List of repeatable biomarkers in the lung compartments (for all markers with ICC>0.60). by Stefan Röpcke (129630)

“…To derive the SD value, that together with the median values of a marker (listed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046207#pone-0046207-t004" target="_blank">table 4</a> and in the Online Supplement) can be used for sample size and power calculations, the respective median needs to be multiplied and divided by the value listed above (Example for HSA in BAL fluid of COPD patients: Approximate level of HSA in BAL is 11 µg/mL (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046207#pone-0046207-t004" target="_blank">table 4</a>), the SD is 1.5×11–11/1.5 = 16.5–7.3 = 9.2 µg/mL). …”

Quantitative Analysis of the Extracellular Response Kinase 1 and 2 (ERK1/2), Calcium-Calmodulin Kinase II (CAMKII), Fragile X Protein (FMRP), and the Nicotinic Acetylcholine Recept... by Robert K. Naviaux (256148)

“…<p>(A) ERK1 (MAPK3) and ERK2 (MAPK1) phosphorylation was decreased by over 90% by gestational poly(IC) exposure and normalized by suramin treatment (Sal-Sal = 100+/−5%; Sal-Sur = 6.2+/−0.8%; PIC-Sal = 9.9+/−2.6%; PIC-Sur = 84+/−2.3%; one-way ANOVA F(3,12) = 241; p<0.0001; n = 4–5 males per group; age = 16 weeks). …”

Tn-Seq identifies genes required or detrimental for the growth of <i>S</i>. <i>aureus</i> under low pH. by Catrin M. Beetham (17797675)

“…The list of genes with a 2-fold decrease (essential genes) or a 2-fold increase (detrimental genes) in the number of transposon insertions and a Benjamini–Hochberg value of ≤ 0.1 were compared between libraries A and B and displayed in Venn diagrams for (E) pH 4.5 and (F) pH 5.5 stress conditions. …”

Flavokawain B (FKB) down-regulates mRNA and protein expression of AR and AR target genes. by Xuesen Li (48046)

“…<p>(<b>A</b>).The protein expression of AR and PSA after indicated treatments for 16 hours or 5 µg/ml FKB for indicated period of times was analyzed by Western blot. α-Tubulin was detected as a loading control. …”

Supplementary Material for: Prognostic Accuracy of Mild Cognitive Impairment Subtypes at Different Cut-Off Levels by Göthlin M. (4092352)

“…For aMCI-md, sensitivity increased and specificity decreased when the cut-off was lowered from 2.0 to 1.5 and 1.0 SD. …”

Proposed model of the dual action of dietary flavones in inhibiting DNA methyltransferase and histone methyltransferase. by Rajnee Kanwal (533137)

“…In DNA methylation, methyl groups are added to a cytosine that is immediately 5′ to a guanine. …”

B-AP imaging in the apical dendrite of CA1 pyramidal cells. by Daniel Minge (199631)

“…Corresponding Ca²⁺ transients (ΔF/F in %) recorded from the <i>sham</i> (black) and the SE cell (red) shown in A and C, respectively, at 5, 45, 105 and 155 µm from the soma (see white arrowheads in A and C, right). …”

Temporal sensitivity of PKA and CaMKII activation during L-LTP induction. by MyungSook Kim (65534)

“…(C) Cumulative PKA activity (measured as area under the curve) shows an exponential increase (τ = 8.5 sec) as inter-train interval is increased. The peak phosphoCaMKII decreases exponentially with temporal interval, exhibiting a frequency sensitivity opposite to that of PKA. …”

Effect of AP-2 depletion on the surface distribution of AP-2 and on the uptake of transferrin. by Emmanuel Boucrot (249080)

“…Representative views of the plane closest to the coverslip (σ2-EGFP) and of an equatorial plane (Tf) show a decrease in punctate σ2-EGFP signals at the cell membrane and inhibition of transferrin uptake. …”

Structural and energetic changes of WT⁺4. by Mika Ito (186830)

“…The structure obtained at 4.28 ns when the number of αHBs starts to decrease, that obtained at 4.59 ns with the <i>E</i>_np-np minimum (−73.58 kcal/mol), and that obtained at 5.29 ns with the notably low <i>E</i>_p-p (−116.13 kcal/mol) are displayed in the black, red, and blue boxes, respectively (F). …”

Endothelial-specific ablation of Serum Response Factor causes hemorrhaging, yolk sac vascular failure, and embryonic lethality-10 by Mary L Holtz (81433)

“…Immunofluorescent analysis revealed a decrease in detectable E-cadherin protein in mutant samples. …”

The efficacy assessment of FM/RME treatment for Class III malocclusion versus untreated controls. by Wei Zhang (405)

“…<p>The comparison was performed using five indices. 1: Angle SNA. The FM treatment group presented a greater increase in SNA than the controls (SMD = 1.39, 95% CI = 0.85–1.94, P < 0.00001). 2: Angle SNB. …”

The efficacy assessment of FM treatment for Class III malocclusion versus untreated controls. by Wei Zhang (405)

“…<p>The comparison was performed using five indices. 1: Angle SNA. The FM treatment group presented a greater increase in SNA than the controls (SMD = 1.78, 95% CI = 1.57–1.99, P < 0.00001). 2: Angle SNB. …”

Dynamic impact approach (DIA) and overrepresented approach (ORA) results of DEG during lactation vs. −30d on bovine chromosomes. by Massimo Bionaz (177852)

“…For the DIA the horizontal bars denote the impact and the colored squares on the right denote the direction of the impact (red = increase; green = decrease) (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0032455#pone-0032455-g001" target="_blank">Figure 1</a> for detailed explanation). …”

Figure 6 by Kevin T. Williams (353973)

“…<p>Densitometry Histograms showing changes in NFkB, c-Fos and c-Jun and pSTAT3 levels in response to sCD154 and C4BP stimulation determined using Western blotting (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0000159#pone-0000159-g005" target="_blank">figure 5</a>). …”

The effect of sonication and heat treatment on the physicochemical, nutritional and microbiological properties of different sugarcane variants by Nazariah JASMI (8183856)

“…Both sugarcane variants were subjected to heat and sonication treatments for 5 and 15 minutes as a method for preservation. …”

Inhibition of full-length wild-type capsid polymerization kinetics by two CA binding agents. by Magdeleine Hung (158371)

“…Assembly reactions were induced by 2-fold dilution of capsid protein into buffer containing 50 mM sodium phosphate pH 7.5, 4 M NaCl at 25°C. The increase of turbidity (absorbance at 350 nm) of 40 µM solution of WT CA in the presence of increasing concentrations of inhibitor (depicted on the right side of kinetic traces) was plotted as a function of time. …”

Drought-induced leaf dehydration in soybean transgenic and WT lines. by Humberto H. Carvalho (516219)

“…Leaf water potential was measured by using a Scholander pump. The leaf ψ_w of stressed wild-type plants declined to a maximum stress of −2.0 MPa, whereas the leaf ψ_w of transgenic plants did not decrease below −1.5 MPa. …”

Sensitivity analysis for the most influential inputs (below the bars). by Niels Rutten (171120)

“…<p>For each surveillance system only inputs are shown that cause at least a 5% increase and decrease of total costs. Surveillance system acronyms: The first part is the sampled material either blood (<u>B</u>), eggs (<u>E</u>) or a combination of blood and eggs (<u>BE</u>). …”

Nucleotide substitutions within the fold-back arms of the novel pre-miR159 genes and the corresponding pairing in the secondary structure among 42 <i>Phalaenopsis</i> species. by Chi-Chu Tsai (668824)

“…</p><p>*Represents increasing stability (new base pairing) of the fold-back structure; ** Represents a minor change in fold-back stability (increase or decrease) without destroying the nucleotide pairing (i.e., A-U→G-U, G-C→G-U, G-U→G-C, or G-U→A-U); *** Represents no change in the fold-back stability or substitutions located in the internal loops</p><p>Nucleotide substitutions within the fold-back arms of the novel pre-miR159 genes and the corresponding pairing in the secondary structure among 42 <i>Phalaenopsis</i> species.…”