Model of the relationship between lifespan and DR protocols that reduce access to food either by intermittent exposure (left panel) or nutrient dilution (right panel). by Richard C. Grandison (375194)

“…In this example, increasing access to the concentrated diet causes lifespan to rise to a peak (DR) beyond which lifespan decreases. At some point (marked here as the ‘point of satiety’) the animal will no longer be able to eat any more food, meaning the nutrition level it experiences is capped and no further increase in availability will further decrease lifespan. …”

ST266 attenuates RGC loss in mice with mild-moderate EAE optic neuritis. by Keirnan Willett (9946075)

“…(a) The average normalized RGC count across the entire retina shows a decrease in RGC numbers in vehicle-treated EAE mouse eyes (n = 22 eyes) compared to eyes from non-EAE control mice (n = 44 eyes) (*p<0.05). …”

Inhibition of NF-κB signaling impedes TNF-α-induced increase in proliferation and angiogenic signaling. by Michael Boyle (433024)

“…(<b>B</b>) MTT assay showing a decrease in TNF-α-induced increase in proliferation, in DPSC challenged with varying concentrations of NBD domain peptide (5 and 10 µM). …”

IT BoNT-B reduces IPLT formalin-evoked C-Fos activation. by Polly P. Huang (352229)

“…Bars represent mean ± SEM; P-value<0.5.</p>…”

Datasheet1_Multimodality 3D image fusion with live fluoroscopy reduces radiation dose during catheterization of congenital heart defects.pdf by Dimitri Buytaert (7109561)

“…The decrease in the median values of the weight-normalized contrast volume (CMC_BW) in all five subgroups was not significant. …”

File S1 - Optogenetic Measurement of Presynaptic Calcium Transients Using Conditional Genetically Encoded Calcium Indicator Expression in Dopaminergic Neurons by Carmelo Sgobio (652457)

“…(E) Comparison of different inter-stimulus interval (ISI) effects on stability of PreCaTs. Stimulation with 5-min and 3-min ISIs revealed a minor (7–15%) decrease in current amplitude that overlapped with that observed during to our standard 30-sec ISI condition (10–20% decrease). …”

DataSheet_1_Patient-Reported Outcomes-Guided Adaptive Radiation Therapy for Head and Neck Cancer.docx by Sarah Weppler (10931013)

“…Based on logistic regression models, during-treatment dose corrections back to planned values may confer ≥5% decrease in the absolute risk of self-reported physical dysphagia symptoms ≥1 year post-treatment in 1.2% of patients, with a ≥5% decrease in relative risk in 23.3% of patients.…”

Sucrose consumption test. by Rafael Delgado y Palacios (498616)

“…<p>The rats were presented with a sucrose solution (1.5%) for one hour after 14 hours of food and water deprivation in order to evaluate their hedonic state during the CMS procedure (8 weeks). …”

Results for IHD. by Eric V. Strobl (16854789)

“…(F) TWRCI estimated the largest mean CRCEs for MRPL1, TRBV6-2 and FAM241B. (G) The annotated variants only explained a small proportion (<1.5%) of the variance for all CRCE estimates. …”

Curcumin inhibits cell proliferation and down-regulates EGFR activation in gefitinib-resistant NSCLC cell lines. by Jen-Yi Lee (346107)

“…(C) Western blotting analysis showed curcumin decrease the EGF (20 ng/ml)-induced EGFR and pEGFR, expression in CL1-5, A549 and H1975 cells in a dose-dependent manner (1–20 µM). β-actin used as the internal control and the numbers below the row of the EGFR and pEGFR indicate the densitometric values normalized with the relative β-actin value.…”

Intrinsic DNA binding affinity differences for ETS1 and ELF1. by Peter C. Hollenhorst (255761)

“…The K_D of ETS1 and ELF1 for the ETS consensus sequence was 1.7×10⁻⁹ and 1.7×10⁻¹⁰ M, respectively. The fold decrease in affinity due to the A to T change, the C to A change, and the combination of both changes were 1.0, 1.5, and 2.4 for ETS1 and 3.6, 1.9, and 18.3 for ELF1, respectively.…”

Reptin depletion impairs H2AX phosphorylation at serine 139 (γH2AX) after DNA damage. by Anne-Aurélie Raymond (724178)

“…(D) Control or Reptin depleted HuH7 cells were treated with etoposide or irradiated, then fixed at different time points and immunostained for phospho-H2AX. The graphs below show for each treatment the evolution of the number of foci per cell (left) or the fractional decrease of the number of foci, setting the initial time point as 100% (right).…”

Effect of ELAP fractions on apoptotic markers in HepG2 cells. by Daleya Abdulaziz Bardi (560119)

“…<p>(A) HepG2 cells were treated with medium alone and 12.5 µg/mL CF, HF, or BF, then stained with Hoechst 33342, cell membrane permeability, MMP, and cytochrome <i>c</i> dyes. …”

Data Sheet 1_The impact of architectural modifications on relative resistance to fluid flow in ventricular catheters.pdf by Rajesh Kumar Madhavan (20634731)

“…Lumen impingement, representing one obstruction-based pinch point in the lumen, showed a considerable increase in relative resistance as obstruction diameter increased and lumen diameter at the pinch point decreased (P = 0.001, n = 5). …”

Expression levels of p115RhoGEF affect cell migration. by Swapnil S. Kher (513448)

“…During image capture, cells were maintained at 37°C and 5% CO2 using a Live Cell™ chamber. Individual cell positions in sequential images were determined using the cell tracking tool in Slidebook software and x-y co-ordinates with starting points adjusted to (0,0) were plotted. …”

Dose planning study of proton versus photon radiotherapy for head and neck squamous cell carcinoma of unknown primary in the primary and recurrent setting by Anne Ivalu Sander Holm (3996290)

“…However, using protons for re-irradiation only leads to a decrease in the tissue volume receiving a specific dose outside the target overlapping region, e.g., V90Gy_mean was 31, 25, and 22 cm³ for photons-photons, photons-protons, and protons-protons, respectively. …”

Population sorting II. by Xavier Manière (230820)

“…<p>(A) We numerically computed the histograms of the distance traveled by a fictitious population of 1000 worms assuming a Gaussian velocity distribution for each worm with an average parallel velocity given by v₀(1+gnoise(µ)) and a standard deviation of 50 µm/s. …”

Blood pressure variability in the elderly. Association between postprandial and sleeping periods by Fernando Abrão Garcia (4657036)

“…One 24 hours ambulatory blood pressure monitoring was used for measurements and the results were showed in the time-rate index. Results: We observed a decrease in the systolic blood pressure values from preprandial to postprandial and to the sleeping periods (124.7 ± 14.6, 113.2 ± 15.3 and 108.5 ± 13.9mmHg, respectively; p = 0.003). …”

Effect of sagopilone (SAG) on cell proliferation, tubulin cytoskeleton, cell cycle and apoptosis of lung cancer cells. by Sebastian Winsel (222664)

“…Proliferation was measured with crystal violet assay. Mean IC50 values as measure of the half-maximal growth inhibition and standard deviations are shown. 1B, Immunofluorescence staining of α-tubulin (green) and DNA (red) in A549 lung cancer cells after incubation with either vehicle (0.1% ethanol), 2.5 nM, or 40 nM SAG. …”

Phenomenological model links variability in sensory responses to response time. by Anders Ledberg (139974)

“…<p>(<b>A</b>) Example showing that an increase in variability leads to a decrease in mutual information. …”