Geometric manipulation of identical precursor nets to manipulate pathways to enrich an isomer. by Shivendra Pandey (641975)

“…<p>The net 10 shown in (A) and (B) have identical placement of panels but a single panel indicated by the dotted line is excluded to enhance pathways which feature a propensity for 180° folds. …”

E-CAD levels and cellular localization are modified in fra mutants and in embryos without the DL gradient; related to Fig 4. by Yongqiang Xue (5481848)

“…<p>(A) Wild-type levels of E-CAD decrease sharply from dorsal to ventral regions of the embryo (black circles). …”

Structure–Activity Relationship Studies of Pyrimidine-4-Carboxamides as Inhibitors of <i>N</i>‑Acylphosphatidylethanolamine Phospholipase D by Elliot D. Mock (9930184)

“…Conformational restriction of an <i>N</i>-methylphenethylamine group by replacement with an (<i>S</i>)-3-phenylpiperidine increased the inhibitory potency 3-fold. Exchange of a morpholine substituent for an (<i>S</i>)-3-hydroxypyrrolidine reduced the lipophilicity and further increased activity by 10-fold, affording <b>LEI-401</b> as a nanomolar potent inhibitor with drug-like properties. …”

Markers of osteoclast-mediated bone remodeling is reactivated in ColI(2.3)⁺/Rs1⁺ cochlea. by Omar Akil (558393)

“…<p>Markers of bone remodeling were assessed by immunohistochemistry on dissected 12-week-old male WT and ColI(2.3)⁺/Rs1⁺ cochlea with moderate (Mod) and severe (Sev) fibrous lesions using quantitative PCR. (<b>A</b>) Rs1 transgene expression was absent in WT controls and elevated in moderate (**, p = 0.01) and elevated 30-fold in severe ColI(2.3)⁺/Rs1⁺ cochlea (***, p<0.001). …”

Data_Sheet_1_Trichoderma longibrachiatum (TG1) Enhances Wheat Seedlings Tolerance to Salt Stress and Resistance to Fusarium pseudograminearum.xlsx by Solomon Boamah (11710772)

“…The expression of β-1, 6-glucan synthase (PP4), endochitinase precursor (PH-1), and chitinase (chi18-15) increased by 1. 6, 1. 9, and 1.3-fold on day 14 compared with day 3. Wheat seedlings with combined TG1 + Fg treatments under different NaCl stress levels decreased disease index by an average of 51.89%; increased the superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) activity by an average of 38%, 61%, and 24.96%, respectively; and decreased malondialdehyde (MDA) and hydrogen peroxide (H₂O₂) content by an average of 44.07% and 41.75% respectively, compared with Fg treated seedlings. …”

Table_1_Trichoderma longibrachiatum (TG1) Enhances Wheat Seedlings Tolerance to Salt Stress and Resistance to Fusarium pseudograminearum.docx by Solomon Boamah (11710772)

“…The expression of β-1, 6-glucan synthase (PP4), endochitinase precursor (PH-1), and chitinase (chi18-15) increased by 1. 6, 1. 9, and 1.3-fold on day 14 compared with day 3. Wheat seedlings with combined TG1 + Fg treatments under different NaCl stress levels decreased disease index by an average of 51.89%; increased the superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) activity by an average of 38%, 61%, and 24.96%, respectively; and decreased malondialdehyde (MDA) and hydrogen peroxide (H₂O₂) content by an average of 44.07% and 41.75% respectively, compared with Fg treated seedlings. …”

Ex vivo fitness, CTL escape phenotype and sequence evolution of <i>gag</i> p24 CTL escape mutants. by Ryan M. Troyer (265934)

“…The fold escape conferred by each mutation is displayed here as the ratio of effective peptide concentration (EC₅₀) required to elicit 50% of maximal ELISpot signal relative to the pre-escape peptide <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000365#ppat.1000365-Cao2" target="_blank">[54]</a>. …”

Data_Sheet_1_Brain Activity Associated With Regulating Food Cravings Predicts Changes in Self-Reported Food Craving and Consumption Over Time.DOCX by Nicole R. Giuliani (9632423)

“…However, most research on this topic is limited to one follow-up time point, and single outcome measures. The present study seeks to add to that literature by employing a more refined assessment of food craving and consumption outcomes along with a more detailed neurobiological model of behavior change over several time points. …”

Table_1_Transcriptome analysis provides insights into the response of Lotus corniculatus roots to low-phosphorus stress.xlsx by Xin Zhao (71840)

“…Meanwhile, the main pathways, such as carbohydrate metabolism, acid phosphatases, phosphate transporters and biosynthesis of secondary metabolites, as well as related genes were also screened by performing a KEGG enrichment analysis.</p>Discussion<p>The findings provide an essential point of reference for studying the physiological and molecular mechanism of the response to low-P stress in L. corniculatus.…”

Limb survival dependence on Tie2 in the autoamputation model. by Michael Lekas (134183)

“…(f) Quantification of adductor muscle perfusion capacity on day 14 expressed as a vessel score that is a composite of vessel branching point number, length and end points number. …”

Table_1_Low-Loading of Pt Nanoparticles on 3D Carbon Foam Support for Highly Active and Stable Hydrogen Production.DOCX by Abdulsattar H. Ghanim (5932931)

“…The Pt/CF catalyst with loading amounts as low as 0.06 mg_Pt/cm² (10-fold lower than state-of-the-art commercial electrodes) demonstrated a mass activity of 2.6 ampere per milligram Pt at 200 mV overpotential, nearly 6-fold greater than the commercial Pt/C catalyst tested under similar conditions. …”

Validation of unannotated genes differentially expressed in array hybridization during regeneration of zebrafish spinal cord. by Subhra Prakash Hui (510710)

“…Each horizontal line indicates the expression pattern of each gene and the vertical columns indicate the uninjured control and time points after SCI. The color chart indicates mean fold change of gene expression in each time points. …”

Changes in connectivity strength and network metrics during resting state and task periods. by Thomas P. K. Breckel (455915)

“…Attentionally resilient subjects (blue) began to recover during the post-task phase and showed a decrease in functional connectivity in the direction of the pre-task values, whereas attentionally impaired subjects (red) showed further increases in global connectivity strength until the end of the measurement (see also <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0074125#pone-0074125-g005" target="_blank">Figure 5</a> A). …”

Dose-response effects for 30 minutes luminal histamine treatment. by Qianru Zhang (292683)

“…<p>Histamine (40 mM to 100 mM) significantly (p<0.05) decreases TER in native ovine vocal fold epithelium in a dose-dependent manner. …”

Polymerization kinetics of <i>Plasmodium</i> actins. by Andrea J. Lopez (4990781)

“…Raw data related to panels a-d can be found in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1011174#ppat.1011174.s028" target="_blank">S5 Data</a>, panels e and f in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1011174#ppat.1011174.s029" target="_blank">S6 Data</a>, and panels g and h in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1011174#ppat.1011174.s030" target="_blank">S7 Data</a>.…”

Vulnerability to high fat diet-induced obesity. by Alessandro Bartolomucci (165364)

“…At baseline, when mice were fed standard diet, all experimental groups showed a decrease in body weight, while controls (Con) showed a slight increase (F(3,23) = 3.2, p<0.05). …”

Mendelian randomization highlights the causal role of normal thyroid function on blood lipid profiles by Yanjun Wang (9719672)

Table_1_Diel Patterns of Variable Fluorescence and Carbon Fixation of Picocyanobacteria Prochlorococcus-Dominated Phytoplankton in the South China Sea Basin.docx by Yuyuan Xie (2614804)

“…We found that phytoplankton photosynthetic performance at stations SEATS and SS1 were characterized by a nocturnal decrease, dawn maximum, and midday decrease of the maximum quantum yield of PSII (Fv(′)/Fm(′), which has been denoted as both F_v/F_m and Fv′/Fm′) in the nutrient-depleted surface layer. …”

Structure Based Identification and Characterization of Flavonoids That Disrupt Human Papillomavirus-16 E6 Function by Jonathan J. Cherry (501180)

The interplay between tauopathy and aging through interruption of UPR/Nrf2/autophagy crosstalk in the Alzheimer’s disease transgenic experimental models by Javad Amini (15446400)