GCS in hypothalamic neurons regulates neuronal leptin signaling at the plasma membrane. by Viola Nordström (388258)

“…<p>(A) Stat3 phosphorylation was markedly decreased in Arc sections of <i>Ugcg</i>^{f/f//CamKCreERT2} mice in response to peripheral leptin (5 mg/kg; 45 min) 6 wk p.i. …”

Sholl analysis and spine density analysis in mouse hippocampal neurons. by Qiang-qiang Xia (8060987)

“…D) Sholl analysis of WT and <i>Cul3</i> HET knockouts demonstrates decreased dendritic branching in <i>Cul3</i> HET mutant neurons, a main effect of genotype was observed (P = 0.002, WT N = 30/10 cells/mice; HET N = 30/10). …”

Different conformational changes of sRNA Pab21 and Pab91 are associated with the sequential binding of the sRNP proteins. by Jean-Baptiste Fourmann (14570)

“…(<b>E</b>) Quantification of the decrease in the peak amplitude of the specific RNA positive signal at the λ_max wavelength, generated exclusively by addition of L7Ae to different aCBF5–aNOP10–sRNA complexes. …”

50 µM resveratrol is toxic to C₂C₁₂ myotubes. by Kazuhiko Higashida (351645)

“…<p>(A) Exposure to 50 µM resveratrol (RSV) for 24 h is toxic to C₂C₁₂ myotubes resulting in a decrease in viable cells and (B) a decrease in ATP content. …”

Changes in phosphorylation of proteins associated with post-Golgi vesicle traffic. by Yashoda Kandel (6392810)

“…Green arrows represent an increase of at least 1.5-fold in phosphorylation at the specified residue between unfed and PBM mosquitoes, and red arrows represent a decrease of at least 1.5-fold in phosphorylation at the specified residue between unfed and PBM mosquitoes.…”

Flow cytometry data - Computationally Engineered CRISPR-SpyCas9 High-Fidelity Variants with Improved Specificity and Reduced Non-specific DNA Damage by Roy Rabinowitz (16908351)

“…<p>EGFP-PEST stable cells were co-transfected with one of the sgRNA plasmids and one of the Cas plasmids, together with a reporter plasmid. Five days post transfection cells were trypsinized, incubated 5 min at 37 °C, and neutralized by 150ul FBS-enriched FACS buffer (PBS; 5% FBS; 25mM HEPES Biological industries (Israel) 03-025; 5mM EDTA, Biological industries (Israel) 01-862). …”

TGM2 inhibition by siRNA treatment induces cell apoptosis. by Yin-Cheng Huang (633119)

“…Meningioma cells treated with <i>TGM2</i> siRNA exhibited reduced TGM2 expression in a dose-dependent manner (>80% in 5 nM siRNA). (B) Cell viability assessed using the MTT assay showed 30% decrease of cell survival following 5 nM siRNA exposure. …”

Lpp supplies lipids to peripheral organs. by Wilhelm Palm (148641)

“…<p>(A–D) Changes in wing disc neutral lipids upon LTP or Lpp RNAi, quantified by mass spectrometry (n = 5). …”

MMP-2, MMP-9, TIMP-3 expression and collagenolytic activity in the failing heart. by Federica Limana (216501)

“…(E) TIMP-3 protein levels were lower in failing hearts, both in the border zone and in the infarcted area, than in SO hearts. HMGB1 caused a further decrease in TIMP-3 protein. Both for MMPs (C) and TIMP-3, the same filter was probed with α-tubulin to normalize protein loading (n = 5 for the average results of densitometric analyses of western blots).…”

Transmission kernels. by Elisa Benincà (120328)

“…Parameter values are based on estimates by Boender et al. [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008009#pcbi.1008009.ref005" target="_blank">5</a>] for the Dutch epidemic of avian influenza in 2003, but with rescaling to account for the decrease in number of farms (from 5,360 to 2,157) and concomitant increase in size of farms since 2003.…”

The absence of Pfd1 causes alterations in the intragenic distribution of RNA polymerase II. by Gonzalo Millán-Zambrano (460604)

“…<p><b>A.</b> Comparative distribution of total RNA polymerase II (as measured by Rpb3 ChIP) and active transcription (as measured by run-on) across genes, expressed as 3′/5′ ratios. …”

OVX educes bone density of femur. by Mingzhu Chen (6370013)

“…Compared to Sham rats, OVX tats had a significant decrease in bone mass and impaired bone micro structure: (L) BMD, (M) BV, (N) BV/TV, (O) Tb.N,(P) Tb.Sp, and (Q) Tb.Th. …”

Mechanism of astrocyte regulation of synaptic release. by Maurizio De Pittà (194237)

“…<p>(<b>A</b>, <i>top</i>) When intracellular Ca²⁺ increases beyond the threshold value for exocytosis (<i>dashed red line</i>), the astrocyte releases an amount of glutamate into the extrasynaptic space (<i>black mark</i>, <i>middle</i>). …”

Data_Sheet_1_Stable Soil Microbial Functional Structure Responding to Biodiversity Loss Based on Metagenomic Evidences.DOCX by Huaihai Chen (5583182)

“…Our results showed that although biodiversity loss caused a decrease in taxonomic species by 72%, the changes in the relative abundance of diverse functional categories were limited. …”

Changes in functional microbiome expression across time. by Steven D. Hicks (5532734)

“…<b>(B)</b> A partial least squares discriminant analysis utilizing mean abundance levels for all 202 KEGG/COG metabolic pathways with microbial RNA mappings is displayed for the four collection time periods. …”

IL-32 was unable to induce the maturation of osteoclasts <i>in vitro</i>. by Guillaume Mabilleau (585064)

“…However, sRANKL-treatment of PBMCs resulted in a 43.3±9.8% percentage area resorption. Combined treatment of sRANKL and IL-32 resulted in a significant decrease of 2.6 fold in percentage area resorption compared to sRANKL alone. …”

CA and HT abolished the <i>in vivo</i> obesogenic effect of RGZ. by Esmail Lutfi (848005)

“…Exposure to 1 μM RGZ induced a significantly smaller decrease in adiposity compared with CT. …”

Quantification of ECS component immunoreactivity in the colonic epithelium. by Lucia Marquéz (5650663)

“…<p>A: Untreated acute UC at disease onset showed increases in CB₂, DAGLα and MAGL immunoreactivity, and decreases in NAPE-PLD immunostaining. …”

Platelets from hPAR1-KI mice exhibit diminished responses to thrombin. by Shauna L. French (3279633)

“…<p>Platelets isolated from <b>(A,D)</b> hPAR1-KI mice, <b>(B,E)</b> wild type mice, or <b>(C,F)</b> humans were with thrombin and examined for <b>(A-C)</b> platelet aggregation by light transmission aggregometry or <b>(D-F)</b> P-selectin expression by flow cytometry. …”

Immunofluorescence, gene expression, and Western blot analysis of BMP-2 of chondrocytes cultured at 1 <i>g</i> or on the RPM. by Ganna Aleshcheva (429382)

“…<b>G:</b> Western blot analysis of BMP-2 protein revealed a decrease after 4 h and an increase after 24 h RPM exposure. …”