Novel lung imaging biomarkers and skin gene expression subsetting in dasatinib treatment of systemic sclerosis-associated interstitial lung disease by Viktor Martyanov (396510)

“…Clinical response was defined as decrease of >5 or >20% from baseline in the modified Rodnan Skin Score (MRSS). …”

Community health workers for non-communicable diseases prevention and control in developing countries: Evidence and implications by Gursimer Jeet (535149)

“…The duration of the studies ranged from mean follow up of 4 months for some risk factors to 19 months, and primary responsibilities of health workers included health promotion, treatment adherence and follow ups. Only a single trial reported all-cause mortality. The pooled effect computed indicated an increase in tobacco cessation (RR: 2.0, 95%CI: 1.11, 3.58, moderate-quality evidence) and a decrease in systolic blood pressure ((MD: -4.80, 95% CI: -8.12, -1.49, I² = 93%, very low-quality evidence), diastolic blood pressure ((MD: -2.88, 95% CI: -5.65, -0.10, I² = 96%, very low-quality evidence)) and blood sugar levels (glycated haemoglobin MD: -0.83%, 95%CI: -1.25,-0.41). …”

Table_1_Embryonic Thermal Manipulation Affects Ventilation, Metabolism, Thermal Control and Central Dopamine in Newly Hatched and Juvenile Chicks.DOCX by Aline C. G. Rocha (10984392)

“…Regarding 14d animals, the HT females showed a decrease in V._E and V.O₂ compared to CT and LT groups, while the HT males displayed a lower V.O₂ compared to CT males, but no changes in V.…”

The bioinfomatics analysis of the M1 macrophage-related gene CXCL9 signature in cervical cancer by Wenxin Liao (18974243)

“…</p> <p>There were 77 positive coexpression genes and 5 negative coexpression genes in M1 macrophage. …”

Table_4_Gegen Qinlian Decoction Coordinately Regulates PPARγ and PPARα to Improve Glucose and Lipid Homeostasis in Diabetic Rats and Insulin Resistance 3T3-L1 Adipocytes.docx by Jun Tu (802496)

“…Nuclear location and activity experiments showed that more PPARγ and PPARα shuttled into nuclear to increase its binding activities with target genes. GQD decreased the phosphorylation level of ERK1/2 and/or CDK5 to elevate PPARγ and PPARα activities in IR-3T3-L1 adipocytes through post-translational modification. …”

Table_3_Gegen Qinlian Decoction Coordinately Regulates PPARγ and PPARα to Improve Glucose and Lipid Homeostasis in Diabetic Rats and Insulin Resistance 3T3-L1 Adipocytes.docx by Jun Tu (802496)

“…Nuclear location and activity experiments showed that more PPARγ and PPARα shuttled into nuclear to increase its binding activities with target genes. GQD decreased the phosphorylation level of ERK1/2 and/or CDK5 to elevate PPARγ and PPARα activities in IR-3T3-L1 adipocytes through post-translational modification. …”

Table_2_Gegen Qinlian Decoction Coordinately Regulates PPARγ and PPARα to Improve Glucose and Lipid Homeostasis in Diabetic Rats and Insulin Resistance 3T3-L1 Adipocytes.docx by Jun Tu (802496)

“…Nuclear location and activity experiments showed that more PPARγ and PPARα shuttled into nuclear to increase its binding activities with target genes. GQD decreased the phosphorylation level of ERK1/2 and/or CDK5 to elevate PPARγ and PPARα activities in IR-3T3-L1 adipocytes through post-translational modification. …”

Image_1_Gegen Qinlian Decoction Coordinately Regulates PPARγ and PPARα to Improve Glucose and Lipid Homeostasis in Diabetic Rats and Insulin Resistance 3T3-L1 Adipocytes.pdf by Jun Tu (802496)

“…Nuclear location and activity experiments showed that more PPARγ and PPARα shuttled into nuclear to increase its binding activities with target genes. GQD decreased the phosphorylation level of ERK1/2 and/or CDK5 to elevate PPARγ and PPARα activities in IR-3T3-L1 adipocytes through post-translational modification. …”

Structural homology models of hGPR83 in putative complexes with arrestin and G-protein. by Anne Müller (103420)

“…<p><b>A)</b> The presented structural hGPR83-arrestin complex homology model (backbone cartoon) is mainly based on the crystal structure of rhodopsin with bound arrestin (PDB entry 5DGY, [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0168260#pone.0168260.ref043" target="_blank">43</a>]), which served as a template for modeling procedures. …”

Latency varies across water conditions. by Mallory E. Udell (11302100)

“…As water temperature is decreased, latency is lengthened. Linear regression indicated that temperature explains 63% of the variance in latency when tested between 47–50°C with the water mixing at a constant, low speed. …”

Characterization of hibiscus sabdariffa fiber as potential reinforcement for denture acrylic resins by Kenneth Nkemdilim Okeke (6071561)

“…<div><p>ABSTRACT This study aimed to determine the characteristics of Hibiscus sabdariffa as a fiber-reinforcement material for denture acrylic resins. …”

IRRIGATION DEFICIT STRATEGIES ON PHYSIOLOGICAL AND PRODUCTIVE PARAMETERS OF 'TOMMY ATKINS' MANGO by MARCELO ROCHA DOS SANTOS (6151754)

“…The partial root-zone drying irrigation with 60 and 40% of ETc causes a decrease in the 'Tommy Atkins' mango yield. The regulated deficit irrigation up to 50% of ETc, applied at the fruit maturation stage, maintain the yield and water use efficiency.…”

Water restriction, salinity and depth influence the germination and emergence of sourgrass by Jackson Zambão (10460748)

Table_1_Shark Antibody Variable Domains Rigidify Upon Affinity Maturation—Understanding the Potential of Shark Immunoglobulins as Therapeutics.docx by Monica L. Fernández-Quintero (6178163)

“…We observed a substantial rigidification upon affinity maturation, which is accompanied by a higher number of contacts, thereby contributing to the decrease in flexibility. …”

Simulations of multiple regulators with different weights and heterogeneous <i>K</i>_{<i>n</i>,<i>i</i>} (related to Fig 4). by Xiangrui Ji (16705908)

“…(C) The deletion of inhibitors is equivalent to a decrease in the division threshold. If the threshold change is small, e.g., <i>inh3</i>Δ, <i>V</i>_<i>b</i> is still proportional to the equivalent threshold so that the CV of <i>V</i>_<i>b</i> remains constant. …”

Arsenic induced ROS production in BEAS-2B cells, which was required for angiogenesis. by Ling-Zhi Liu (20849)

“…Cells were treated with different doses of arsenic as indicated in serum-free medium. DCFH-DA at 5 µM was added to the cells for 15 min. Then the cells were washed and fixed, and the fluorescent images were captured using a fluorescent microscope (upper panel). …”

Are Current Atomistic Force Fields Accurate Enough to Study Proteins in Crowded Environments? by Drazen Petrov (434852)

“…Here, we use explicit-solvent MD simulations and a total of 6.4 µs of simulated time to study wild-type (folded) and oxidatively damaged (unfolded) forms of villin headpiece at 6 mM and 9.2 mM protein concentration. …”

SEPs and HFAs_SEP recorded from the peri-rolandic area and 3D-MRI (patient 1, left hemisphere). by Katsuya Kobayashi (523366)

“…Since most of the induced high frequency activities were within 200 ms from the stimulus onset, we displayed the STFT results across the whole time points and frequencies in 3 dimensions (time, frequency, and power value) in a time window of 220 ms (from 20 ms before to 200 ms after the stimulus onset). …”

Table_2_Identification and Functional Analysis of lncRNA by CRISPR/Cas9 During the Cotton Response to Sap-Sucking Insect Infestation.DOCX by Jie Zhang (64655)

“…Furthermore, CRISPR/Cas9 knock-out mutant of lncD09 and lncA07 showed a decrease of jasmonic acid (JA) content, which potentially lead to increased susceptibility toward insect infestation. …”

Transition of LINE-1 DNA Methylation Status and Altered Expression in First and Third Trimester Placentas by Zhi-ming He (562827)

“…Measurement of the DNMT1, DNMT3A, and DNMT3B expression found a significant reduction of DNMT3B between third and first trimesters, pointing to the possible involvement of this enzyme in the regulation of LINE-1 methylation. …”