Analysis of cell cycle progression in irradiated hES cells. by Mary L. Lan (293893)

“…<p>Exponentially growing cultures of hES cells exposed to 5 Gy showed an increase in the proportion of cells in G2/M and a decrease in the proportion of cells in G1. …”

Expression of TGFβ signaling related genes. by Olena Preobrazhenska (317896)

“…<p>Gene expression for CTGF, a downstream mediator of TGFβ signaling, and for TGFβ receptors 1 (Alk5), 2, and 3. …”

shPalladin-harboring myoblasts displayed propulsive myogenic differentiation via precocious expression of myogenic differentiation markers. by Ngoc-Uyen-Nhi Nguyen (723223)

“…<p>C2C12 cells were transfected with shRNA targeting palladin or nontargeting shRNA as a control. Stable transfectants were submitted to a differentiation medium and followed for 5 days in culture (D0 to D5). …”

TAL1 associates with the <i>FUBP1</i> promoter via the <i>GATA</i> element to activate <i>FUBP1</i> expression. by Marlene Steiner (6240392)

“…<p><b>(A)</b> Schematic presentation of the reporter constructs used for luciferase assays. 0.5 kb genomic sequence upstream of the <i>FUBP1</i> transcription start were cloned upstream of the luciferase cDNA (left panel). …”

Experimental procedure and results of Experiment S2. by İlayda Nazlı (19332772)

“…<p>(a) The design and procedure of experiment 2 was identical in all respects to experiment 1, apart from the fact that the leading stimulus was an object presented in the left or right side of the fixation point, and it was followed by the trailing object presented in the left or right side of the fixation point. …”

Dataset for Mathematical Model of in vitro Hepatocellular Cholesterol and Lipoprotein Metabolism, fig. 6 by Yuri Efremov (8450409)

“…A simulation showing the effect of anti-PCSK9 antibodies therapy. …”

Mutation of LUSH^D118 does not affect the responses of OR67d neurons to cVA. by Carolina Gomez-Diaz (408669)

“…There is a small but significant decrease in cVA sensitivity in LUSH^D118A compared to LUSH^wt flies only in the 3.5–4-s time bin (<i>p</i><0.05; Sidak's post hoc multiple comparison tests).…”

Characterization of SCDs as Membrane Maintenance Regulators. by Blair C. R. Dancy (821160)

“…The resulting data are summarized here with species with less replenishment than control RNAi colored light blue (>25% decrease) and dark blue (>50% decrease). See <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0141850#pone.0141850.s001" target="_blank">S1 Dataset</a> for complete source data. …”

Lestaurtinib Inhibition of the JAK/STAT Signaling Pathway in Hodgkin Lymphoma Inhibits Proliferation and Induces Apoptosis by Tania Diaz (212468)

“…In addition, we have analyzed the effect of Lestaurtinib treatment in lymph nodes from four classic HL patients. We observed a decrease in cell viability at 24 hours of treatment in three patients (mean decrease of 27% at 300 nM). …”

Effect of stimulus discontinuity in the model. by Vinay Shirhatti (12872281)

“…White lines indicate the sublinear E and superlinear I response regime where increase in <i>iI</i> causes gamma amplitude to increase and frequency to decrease (this regime is absent in case 3). Oscillations weaken drastically in the network from case 1 to 2 and 3, even when the mean E and I responses do not change as much. …”

New Targets for Drug Discovery against Malaria by Guido Santos (171018)

“…The potential targets include: 1) increasing the death rate of the gametocytes, 2) decreasing the invasion rate of the red blood cells by the merozoites, 3) increasing the transformation of merozoites into gametocytes, 4) decreasing the activation of the immune system by the gametocytes, and finally 5) a combination of the previous target with decreasing the recycling rate of the red blood cells. …”

Reduction of trained cFL models. by Melody K. Morris (115320)

“…Thus, a selection threshold of 5×10⁻⁴ to 7.6×10⁻³ results in the models at the “filter points” noted in (a).…”

Effect of antidepressants on tegu sleep. by Paul-Antoine Libourel (561599)

“…S1 was scored automatically based on the decrease of the eye movement density associated with a low muscle tone, and S2 scored based on the 15-Hz oscillations. …”

Death-related down-regulated expression changes in WR99210-treated parasites. by Karthikeyan Ganesan (269200)

“…Twenty one genes showed a drug-dependent decrease in gene expression (see <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000214#ppat.1000214.s009" target="_blank">Table S5</a> for PlasmoDB gene number).…”

Vaccine induced protection against leukopenia. by Simon P. Graham (59745)

“…<p>Leucokyte numbers remained at pre-vaccination levels throughout the experiment in animals vaccinated five days prior to challenge with A) UK2000/7.1 or B) CBR/93 (filled circles), whereas a significant (P<0.05) decrease occurred rapidly after challenge in unvaccinated animals (open circles) and animals vaccinated one day before challenge that developed clinical signs and were euthanized prior to the end of the experiment (open triangles). …”

Longitudinal evaluation of cell viability by <i>in vivo</i> BLI. by Annette Tennstaedt (834294)

“…(B) SBR (signal to background ratio) normalized to the first time point shows a decrease of cell viability within one week. (+) outliers at least 3x interquartile range.…”

The effect of rottlerin on MACC1 expression. by Manisha Juneja (4059493)

“…<p>(A–B) HCT116 cells were treated with increasing concentrations of rottlerin for 24 h (A) or a single dose of 2.5 μM rottlerin (B) for the time points indicated. …”

Mapping of serum neutralizing activity in high titer, protected RM using BG505 Env PV mutants. by Tysheena P. Charles (3385586)

“…The gray infectivity curves represent mutant PVs that did not reach the pre-defined threshold of a 0.5log10 fold increase or decrease in ID₅₀ compared to the parental BG505 Env. …”

Supplementary Material for: Tofacitinib as Induction and Maintenance Therapy in Japanese Patients with Active Ulcerative Colitis by Suzuki Y. (3596711)

“…In OCTAVE Sustain (NCT01458574), 39 patients with clinical response in OCTAVE Induction 1 were re-randomized to placebo, tofacitinib 5 mg, or 10 mg b.i.d. Efficacy endpoints included: remission (primary endpoint; total Mayo score ≤2; no individual subscore >1; rectal bleeding subscore 0); mucosal healing (Mayo endoscopic subscore ≤1); clinical response (≥30% and ≥3-point decrease from induction study baseline total Mayo score; decrease in rectal bleeding subscore ≥1 or absolute subscore ≤1). …”

Image_2_Chromosomal Aberrations in Blood Lymphocytes as Predictors of Respiratory Function After Stereotactic Lung Irradiation.tif by Zsuzsa S. Kocsis (8422800)

“…We also found connections between the in vitro and in vivo CA values (i.e., dicentrics plus rings after 3 Gy irradiation predicts dicentric-plus-ring value directly after the radiotherapy/V_54 Gy (p = 0.001 24.2%)).</p><p>We found that—after further validation—chromosome aberrations resulted from in vitro irradiation before radiotherapy can be a predictive marker of pulmonary function decrease after lung irradiation.…”