Modulation of miR-155 levels in CD4+ Th cells influenced the susceptibility to nTreg-mediated suppression. by Heiko F. Stahl (259735)

“…Parallel assay setup revealed a nearly 25% decreased sensibility for suppression of proliferation. …”

Table_1_Diagnostic Value of Sural Nerve Biopsy: Retrospective Analysis of Clinical Cases From 1981 to 2017.DOCX by Valeria Prada (176235)

“…During the years, the number of annually performed biopsies decreased significantly (p = 0.007), with an increase in the mean age of patients (p < 0.0001). …”

Changes in maximal activities of the chloroplastic glutathione reductase and cellular catalase. by José C. Ramalho (493978)

“…For each enzyme, the mean activity values ± SE (n = 4) followed by different letters express significant differences between temperature treatments for the same water availability level (a, b, c, d, e, f), or between water treatments for each temperature treatment (A, B, C), always separately for each genotype.…”

Changes in chloroplastic maximal activities of Cu,Zn-superoxide dismutase and ascorbate peroxidase. by José C. Ramalho (493978)

“…For each enzyme, the mean activity values ± SE (n = 4) followed by different letters express significant differences between temperature treatments for the same water availability level (a, b, c, d, e), or between water treatments for each temperature treatment (A, B, C), always separately for each genotype.…”

<i>Igf-1r</i> hemizygosity has no effect on AKT and S6K activation or autophagosome numbers in HD mice. by Silvia Corrochano (618848)

“…<p><b>A.. </b><i>Igf-1r</i> deficiency leads to a significant decrease in IGF-1R protein levels (p = 0.0057) but does not significantly affect AKT phosphorylation at Ser473 or Thr308, nor the phosphorylation of S6K at Threonine 389 in half-brain homogenates of 12 weeks old female mice of the indicated genotypes. …”

Kidney gene and protein expression. by Eva Gravesen (4740069)

“…<p>Kidney gene expression of factors related to fibrosis and EMT as well as Wnt signalling was examined in Ctrl rats (<b>a)</b> and in CRF rats (<b>c</b>). In Ctrl rats ICG-001 resulted in a decrease in the expression of Snai1 (snail1), Vim (vimentin), Ctnnb1 (β-catenin), Ccnd1 (cyclinD1) and Tgfb1 (TGF-β), while these effects were eliminated in CRF rats. …”

MiR-20b inhibits PTEN protein expression and increases p-Akt level. by Bin Wang (30851)

“…A sharp increase of miR-20b expression was observed in the Eca-109 cells transfected with miR-20b mimics (A), while KYSE-150 cells transfected with miR-20b inhibitor resulted in a significant decrease of miR-20b expression (B). …”

<i>IP3R1</i> gene expression in rat hippocampus 24 h after neonatal anoxia. by Juliane Midori Ikebara (3628970)

“…(C) Quantification of gene expression of <i>IP3R1</i> (n = 8). A significant decrease in <i>IP3R1</i> gene expression (46%, *<i>P</i> < 0.001) was observed. …”

<i>HdhQ111</i>/+ mice exhibit hypoactivity in the open field. by Sabine M. Hölter (160170)

“…N=19 <i>HdhQ111</i>/+ mice (10 males, 9 females) and 20 Hdh+/+ mice (10 males, 10 females). Bars show mean±SEM. All tests showed a significant genotype p value in a 2-way ANOVA (see text for p values). …”

Recovery cycle analysis and regression models demonstrating the refractoriness and relatively refractory period (RRP) against age. by Hsing-Jung Lai (821293)

“…<p><b>A</b>, Compared to NC1 and NC2 (the meaning of symbols are the same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0141935#pone.0141935.g001" target="_blank">Fig 1</a>), the refractoriness (at 2.5 ms, 91.8±28.0% for patient vs. 27.1±4.5% for NC2, <i>p</i> = 0.007) and relatively refractory period (RRP) (3.59±0.18% for patient vs. 3.04±0.07% for NC2, <i>p</i> = 0.0083) are significantly elevated in motor axons of patients, but not in carriers. …”

Strain-degradation analysis of tunnel structures based on twin-shear unified strength criterion by Yongtao Bai (6483680)

HCMV-Induced Changes in Glycolytic Metabolites by Joshua Munger (66985)

“…Average fold change in the metabolite level (relative to the mock 4-h sample) is plotted on a log₂ axis. Error bars show ± 1 SE of the mean. …”

Neuronal loss in the spiral and vestibular ganglia in <i>Slitrk6</i>-deficient mice. by Kei-ichi Katayama (257931)

“…Both the number of neurons and volume of the spiral ganglion of <i>Slitrk6</i>-knockout mice were significantly lower than those of wild-type mice at E16.5, and they decreased to about a half of those of wild-type mice at P0 (A, B). …”

Data Sheet 1_Beta tACS of varying intensities differentially affect resting-state and movement-related M1-M1 connectivity.pdf by Kym Wansbrough (19711762)

“…For resting-state connectivity, we observed intensity-dependent changes in beta ImCoh: sham and 0.5 mA stimulation resulted in an increase in beta ImCoh, while 1.0 mA and 1.5 mA stimulation decreased beta ImCoh. …”

NCA-1 Activity Is Required for Normal Synaptic Transmission at NMJs by Edward Yeh (42793)

“…</p> <p>(A–D) The <i>nca(lf)</i> mutant mPSCs varied between wild-type (WT) values (<i>nca(lf)</i>, upper trace) and decreased frequency and amplitude (<i>nca(lf)</i>, lower trace). …”

Developmentally regulated promoter-switch transcriptionally controls function during embryonic hematopoiesis-2 by Amir Pozner (78042)

“…Following FACS analysis an equal number (1 × 10) of E15.5 WT or P2Annexin V negative thymocytes were incubated with TPA (20 ng/ml) and ConA (5 μg/ml) for 48 h. …”

DataSheet_1_Optimizing linear energy transfer distribution in intensity-modulated proton therapy using the alternating direction method of multipliers.pdf by Qingkun Fan (17379391)

“…</p>Results<p>The results demonstrate the superiority of ADMM-LET over ICR-LET in terms of LET distribution while achieving a comparable dose distribution. More specifically, for the brain case, the maximum LET (unit: keV/µm) at the optic nerve decreased from 5.45 (ICR-LET) to 1.97 (ADMM-LET). …”

BPLF1 promotes the accumulation of SUMOylated TOP2ccs and cell viability following Etoposide treatment. by Jinlin Li (2267896)

“…<p><b>(A)</b> HEK-rtTA-BPLF1 cells were cultured for 24 h in the presence or absence of 1.5 μg/ml Dox and then treated with 80 μM Etoposide for 30 min followed by detection of DNA trapped TOP2 by RADAR assay. …”

Actin and myosin decrements and concomitant increases in sarcoplasmic protein concentrations persist after one week of detraining. by Cody T. Haun (4183900)

“…<p>All line graph data show individual responses with mean ± standard deviation (SD) values below each time point. fCSA significantly increased from PRE to W6, although W7 fCSA was not different from PRE or W6 (panel a). …”

Workers of the hospital maintenance sector: protection, hearing symptoms and noise exposure by Flávia Elisa Antunes Lemes de Oliveira Ramos (5667182)

“…Noise perception in the maintenance service was medium (53%) and high (44%), evidenced noise levels of 62.0 to 101dB (A). Conclusion: the hearing protector was worn by 59.7% of the workers, the plug model was the most used (47.4%) and 75.8% reported that occupational noise decreased with the use of hearing protectors. …”