Supplementary Data from HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy by Michael F. Emmons (14935638)

“…S1) HDAC expression levels in melanoma cells S2) Cell lines that are resistant to BRAF inhibitors have upregulated c-Jun protein expression S3) Inhibiting HDAC6 does not resensitize BRAF/MEK resistant cells to BRAF inhibitors S4) BRAF/MEK inhibitor withdrawal decreases HDAC8 expression over time S5) Knocking down or elevating HDAC8 levels does not change cell proliferation S6) Expression of HDAC8 increased ERK activity and resistance upon treatment with BRAF-MEK inhibitors S7) Knocking down HDAC8 in BRAFi naïve cells increased apoptosis and BIM expression while decreasing ERK activity after BRAFi activity. …”

A standardized extract of Centella asiatica (ECa 233) prevents temporomandibular joint osteoarthritis by modulating the expression of local inflammatory mediators in mice by Nattapon ROTPENPIAN (10409963)

“…Methodology A mouse model was induced by analyzing the CFA-injected TMJ on days 7, 14, and 21. …”

Simvastatin treatment reduces the cholesterol content of membrane/lipid rafts, implicating the N -methyl-D-aspartate receptor in anxiety: a literature review by Júlia Niehues da Cruz (12847682)

Study on the Multimodal Anticancer Mechanism of Ru(II)/Ir(III) Complexes Bearing a Poly(ADP-ribose) Polymerase 1 Inhibitor by Yuliang Yang (1954498)

“…A series of novel ruthenium­(II) and iridium­(III) complexes (<b>Ru1</b>–<b>Ru3</b> and <b>Ir1</b>–<b>Ir3</b>) with different ancillary ligands and a PARP-1-inhibitory chelating ligand 2-(2,3-dibromo-4,5-dimethoxybenzylidene)­hydrazine-1-carbothioamide (<b>L1</b>) were designed and prepared. …”

Table2_Preclinical Evidence of Paeoniflorin Effectiveness for the Management of Cerebral Ischemia/Reperfusion Injury: A Systematic Review and Meta-Analysis.DOCX by Anzhu Wang (5501090)

“…Paeonia lactiflora Pall. is a commonly used for ischemic stroke management in traditional Chinese medicine; its main active ingredient is paeoniflorin (PF). …”

Study on the Multimodal Anticancer Mechanism of Ru(II)/Ir(III) Complexes Bearing a Poly(ADP-ribose) Polymerase 1 Inhibitor by Yuliang Yang (1954498)

“…A series of novel ruthenium­(II) and iridium­(III) complexes (<b>Ru1</b>–<b>Ru3</b> and <b>Ir1</b>–<b>Ir3</b>) with different ancillary ligands and a PARP-1-inhibitory chelating ligand 2-(2,3-dibromo-4,5-dimethoxybenzylidene)­hydrazine-1-carbothioamide (<b>L1</b>) were designed and prepared. …”

Study on the Multimodal Anticancer Mechanism of Ru(II)/Ir(III) Complexes Bearing a Poly(ADP-ribose) Polymerase 1 Inhibitor by Yuliang Yang (1954498)

“…A series of novel ruthenium­(II) and iridium­(III) complexes (<b>Ru1</b>–<b>Ru3</b> and <b>Ir1</b>–<b>Ir3</b>) with different ancillary ligands and a PARP-1-inhibitory chelating ligand 2-(2,3-dibromo-4,5-dimethoxybenzylidene)­hydrazine-1-carbothioamide (<b>L1</b>) were designed and prepared. …”

Is circumferential urethral mobilization an overdo? A prospective outcome analysis of dorsal onlay and dorso - lateral onlay BMGU for anterior urethral strictures by Gaurav Prakash (5137481)

Study on the Multimodal Anticancer Mechanism of Ru(II)/Ir(III) Complexes Bearing a Poly(ADP-ribose) Polymerase 1 Inhibitor by Yuliang Yang (1954498)

“…A series of novel ruthenium­(II) and iridium­(III) complexes (<b>Ru1</b>–<b>Ru3</b> and <b>Ir1</b>–<b>Ir3</b>) with different ancillary ligands and a PARP-1-inhibitory chelating ligand 2-(2,3-dibromo-4,5-dimethoxybenzylidene)­hydrazine-1-carbothioamide (<b>L1</b>) were designed and prepared. …”

DataSheet1_Global Burden of Inflammatory Bowel Disease Among Children and Adolescents: A Comprehensive Analysis (1990–2019).DOCX by Xuejie Chen (1408159)

“…During the same period, the DALY numbers decreased by 53.5%, from 243,081.06 to 113,119.86, with all SDI regions experiencing a clear drop in DALYs except high SDI regions. …”

A Myb Transcription Factor of <em>Phytophthora sojae</em>, Regulated by MAP Kinase PsSAK1, Is Required for Zoospore Development by Meng Zhang (154027)

“…Compared with the gene expression levels of the recipient <em>P. sojae</em> strain, several candidates of Myb family were differentially expressed (up or down) in response to the loss of PsSAK1, including of a R2R3-type Myb transcription factor, <em>PsMYB1</em>. qRT-PCR indicated that the transcriptional level of <em>PsMYB1</em> decreased due to <em>PsSAK1</em> silencing. …”

Study on the Multimodal Anticancer Mechanism of Ru(II)/Ir(III) Complexes Bearing a Poly(ADP-ribose) Polymerase 1 Inhibitor by Yuliang Yang (1954498)

“…A series of novel ruthenium­(II) and iridium­(III) complexes (<b>Ru1</b>–<b>Ru3</b> and <b>Ir1</b>–<b>Ir3</b>) with different ancillary ligands and a PARP-1-inhibitory chelating ligand 2-(2,3-dibromo-4,5-dimethoxybenzylidene)­hydrazine-1-carbothioamide (<b>L1</b>) were designed and prepared. …”

Table 1_Case Report: Identification of a novel hemizygous missense RPL10 gene variant in two unrelated patients.docx by Lixia Xu (314199)

“…Whole-exome sequencing identified the same hemizygous missense RPL10 gene variant (NM_006013.5:c.347G>A, p.Arg116Gln) in each patient, inherited from their respective mothers. …”

Supplementary Material for: Association between timing of vascular access creation and mortality in patients initiating hemodialysis: A nationwide cohort study in Japan by Murakami M. (3840961)

“…Introduction: The optimal time for vascular access (VA) creation remains controversial. Methods: We conducted a cohort study using data from the Japanese Society for Dialysis Therapy Renal Data Registry. …”

Indocyanine green fluorescence imaging of cutaneous sulfur mustard injuries in a weanling pig model, 48 hours after agent exposure by John S. Graham (63258)

“…The center lesion is a superficial dermal injury that was generated after a 2-min exposure to sulfur mustard, showing a significant amount of fluorescence indicative of patent blood vessels. …”

Study on the Multimodal Anticancer Mechanism of Ru(II)/Ir(III) Complexes Bearing a Poly(ADP-ribose) Polymerase 1 Inhibitor by Yuliang Yang (1954498)

“…A series of novel ruthenium­(II) and iridium­(III) complexes (<b>Ru1</b>–<b>Ru3</b> and <b>Ir1</b>–<b>Ir3</b>) with different ancillary ligands and a PARP-1-inhibitory chelating ligand 2-(2,3-dibromo-4,5-dimethoxybenzylidene)­hydrazine-1-carbothioamide (<b>L1</b>) were designed and prepared. …”

Study on the Multimodal Anticancer Mechanism of Ru(II)/Ir(III) Complexes Bearing a Poly(ADP-ribose) Polymerase 1 Inhibitor by Yuliang Yang (1954498)

“…A series of novel ruthenium­(II) and iridium­(III) complexes (<b>Ru1</b>–<b>Ru3</b> and <b>Ir1</b>–<b>Ir3</b>) with different ancillary ligands and a PARP-1-inhibitory chelating ligand 2-(2,3-dibromo-4,5-dimethoxybenzylidene)­hydrazine-1-carbothioamide (<b>L1</b>) were designed and prepared. …”

Table1_Preclinical Evidence of Paeoniflorin Effectiveness for the Management of Cerebral Ischemia/Reperfusion Injury: A Systematic Review and Meta-Analysis.XLSX by Anzhu Wang (5501090)

“…Paeonia lactiflora Pall. is a commonly used for ischemic stroke management in traditional Chinese medicine; its main active ingredient is paeoniflorin (PF). …”

SiRNA Inhibits Replication of Langat Virus, a Member of the Tick-Borne Encephalitis Virus Complex in Organotypic Rat Brain Slices by Carola Maffioli (135503)

“…When siRNA was administered to HeLa cells before the infection with Langat virus, a 96.5% reduction of viral RNA and more than 98% reduction of infectious virus particles was observed on day 6 post infection, while treatment after infection decreased the viral replication by more than 98%. …”

External-forcing modulation on temporal variations of hydrothermalism-evidence from sediment cores in a submarine venting field off northeastern Taiwan by Jia-Jang Hung (6029237)

“…<div><p>The temporal variation of sulfur and metals in core sediments off Kueishantao Islet, a hydrothermal vent site at northeastern Taiwan, was explored to elucidate the changes in submarine hydrothermal emanation over a centennial time scale. …”