The STIM2-TM domain activates the cytosolic region of STIMs less efficiently than that of STIM1. by Sisi Zheng (1574473)

“…Left: average time course of whole-cell I_CRAC currents measured at –100 mV. Currents mediated by STIM1121-ΔK developed significantly more slowly than control (time to peak, 72 ± 7 s versus 147 ± 9 s, <i>n</i> = 7, ****<i>P</i> < 0.0001, <i>t</i> test), with the maximal current density also reduced (–5.5 ± 0.8 pA/pF versus –1.5 ± 0.1 pA/pF, <i>n</i> = 7, *****<i>P</i> < 0.0004, <i>t</i> test). …”

Downregulation of p53-induced Mdm2 by overexpressed HIPK2 by Ying Wang (11406)

“…</p><p>Published online 10 Aug 2001</p><p>PMCID:PMC48146.</p><p></p> (A) Saos2 cells were transiently cotransfected with pEGFP-N and expression constructs coding for wildtype 53, wildtype HIPK2 or the kinase defective HIPK2 mutant K221A as indicated. …”

Principle of time-resolved Scintillation Proximity Assay (SPA) to quantify stability of high-affinity radio-ligand binding to GPCRs. by Randi Westh Hansen (2585833)

“…When radioligands bind to immobilized receptors, energy from the radioisotope decay is efficiently transferred to the scintillator contained in the beads, thus generating a detectable light signal. If the buffer, including detergent, causes the loss of receptor affinity to radiolabeled ligand, the signal will start to decrease irreversibly. …”

Photoconversion of mEOS. by Suzie Dufour (383964)

“…<p>A–B) Images at different time points of a mEOS2 expressing cell during UV-induced photoconversion. …”

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Strain has been used as a tool to modulate the reactivity (e.g., mechanochemistry) and thermal isomerization kinetics of photochromic compounds. …”

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Strain has been used as a tool to modulate the reactivity (e.g., mechanochemistry) and thermal isomerization kinetics of photochromic compounds. …”

Probing Interaction between ssDNA and Carbon Nanotubes by Raman Scattering and Electron Microscopy by Masayuki Shoda (2380057)

“…We report experimental results of Raman scattering showing that single-stranded DNA (ssDNA) effectively modifies the electronic structure of metallic carbon nanotubes with the diameter of 1.5−1.6 nm but not for the same diameter class of semiconducting tubes. …”

Endothelial density analysis by age group of corneal donors in an eye bank in Paraná State, Brazil by Karla Mulinari Vicini (10371090)

“…In the evaluation from the second to the sixth decade, there was no pattern, sometimes there was an increase, sometimes a decrease in the average endothelial density.</p><p></p>…”

Rad51 stimulates expression of integrated copies of HIV-1. by Rafal Kaminski (179554)

“…<p><b>(A)</b> TZM-bl cells multiple endogenous integrated copies of LTR-luciferase were transfected with 0, 3, 10 and 30 ng of pCMV (lanes 1–4 or 5–8, respectively). …”

Reduced but functional CD8+ T-cell compartment after fully-mismatched HLA class I thymus transplantation. by Adriana S. Albuquerque (323475)

“…<p>(A) Circulating CD8+ αβ T-cells analysed 58 months post-transplantation (5% of total lymphocytes; 83cells/µl) by flow cytometry in terms of: naïve/memory/effector phenotype assessed by CD45RA and CD27 expression; levels of activation markers (CD38 and HLA-DR); IFN-γ and IL-2 production upon PMA+ionomycin stimulation; <i>ex vivo</i> frequency of cycling cells (Ki-67+); and <i>ex vivo</i> frequency of apoptotic cells assessed by annexin V staining. …”

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Strain has been used as a tool to modulate the reactivity (e.g., mechanochemistry) and thermal isomerization kinetics of photochromic compounds. …”

Schematic representation of dsRNA- and virus-induced beta cell apoptosis. by Maikel L. Colli (179059)

LCN2 reduced the increase of endothelial permeability in response to TNFα. by Yang Du (506908)

“…(C) TNFα treatment significantly decreased the total protein expression of VE-cadherin, claudin-5, occludin, and ZO-1. *, p<0.05 compared to the control (one-way ANOVA). n = 3 independent experiments. …”

Oligomerization of hIKK2 dimers. by Smarajit Polley (420092)

“…(E) In vitro kinase assay reveals that catalytic activity of hIKK2 with mutations that disrupt the V-shaped interface (lanes 3–5) is drastically reduced compared to wild-type protein (WT-lane 2). …”

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Strain has been used as a tool to modulate the reactivity (e.g., mechanochemistry) and thermal isomerization kinetics of photochromic compounds. …”

Supplementary Material for: Sensitivity of Blood Volume Monitoring for Fluid Status Assessment in Hemodialysis Patients by Maduell F. (4137250)

Specificity and sensitivity of C4BP and FH binding by <i>P. intermedia</i> ATCC 25611. by Sven Malm (326396)

“…<p>A) Binding of 250 kcpm ¹²⁵I-C4BP was competed by using 30 µg (final concentration 1.32 µM) unlabeled C4BP, C) ¹²⁵I-FH binding by <i>P. intermedia</i> ATCC 25611 was competed by 7.5 µg (final concentration 1.25 µM) unlabeled FH. …”

Bat Flight Paths by Cynthia F Moss (16356)

“…Each of these examples shows a decrease in PI as the bat approaches the target and clear examples of sonar strobe groups. …”

Densitometric analyses of western immunoblots of samples obtained from conditionally immortalized CHB50 cortical neuroblasts cultured for 24 or 72 hours following p53 induction (-T... by Zulfiqar F Cheema (3325)

“…</p> During this duration, cultures were maintained either under control conditions or were exposed to E2 alone or E2 with tamoxifen. E2 induced a significant decrease in Fas that was not reversed by concurrent exposure to tamoxifen. …”

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Strain has been used as a tool to modulate the reactivity (e.g., mechanochemistry) and thermal isomerization kinetics of photochromic compounds. …”