Transcriptomics of Desiccation Tolerance in the Streptophyte Green Alga <i>Klebsormidium</i> Reveal a Land Plant-Like Defense Reaction by Andreas Holzinger (153856)

“…</p><p>Principal Findings</p><p>For comparison we first established a reference transcriptome. The high-coverage reference transcriptome includes about 24,183 sequences (1.5 million reads, 636 million bases). …”

Image_1_Effects of Antiepileptic Drugs on Spontaneous Recurrent Seizures in a Novel Model of Extended Hippocampal Kindling in Mice.TIF by Hongmei Song (1639081)

“…Phenytoin (25 mg/kg) and levetiracetam (400 mg/kg) abolished the spontaneous recurrent seizures. Lorazepam (1.5 mg/kg) decreased motor seizure severity but did not reduce the incidence and duration of corresponding hippocampal discharges, implicating its inhibitory effects on seizure spread. …”

Table_1_Prescribed psychotropic medication patterns among treated Foster Care enrollees: a single institution study.DOCX by Celica Glenn Cosme (17335960)

“…This study illustrates prescribing patterns in a community mental health clinic focused on judicious prescribing of psychotropic medications in foster care enrolled youth. …”

Table_1_Regional Dichotomy in Enteric Mucosal Immune Responses to a Persistent Mycobacterium avium ssp. paratuberculosis Infection.XLSX by Antonio Facciuolo (3157941)

“…Cytokine gene expression in tissue and MAP-specific recall responses by mucosal immune cells isolated from PP, lamina propria and mesenteric lymph node revealed interleukin (IL)22 and IL27 as unique correlates of protection associated with decreased MAP infection in discrete PP. This study provides the first description of mucosal immune responses occurring in bovine discrete jejunal PPs and reveals that a significant reduction in MAP infection is associated with specific cytokine responses. …”

Identification of miRNAs that affect p16^INK4A expression during oncogene-induced senescence. by Susanne Marije Kooistra (539891)

“…(f) The average of p16^INK4A induction in 5 independent experiments. …”

Table_1_Social inequality in the association between life transitions into adulthood and depressed mood: a 27-year longitudinal study.docx by Magnus Jørgensen (17183916)

“…Our analyses were based on a 27-year longitudinal dataset (n = 1242) of a Norwegian cohort with 10 time points in total. …”

Table_2_Social inequality in the association between life transitions into adulthood and depressed mood: a 27-year longitudinal study.docx by Magnus Jørgensen (17183916)

“…Our analyses were based on a 27-year longitudinal dataset (n = 1242) of a Norwegian cohort with 10 time points in total. …”

<b>Differential FeS cluster photodamage plays a critical role in regulating excess electron flow through photosystem I</b> by Arjun Tiwari (19114912)

“…Depending on environmental and metabolic conditions, the sustenance of CO₂ fixation rates and optimal metabolism requires diverting the photosynthetic electron flow towards alternative electron transport pathways that divert electrons from linear electron transfer (LET) pathway to molecular oxygen (O₂) and quinones or back from PSI to cytochrome <i>b</i>_<em>6</em><i>f </i>(Cyt<i>b</i>_<em>6</em><i>f</i>), instead of reaching NADP⁺.Here, we studied the photoinhibition of photosystem I and II under changing light conditions from constant growth light (120 µmol photons m^-2 s^-1) to high light (850 µmol photons m^-2 s^-1) for different times. We observed a loss of P700 oxidation capacity (decrease of Pm) and the damage of FeS_X and FeS_A_/B clusters from the GL-exposed and moderately HL-treated WT and <i>pgr5</i> mutants of <i>Arabidopsis thaliana</i>. …”

Data Sheet 1_Real-world data of cadonilimab in recurrent or metastatic cervical cancer in China: a multicentric study.docx by Jian Chen (15340)

“…Background<p>Immunotherapy has become a powerful clinical strategy for treating recurrent or metastatic cervical cancer (R/M CC). …”

Table_2_Imaging response to immune checkpoint inhibitors in patients with advanced melanoma: a retrospective observational cohort study.docx by Mehul Gupta (14306495)

“…Elevated LDH level, mucosal primary site, and BRAF V600E mutation status were associated with decreased likelihood of response. …”

Mild oxidative stress reduces transcription from the EBV <i>Bam</i>HI-Cp in a lymphoblastoid cell-line. by Siddhesh Aras (263042)

“…Small increases were also seen for cells positive for only annexin V or only PI. (B) Paraquat treatment decreases expression of EBNA2 and LMP1, as evaluated by immunoblot. 2×10⁵ control or cells treated with 150 µM paraquat (P150) for 72 hours were examined as described in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000469#s4" target="_blank">Methods</a> for expression of EBNA1, EBNA2 and LMP1. …”

Presentation_2_Imaging response to immune checkpoint inhibitors in patients with advanced melanoma: a retrospective observational cohort study.pptx by Mehul Gupta (14306495)

“…Elevated LDH level, mucosal primary site, and BRAF V600E mutation status were associated with decreased likelihood of response. …”

Presentation_1_Imaging response to immune checkpoint inhibitors in patients with advanced melanoma: a retrospective observational cohort study.pptx by Mehul Gupta (14306495)

“…Elevated LDH level, mucosal primary site, and BRAF V600E mutation status were associated with decreased likelihood of response. …”

Table_1_Imaging response to immune checkpoint inhibitors in patients with advanced melanoma: a retrospective observational cohort study.docx by Mehul Gupta (14306495)

“…Elevated LDH level, mucosal primary site, and BRAF V600E mutation status were associated with decreased likelihood of response. …”

An Endurable Triboelectric Nanogenerator for Wind Energy Harvesting Based on Centrifugal Force Induced Automatic Switching between Sliding and Rolling Modes by Guoliang Ma (6267221)

“…The SM-TENG can supply energy to various commercial sensors at a rotational speed of 90 rpm, light up 232 light-emitting diodes (LEDs), and recharge a 47 uF capacitor to 3 V in 15 s. …”

An Endurable Triboelectric Nanogenerator for Wind Energy Harvesting Based on Centrifugal Force Induced Automatic Switching between Sliding and Rolling Modes by Guoliang Ma (6267221)

“…The SM-TENG can supply energy to various commercial sensors at a rotational speed of 90 rpm, light up 232 light-emitting diodes (LEDs), and recharge a 47 uF capacitor to 3 V in 15 s. …”

An Endurable Triboelectric Nanogenerator for Wind Energy Harvesting Based on Centrifugal Force Induced Automatic Switching between Sliding and Rolling Modes by Guoliang Ma (6267221)

“…The SM-TENG can supply energy to various commercial sensors at a rotational speed of 90 rpm, light up 232 light-emitting diodes (LEDs), and recharge a 47 uF capacitor to 3 V in 15 s. …”

Unsuspected osteochondroma-like outgrowths in the cranial base of Hereditary Multiple Exostoses patients and modeling and treatment with a BMP antagonist in mice by Sayantani Sinha (716150)

“…In vitro studies with mouse embryo chondrogenic cells clarified the mechanisms of LDN-193189 action that turned out to include decreases in canonical BMP signaling pSMAD1/5/8 effectors but interestingly, concurrent increases in such anti-chondrogenic mechanisms as pERK1/2 and <i>Chordin</i>, <i>Fgf9</i> and <i>Fgf18</i> expression. …”

Image2_Identification of novel TMEM231 gene splice variants and pathological findings in a fetus with Meckel Syndrome.JPEG by Qian Zhang (49333)

“…The two variants were predicted to be pathogenic by in silico tools and were classified as pathogenic/likely pathogenic variants according to the American College of Medical Genetics and Genomics guideline. cDNA TA cloning analysis showed that both splice site variants caused a deletion of exon 5. RT-PCR revealed that the expression of TMEM231 was significantly decreased and immunofluorescence showed that the primary cilium was almost absent in the proband’s kidney tissue.…”

Table1_Identification of novel TMEM231 gene splice variants and pathological findings in a fetus with Meckel Syndrome.xlsx by Qian Zhang (49333)

“…The two variants were predicted to be pathogenic by in silico tools and were classified as pathogenic/likely pathogenic variants according to the American College of Medical Genetics and Genomics guideline. cDNA TA cloning analysis showed that both splice site variants caused a deletion of exon 5. RT-PCR revealed that the expression of TMEM231 was significantly decreased and immunofluorescence showed that the primary cilium was almost absent in the proband’s kidney tissue.…”