Waterfall plot showing the quantitative changes in ER, PR, and Ki-67 expression. by Yuqin Ding (623253)

“…(A) ER discordance rate: 10.4% (50/482) of patients, including 36 (7.5%) patients with positive-to-negative conversion and 14 (2.9%) patients with negative-to-positive conversion; (B) PR discordance rate: 17.0% (82/482) of patients, including 57 (11.8%) patients with positive-to-negative conversion and 25 (5.2%) patients with negative-to-positive conversion; (C) Ki-67 discordance rates: 50.4% (243/448) of patients had decreased expression and 27.0% (130/448) of patients had increased expression.…”

IL-1β depletion and IL-1 receptor antagonist treatment alleviated the neutrophilic inflammation. by Wen-Cheng Chao (2817868)

“…<p>The characteristic pulmonary histopathological images (A) of <i>M</i>. <i>marinum</i>-infected <i>Ncf1</i>^<i>-/-</i> mice and WT mice on day-5 with and without IL-1β depletion by a monoclonal antibody directed against IL-1β (150μg on day-1). …”

Adaptation period to diets with low or high fiber on digetibility and faecal characteristics in dogs by T. Ramos (7501706)

“…Fecal consistency of the dogs did not differ among diets and periods (P> 0.05). There was a decrease in fecal pH and ammonia in dogs fed the diet with 15% SH (P< 0.05) after 10 days of feeding (P< 0.05). …”

Snail regulates RELN expression in ESCC cells. by Yi Yuan (180239)

“…<p><b>A&B</b>: Snail protein was increased (<b>A</b>) and RELN mRNA was decreased (<b>B</b>) in a time-dependent manner after 5 ng/ml TGF-β1 treatment in KYSE-510 cells. β-actin served as the loading control in Western blot. …”

Artifacts in FRAP arising from the strength of the intentional photobleach. by Tatsuya Morisaki (631489)

“…Artifactual recoveries were observed with the GFP tag (A) but not the TMR-Halo tag (B). Consistent with previous studies <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0107730#pone.0107730-Mueller2" target="_blank">[9]</a>, the relative size of the recovery with the GFP-tag increased with decreasing strength of the photobleach (colored curves in A). …”

Role of flagellin in intraocular inflammation. by Salai Madhumathi Parkunan (588242)

“…<i>B. cereus</i> flagellin was a weak TLR5 agonist, resulting in significantly less NFκB activity at comparable flagellin concentrations (mean ±SD for two repeated experiments, *P≤0.001).…”

Methylation-sensitive expression of <i>ROS1</i> is evolutionarily conserved. by Ben P. Williams (715604)

“…(<b>E</b>) Relative <i>AlROS1a</i> transcripts are significantly decreased when plants are grown on 5-azaC. …”

DataSheet_1_Risk Factors for Adverse Neurodevelopment in Transient or Persistent Congenital Hyperinsulinism.docx by Marcia Roeper (9704393)

“…In univariate analysis, mildly abnormal neurodevelopment was associated with the diagnosis of persistent CHI (odds ratio (OR) 8.3; p=0.004) and higher birth weight (mean difference 1049 g; p<0.001). Severe hypoglycemic brain injury was associated with the diagnosis of persistent CHI (OR 5.1; p=0.013), being born abroad (OR 18.3; p<0.001) or in a lower-level maternity hospital (OR 4.8; p=0.039), and of note history of hypoglycemic seizures (OR 13.0; p=<0.001), and a delay between first symptoms of hypoglycemia and first blood glucose measurement/initiation of treatment (OR 10.7; p<0.001). …”

DataSheet_1_Treatment Interruptions During Stereotactic Body Radiotherapy for Prostate Cancer.docx by Abigail N. Pepin (11966438)

“…Median length of time to complete treatment was 11 days (range 5–155 days). In patients who experienced a delay, nearly half (45.5%) experienced only a one-day delay. …”

The presence of mRNA in each lung sample as determined via real-time PCR. by Masahiro Ishizuka (795418)

“…The expression levels of IL-17F, TGF-β1, CXCL5 and IL-5 mRNA were significantly decreased in the PDE-challenged mice subjected to anti-IL-17A antibody administration compared with the PDE-challenged mice. …”

Image2_Arnica Montana L. Supercritical Extraction Optimization for Antibiotic and Anticancer Activity.JPEG by Taja Žitek (12521470)

“…The content of proanthocyanidins was highest at a pressure between 18 and 24 MPa. The extracts inhibited three different microorganisms successfully; Staphylococcus aureus, Escherichia coli and Candida albicans, at concentrations ranging from 0.1 to 5.16 mg/ml and showed anticancer activity decrease up to 85% at a concentration of 0.5 mg/ml.…”

Image1_Arnica Montana L. Supercritical Extraction Optimization for Antibiotic and Anticancer Activity.JPEG by Taja Žitek (12521470)

“…The content of proanthocyanidins was highest at a pressure between 18 and 24 MPa. The extracts inhibited three different microorganisms successfully; Staphylococcus aureus, Escherichia coli and Candida albicans, at concentrations ranging from 0.1 to 5.16 mg/ml and showed anticancer activity decrease up to 85% at a concentration of 0.5 mg/ml.…”

Evaluation of paralysis time and animal behavior in the open field. by Sunamita de Carvalho Lima (5598089)

“…The last bar in panel A, indicated by the 24 h in the open box, refers to the <i>ip</i> administration of same dose of crotamine (7.5 μg/animal or 0.3 mg/kg BW) in the same animal 24 h after first crotamine administration, showing a significant decrease in the time for paralysis onset compared to the first administration of crotamine in naïve animal, a day before. …”

Systemic status of WT and miR-150 null mutant (miR-150^-/-) mice with normal chow diet or HFD. by Liheng Shi (144105)

“…There is no statistical interaction between miR-150 null mutation and HFD regimen (2-way ANOVA). n = 5 for each group. (C) Wild type mice fed with HFD have a significant decrease of miR-150 expression compared to mice fed with normal diet (Normal; student’s <i>t</i>-test). …”

Human Wharton’s jelly-derived mesenchymal stem cells (hWJ-MSCs) and recombinant growth regulated oncogene-alpha (GRO-α) inhibit necroptosis in an mdx mice model. by Sang Eon Park (11243760)

“…Quantitative measurements were performed using ImageJ (n = 5), and data are expressed as mean ± SEM. Bars with different superscripts indicate significantly different values (*** <i>p</i> < 0.001, ** <i>p</i> < 0.01). …”

Overexpression of estrogen receptor-α inhibited the production of terminally arrested progeny. by Mine Mumcuoglu (246981)

“…<p>(<b>A</b>) ER-overexpressing (ER-5, ER-7, ER-26) and control (C-8, C-10, C-11) clones were established from T47D cells and tested for ER expression by western blotting using decreasing amounts of total proteins. …”

T-helper cell pathway diagram. by Josephine S. D’Alessandro (814578)

“…Gray lines indicate members of a group. APCs, antigen-presenting cells; CXCR1, chemokine (C-X-C motif) receptor 1; CXCR3, chemokine (C-X-C motif) receptor 3; CXCR5, chemokine (C-X-C motif) receptor 5; CXCL10, chemokine (C-X-C motif) ligand 10; GA, glatiramer acetate; HLADMA, major histocompatibility complex class II, DM alpha; HLADMB, major histocompatibility complex class II, DM beta; HLADQB1, major histocompatibility complex class II, DQ beta 1; ICOSLG, inducible T-cell costimulatory ligand; IL-4, interleukin-4; MHC class II, major histocompatibility complex class II; LTB, lymphotoxin beta (tumor necrosis factor superfamily, member 3); MYD, myeloid differentiation primary response protein; S100A10, S100 calcium-binding protein A10; STAT, signal transducer and activator of transcription; TCR, T-cell receptor; Th, T-helper.…”

Citalopram does not increase neural signals for reward or effort outcomes. by Jacqueline Scholl (3752851)

“…On the contrary, a more lenient time point—by—time point <i>t</i> test analysis of the time courses revealed that in striatum and vmPFC, citalopram, in fact, decreased the relative reward magnitude outcome signal late in the outcome phase (*<i>p</i> < 0.05 for time point—by—time point two-sided <i>t</i> tests). …”

SEAwise Report on improved predictive models of recruitment under different habitat scenarios and incorporating experimental results by Paco Melià (162862)

“…Projections show no relevant changes in herring recruitment under RCP4.5 and a decreasing trend under RCP8.5. Plaice recruitment would decline slightly under RCP8.5 and increase under RCP4.5, but from a lower level than RCP8.5. …”

Cardiac Exposure in the Dynamic Conformal Arc Therapy, Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy of Lung Cancer by Xin Ming (832856)

“…</p><p>Results</p><p>The mean dose to the heart among all 140 plans was 4.5 Gy. …”