Is Moderate Intensity Exercise during Pregnancy Safe for the Fetus? An Open Clinical Trial by Adriana Suely Oliveira Melo (7453088)

“…Results The mean FHR decreased during walking (resting: 137 bpm; treadmill: 98 bpm; recovery: 140 bpm; p<0.001), with bradycardia occurring in 56% of the fetuses in the first 10minutes of exercise, and in 47% after 20minutes. …”

Fig 2 - by Hannah J. Thomas (13730162)

“…Dotted lines represent previously reported clinically meaningful changes. A 5% decrease in weight (equating to 3.5 kg for our study participants) has been considered to be clinically meaningful [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0274082#pone.0274082.ref021" target="_blank">21</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0274082#pone.0274082.ref022" target="_blank">22</a>]. …”

Laser Doppler monitoring during reperfusion. by Pierre-Louis Leger (112790)

“…Upon MCA occlusion, the rCBF dropped to 55±8% of baseline, and additional bilateral CCA occlusion further decreased rCBF to 18±5%. After CCA release, a gradual reperfusion was observed from 30±11% at 1 min to 44±9% 20 min after. …”

In Situ Single-Molecule AFM Investigation of Surface-Induced Fibrinogen Unfolding on Graphite by Evgeniy V. Dubrovin (127600)

“…This transformation is accompanied by a decrease in molecular height from 4–5 to 1–2 nm. …”

Phase advance of the LD cycle alters the distribution but not the total amount of sleep. by Dawn H. Loh (362011)

“…<b>B</b>) A 6 h phase delay of the LD cycle resulted in increased sleep during and after the phase shift, and caused an immediate increase in sleep during the extended 6 h of light, as well as a corresponding decrease in sleep during the dark hours of the following day.…”

In Situ Single-Molecule AFM Investigation of Surface-Induced Fibrinogen Unfolding on Graphite by Evgeniy V. Dubrovin (127600)

“…This transformation is accompanied by a decrease in molecular height from 4–5 to 1–2 nm. …”

In Situ Single-Molecule AFM Investigation of Surface-Induced Fibrinogen Unfolding on Graphite by Evgeniy V. Dubrovin (127600)

“…This transformation is accompanied by a decrease in molecular height from 4–5 to 1–2 nm. …”

Effects of Synthetic N-Terminal 17-Residue Peptide on the Δ2–17 MthK Channels by Mario Meng-Chiang Kuo (376172)

“…<div><p>(A) A single-channel trace (top) shows that the channel open probability decreases when 10 μM synthetic peptide (aa1–17) was added to the perfusate (red bar). …”

Measurement of binary and graded signaling responses by flow cytometry. by Ermelinda Porpiglia (34810)

“…Therefore, a plot of total p-Stat5 MFI versus Epo concentration shows a graded response (here, the Hill coefficient is n_H = 1). …”

Monte Carlo Diffusion-Enhanced Photon Inference: Distance Distributions and Conformational Dynamics in Single-Molecule FRET by Antonino Ingargiola (2993055)

“…It is known that rapid D–A distance fluctuations on the order of the D lifetime (or shorter) can increase the measured mean FRET efficiency and thus decrease the estimated D–A distance. …”

Photobiomodulation and physical exercise on strength, balance and functionality of elderly women by Patricia Gabrielli Vassão (5223599)

“…The strength training program associated with PBM active improved a significant increase, relative to baseline, to the right medial/lateral stability index (p = 0.007) and decrease in the Fall Risk Test (p = 0.005). …”

Table_1_Learning from local knowledge on changes in tree-cover and water availability: the case of the contested agroforested landscape of the Mt. Elgon Water Tower, Uganda.docx by George Kimbowa (18319500)

“…Farmers and key experts perceived a decrease in water availability and a decrease in overall tree cover for the period 1990–2020. …”

Cell type-specific rescue of <i>draper</i> mutant phenotypes with alternative Draper receptor isoforms. by Yuly Fuentes-Medel (260602)

“…(C) Expression of Draper-III in glia provides a partial rescue of the decrease in type Ib bouton number observed in <i>draper</i>^Δ<i>5</i> mutants. …”

Effect of BAK treatment on Cx43 and ZO-1 expression. by Zhenhao Zhang (315529)

“…In comparison, there was no significant decrease of Cx43 and ZO-1 mRNA in BAK treated group (A, B). …”

Ibuprofen and diclofenac affect STAT-3 signalling differentially. by Verena Leidgens (815986)

“…The STAT-3 downstream target c-myc was significantly upregulated by ibuprofen (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140613#pone.0140613.s005" target="_blank">S5A Fig</a>), whereas diclofenac blocked pSTAT-3 and c-myc in a concentration-dependent manner (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140613#pone.0140613.s005" target="_blank">S5B Fig</a>). …”

M-SSA Spectra of Internal Variability. by Andrew Westgate (22386403)

“…<p>M-SSA spectra of internal variability — that is, variances of M-SSA modes ranked in the order of decreasing variance — from <b>(a, b)</b> 20CRv3 and <b>(c, d)</b> ERA-20C reanalysis (blue) and <b>(a, c)</b> CMIP5 and <b>(b, d)</b> nonoutlier CMIP6 simulations (red). …”

The combination of three wound healing agents improved urethane-damaged wound healing environment. by Linxin Liu (829738)

“…<p>(A) LPS exposure mainly decreased MPO and TNFα, whereas BLM exposure and macrophage depletion mainly promoted ROS and 8-OHdG. …”

Calcium release caused by 9.2.27PE±ABT-737 in melanoma cells. by Karianne Risberg (207221)

“…<p>(A) FEMX, Melmet-5 and MelRM cells were subjected to 9.2.27PE (100 ng/ml)+ABT-737 (10 µM) for 16 and 24 h before subjected to flow cytometric analysis using Calcium Green™-1. …”

Expression of CD74, CNTF and bFGF after treatment with EPO or EPO-peptide. by Stephanie Busch (417837)

“…<p>Four week old heterozygous or homozygous male PKD rats (each n = 5) were treated with 0.5 ml/kg body weight DynEpo three times or EPO-like peptide five days a week intraperitoneally for four weeks. …”

Disruption of core-AP2M1 binding abolishes recruitment of AP2M1 to LD and alters the sub-cellular localization of core and its colocalization with E2. by Gregory Neveu (142972)

“…TGN46 (green), demonstrating decreased localization of core to TGN in Huh-7.5 cells electroporated with J6/JFH RNA harboring the Y136A core mutation (right panel) compared with WT core (left panel). …”