Inhibition of sphingosine kinase synergizes with ABT-263 to kill leukemia cells by causing accumulation of ceramide and sphingosine while decreasing glucosylceramide and S1P. by Lavona Casson (288527)

<i>L. gasseri</i> BNR17 supplementation decreases high-sucrose diet-induced body weight gain and fat mass accumulation. by Ji-Hee Kang (286128)

Transporter activity of cysteine mutant with only intact disulfide bridge (Cys-249 and Cys-321 residues) decreases in the presence of DTT, TCEP and GSH. by Rugmani Padmanabhan Iyer (381482)

“…<p>Wild type and mutant SNAT4 expressing oocytes were incubated with DTT (0–10 mM) (A), TCEP (0–10 mM) (B) and 10 mM GSH (D). [³H]-alanine uptake assay was performed. …”

<i>sirB⁻</i>, Vic1, Vic2 and T6SS-double mutants showed decreased virulence in planta. by Johanna Nykyri (124297)

The residual signaling activity of γ2-MSH and γ3-MSH in plasma is MCR specific and plasma stability decreased compared to CNS stability. by Karin Löw (8805416)

The effects of clonidine on mean arterial blood pressure, fluid flux and luminal alkalinisation. by Olof Nylander (599995)

“…<p>Duodenum was perfused with isotonic saline for 90 min and clonidine was administered from 30 min as a constant i.v. infusion at a dose of 10 or 50 μg kg^-1 h^-1 (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0273208#pone.0273208.g001" target="_blank">Fig 1</a>). …”

BMDCs produce decreased amounts of IL-23 and IL-6 and become poor stimulators for Th17 after exposure to oxATP in culture. by Ronglan Zhao (658986)

Metformin is effective against ERα^- and ERα⁺ breast cancer cells, and decreases ERα levels. by Gerald Davies (4666435)

Image_5_T2DM may exert a protective effect against digestive system tumors in East Asian populations: a Mendelian randomization analysis.tif by Ni An (511459)

“…</p>Conclusion<p>T2DM is associated with a reduced risk of esophageal, gastric and colorectal cancer and hepatocellular carcinoma in East Asian populations. …”

Image_5_Comprehensive Characterization of Cachexia-Inducing Factors in Diffuse Large B-Cell Lymphoma Reveals a Molecular Subtype and a Prognosis-Related Signature.TIF by Zhixing Kuang (10809975)

Data_Sheet_1_Validation of a five-level triage system in pediatric trauma and the effectiveness of triage nurse modification: A multi-center cohort analysis.pdf by Tien-Tien Liu (14039694)

“…Introduction<p>Triage is one of the most important tasks for nurses in a modern emergency department (ED) and it plays a critical role in pediatric trauma. …”

<i>a69</i> mutants have a defect in <i>Rh5</i> and <i>Rh6</i> expression in R8 photoreceptor cells. by Hong Tan (472478)

“…<i>w</i>^<i>1118</i>; <i>P{etau-lacZ}a69</i> mutants show a disruption in <i>Rh5</i> expression, with a substantial decrease in <i>Rh5</i> expression (<i>Rh5</i> 9%) shown in both section (<b>D</b>) and dissociated ommatidia (<b>E</b>) as well as prominent mispairing between <i>Rh3</i> expressing R7 cells and <i>Rh6</i> expressing R8 cells in the same ommatidia (<b>F</b>) (arrowheads, mispaired 25%). …”

Table_5_GLIPR2: a potential biomarker and therapeutic target unveiled – Insights from extensive pan-cancer analyses, with a spotlight on lung adenocarcinoma.xlsx by Wei Lin (6475)

Image_5_GLIPR2: a potential biomarker and therapeutic target unveiled – Insights from extensive pan-cancer analyses, with a spotlight on lung adenocarcinoma.tif by Wei Lin (6475)

LTB-PDM is associated with decreased spontaneously expressed and antigen - induced frequency of CD8⁺ Tc2 and Tc17 cells. by Nathella Pavan Kumar (129299)

Data Sheet 1_Quantum tunneling and barrier hopping in MgTi2O5 nanoparticles: a study of AC/DC conductivity and dielectric response.pdf by A. S. Salwa (22686665)

“…Additionally, dielectric investigation of MgTi₂O₅ NPs within the frequency range from (200 – 5 MHz) and the temperature range from (318K–433K) revealed that both real (ε₁) and imaginary (ε₂) components of a dielectric permittivity decrease as the frequency increased and increased as a temperature increased due to thermal motion of electrons, which is related to the polarization mechanism.…”

Bone marrow exhibits decreased cellularity and increased apoptosis, but no change in global cytosine methylation, following ablation of the <i>Cxxc1</i> gene. by Kristin T. Chun (668653)

PNA decreases protein production and <i>in vitro</i> and <i>in vivo</i> infection by SFG <i>R</i>. <i>montanensis</i>. by Rebecca S. Pelc (703672)

Hypoxia preconditioning upregulated leptin expression of MSCs. by Panpan Chen (307628)

Map of sampled sites created using ArcGIS software. by Joseph Kagabo (20405114)