dependent manner. …”

Changes in phosphorylation of cell-cell adhesion proteins. by Yashoda Kandel (6392810)

“…Green arrows represent an increase of at least 1.5-fold in phosphorylation at the specified residue between unfed and PBM mosquitoes, and red arrows represent a decrease of at least 1.5-fold in phosphorylation at the specified residue between unfed and PBM mosquitoes.…”

Effect of SENP1 over-expression on JNK activation and cell viability after overnight or 3 h stimulation with H₂O₂. by Marco Feligioni (287395)

“…<p><b>A</b>) Representative Western blot showing decrease in P-JNK protein levels in cells overexpressing SENP1 following overnight stimulation with H₂O₂. …”

PITX2 promotes ovarian cancer cell growth. by Frederic K. C. Fung (164563)

“…(<b>D</b>) Depletion of endogenous PITX2 reduced cell proliferation in ovarian cancer cells. A 3- to 4- fold of reduction on cell viability in both knockdown clones (K1 and K2) of OV2008 cells (** <i>P</i><0.01) and 2- to 3- fold decrease on cell proliferation in knockdown clones (K1 and K2) of OVCA 433 cells (* <i>P</i><0.05) were observed.…”

Ribosomal S6 phosphorylation in whole brain homogenate. by Dominique F. Leitner (12568901)

“…<b>B)</b> Quantification of total S6 relative to actin indicates variability in baseline levels from sampled brain tissue, as well as one patient with increased expression of a smaller detected band (NYU-002). <b>C)</b> Percentage of phospho-S6 (Ser235/236) relative to total S6 indicates an average 1.19-fold decrease when comparing all Active participants to controls (p = 0.67). …”

Global proteomic changes upon perturbation of Hsp90. by Teresa R. O’Meara (720286)

“…Shading indicates per-gene scaled log-fold change compared with the untreated sample, with blue indicating a decrease and red indicating an increase. …”

Promoter analysis of mouse <i>Mogat1</i>. by Shireesha Sankella (3111030)

“…</b> The nucleotide sequence of the ~0.5 kb region located between -4601 and -4185 which showed a -50-fold decrease in luciferase activity as shown in panel A. …”

Silencing of <i>SREB</i> using RNA interference. by Amber J. Marty (761758)

“…<p>(<b>A-C</b>) Quantitative real-time PCR analysis demonstrated a 1.8–2.5-fold decrease in <i>SREB</i> transcript and derepression of <i>SID1</i> (2.9 6.2-fold increase) and <i>HAPX</i> (1.7 3.2-fold increase) in <i>SREB</i> RNAi strains #6 and #7 compared to controls (GFP reporter, empty vector, GFP-RNAi). …”