An autophagy-inducing compound ML246 reduces amyloid load in an autophagy-dependent manner in vitro and in vivo. by Altea Rocchi (3278457)

NSAID administration results in a temporary decrease of richness and alpha diversity of the fecal microbiota. by Canaan M. Whitfield-Cargile (787408)

Heparanase activity in murine (A) and human (B) sepsis. by Lukas Martin (747245)

Heparanase level in murine (A) and human (B) sepsis. by Lukas Martin (747245)

Data_Sheet_1_MxB Disrupts Hepatitis C Virus NS5A–CypA Complex: Insights From a Combined Theoretical and Experimental Approach.PDF by Quanjie Li (447626)

“…<p>The human myxovirus resistance B (MxB) protein is an interferon-induced restriction factor that fights a wide range of viruses. We previously demonstrated that MxB binds to hepatitis C virus (HCV)-encoded non-structural protein 5A (NS5A) and inhibits HCV infection by impairing the formation of cyclophilin A (CypA)–NS5A complex. …”

Functional consequences of absence of glycosylation in class II strains. by Joseph Gault (427444)

<i>Becn1</i>^F121A leads to autophagy hyperactivation in vivo. by Altea Rocchi (3278457)

R848 mediated RANTES, but not TNF-α production, is significantly decreased in TRAM^−/− iBMDMs. by Enda Shevlin (628477)

Binding affinity determination of ACE2 variants with SARS-CoV-2 Spike. by Stuart A. MacGowan (11326845)

PNNs decrease after EE. (A–D₁) PNNs, stained by WFA (red), enwrap DCN projection neurons, labeled by SMI32 antibodies (blue). by Simona Foscarin (231429)

Genomic inactivation of the <i>PIWI</i> gene in <i>L. infantum</i> and <i>L. major</i> strains leads to a decrease in amastigote growth and disease pathology. by Prasad K. Padmanabhan (85254)

Intravitreal ALF-186 decreased the IRI-induced capsase-3 and NF-κB mRNA expression and affected the heat-shock response differently. by Julia Stifter (4621033)

“…<p><b>(A)</b> Fold induction of caspase-3 mRNA expression after PBS, ALF-186, or iALF injection after IRI compared to GAPDH in relation to the corresponding non-ischemic contralateral retina analyzed by RT-PCR (n = 6; mean±SD; *** = p<0.001; *** = p<0.001). …”

S5 Fig - by Cynthia Alsayyah (18452506)

“…This indicates that inhibiting the entry of citrate into mitochondria induces the same effects as inhibiting the synthesis of peroxisomal citrate (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002602#pbio.3002602.g005" target="_blank">Fig 5E</a>). …”

Intravital 2-photon microscopy imaging of acute <i>C</i>. <i>albicans</i> infections of the kidney in real time in a living host. by Fitz Gerald S. Silao (9384713)

Viral loads in serum at day 3 post-EBOV infection. by Olivier Reynard (354756)

Effects of cetrorelix treatment on changes in the KCl-evoked contractions of the non-pregnant uterus (U) and the cecum (C). by Kalman F. Szucs (19353218)

Comparative analysis of the antimicrobial activity of hGRNL, bNK2A, and pNKL against O157 strain EDL933 in Müeller-Hinton broth (MHB) or sodium phosphate buffer (NaPB). by Erika N. Biernbaum (12647386)

HPV16 PsV infection decreases following SLPI treatment or anti-annexin A2 antibody inhibition of A2t. by Andrew W. Woodham (140650)

Table_1_Staple line lockstitch reinforcement decreases clinically relevant pancreatic fistula following distal pancreatectomy: Results of a propensity score matched retrospective a... by Feng Tian (121350)

“…</p>Methods<p>This retrospective study enrolled consecutive patients scheduled to undergo distal pancreatectomy at a large tertiary hospital. A comparison was conducted between lockstitch reinforcement and non-reinforcement for remnant closure during distal pancreatectomies from August 2016 to February 2021. …”

Phenotype and molecular identification of <i>GmNN1/FT2a</i> in stable transgenic soybean plants. by Xinxin Li (281237)