Data Sheet 1_Treatment with pemafibrate ameliorates fatty liver index and atherogenic lipid profiles in Japanese patients with type 2 diabetes mellitus.pdf by Toru Suzuki (512729)

“…There was no significant change in hemoglobin A1c level over time. FLI (mean ± standard deviation: 68.1 ± 21.9 vs. 39.6 ± 25.0, P < 0.001), but not FIB-4 index as a marker of hepatic fibrosis (median [interquartile range]: 1.04 [0.78-1.39] vs. 1.01 [0.68-1.36], P = 0.909), was significantly decreased by treatment with pemafibrate for 12M, and the proportion of patients with metabolic dysfunction-associated SLD (MASLD) was significantly decreased from 92.3% (baseline) to 61.5% (12M).…”

<b>ATP and Small Amphiphilic Molecules Act as Molecular Matchmakers to Fine-Tune FET Protein Clusters</b> by Mrityunjoy Kar (22445506)

“…At moderate concentrations (5 mM), the size of the clusters decreases but stabilizes. …”

Tadalafil and Sildenafil illicit association: Stability- indicating HPLC method, photodegradation kinetic and toxicological studies by Mayara Aramburú Pinto (12990201)

“…Thus, further studies on this illicit association are needed. A stability-indicating HPLC method was developed for simultaneous determination of tadalafil (TAD) and sildenafil (SIL) using a C18 column (250 x 4.6 mm, 5 µm). …”

The effect of C-terminal truncation, linker lengths, and target site spacing on methyltransferase activity. by Brian Chaikind (136923)

“…The nature of the DNA at site 1 and site 2 (whether a target or non-target site) is depicted at the bottom of the figure and graph. …”

Pedestrian behavior during evacuation from road tunnel in smoke condition—Empirical results by Jakub Porzycki (5698172)

“…In four experiments pedestrians were exposed to artificial, non-toxic smoke. During evacuation of a group of people gathered in low and moderate level of smokiness (when <i>Cs</i> < 0.5<i>m</i>⁻¹) we observed multi-line patterns created by pedestrians. …”

Growth regulation mechanisms and their impact on shape development. by Frédéric Boudon (305760)

“…(<b>G</b>) Transversal cuts of a dome showing tentative generations of a bump with non-cell autonomous stresses: (G-1) Decreasing wall rigidity (10-fold) in a group of inner cells (blue cells with <i>i.e.…”

Homoleptic Cyclometalated Iridium Complexes with Highly Efficient Red Phosphorescence and Application to Organic Light-Emitting Diode by Akira Tsuboyama (1921528)

“…The complexes studied have the general structure Ir(III)(C−N)₃, where (C−N) is a monoanionic cyclometalating ligand:  2-(5-methylthiophen-2-yl)pyridinato, 2-(thiophen-2-yl)-5-trifluoromethylpyridinato, 2,5-di(thiophen-2-yl)pyridinato, 2,5-di(5-methylthiophen-2-yl)pyridinato, 2-(benzo[<i>b</i>]thiophen-2-yl)pyridinato, 2-(9,9-dimethyl-9<i>H</i>-fluoren-2-yl)pyridinato, 1-phenylisoquinolinato, 1-(thiophen-2-yl)isoquinolinato, or 1-(9,9-dimethyl-9<i>H</i>-fluoren-2-yl)isoquinolinato. …”

Identification of Genes Required for Phagocytosis of <i>C. albicans</i> by Shannon L Stroschein-Stevenson (27364)

“…Cells were lightly fixed, and non-phagocytosed <i>C. albicans</i> were secondarily labeled with a rabbit anti–<i>C. albicans</i> antibody and Cy3-labeled anti-rabbit antibody (red). …”

Caddisfly biodiversity in Pernambuco state, Brazil: overcoming the biodiversity knowledge shortfall and insights into the effects of climate change by Rafael Pereira (6635264)

Diversity portraits. by Hans-Rolf Gregorius (711517)

“…Bottom: Four diversity portraits based on the above difference matrix showing Rényi diversity of different orders <i>a</i> as functions of difference level. In all cases, the diversity function shows a stepwise decrease as the difference level increases (see [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0115312#pone.0115312.ref017" target="_blank">17</a>]).…”

Dataset for Mathematical Model of in vitro Hepatocellular Cholesterol and Lipoprotein Metabolism, fig. 6 by Yuri Efremov (8450409)

Supplemental Figure S1 from Oncogene Pathway Activation in Mammary Tumors Dictates FDG-PET Uptake by James V. Alvarez (14876099)

Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vaso-occlusion, inflammation and anemia by John D. Belcher (190588)

“…In NY1DD and Townes-SS sickle mice, HBI-002 decreased microvascular stasis in a duration-dependent manner. …”

Footprints of Pr77^Gag on the WT and LRI-III mutant packaging signal RNAs. by Suresha G. Prabhu (19797666)

“…All nucleotides that show a reactivity decrease >40% upon Gag addition, also show statistically significant difference according to the Mann–Whitney non parametrical U test (<i>p</i> < 0.05). …”

Data_Sheet_1_Ecophysiological responses of seedlings of six dipterocarp species to short-term drought in Borneo.docx by Tomoaki Ichie (2929254)

“…However, there were interspecific differences in physiological responses to such a decrease in soil water content: S. parvifolia and S. beccariana actively controlled their stomata during drought to reduce water consumption via an isohydric response, but showed an increase (S. parvifolia) or no change (S. beccariana) in leaf drought tolerance; Di. pachyphyllus and Dry. aromatica maintained photosynthesis and transpiration close to the wilting point during drought without reducing water consumption via an anisohydric response, and also increased their leaf drought tolerance over the drying period; and S. curtisii and S. smithiana maintained their photosynthetic capacity without stomatal closure, but showed no change or a slight decrease in leaf drought tolerance. …”

Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2. by Thirumal Kumar, D

“…In the case of D2HGDH protein, the mutations I147S and V444A that are positioned in the beta sheet region exhibited higher Root Mean Square Deviation (RMSD), decrease in compactness and number of intramolecular hydrogen bonds compared to the mutations N439D and D375Y that are positioned in the turn and loop region, respectively. …”
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Soil Quality Indexing Strategies for Evaluating Sugarcane Expansion in Brazil by Maurício R. Cherubin (2552743)

“…Two minimum datasets were selected: one using principal component analysis (7 indicators) and the other based on expert opinion (5 indicators). Non-linear scoring curves were used to interpret the indicator values. …”

Transformation of skin fibroblasts into hematopoietic cells that engraft in NOD-Scid mice. by David M. Harris (216744)

“…(<b>B</b>) Left panel: In a different experiment of co-transfection of skin fibroblasts with <i>HOXB2</i>, <i>HOXB 4,</i> and <i>HOXB5</i> genes, flow cytometry analysis of transfected skin fibroblasts showed that a significant percentage of the total population of the cells expressed the hematopoietic CD45 surface antigen, T-, myeloid-, and B-cell surface markers (CD3, CD14, and CD19, respectively), the immature hematopoietic cell marker CD34, the GM-CSF receptor CD116, and the adhesion molecule CD184 antigens. …”

Supplementary Material for: Assessment of micronuclei frequency in the peripheral blood of adult and pediatric patients receiving fractionated total body irradiation by Kanagaraj K. (17091241)

Supplementary Material for: Assessment of micronuclei frequency in the peripheral blood of adult and pediatric patients receiving fractionated total body irradiation by Kanagaraj K. (17091241)