Evolutionary Consequences of Altered Atmospheric Oxygen in <em>Drosophila melanogaster</em> by Marc Charette (198776)

“…<div><p>Twelve replicate populations of <em>Drosophila melanogaster</em>, all derived from a common ancestor, were independently evolved for 34+ generations in one of three treatment environments of varying PO₂: hypoxia (5.0–10.1 kPa), normoxia (21.3 kPa), and hyperoxia (40.5 kPa). …”

Treatment of landfill leachate using Fenton Processes and Photo-Fenton Solar by Fábio Moraes da Costa (5376350)

“…These conditions led to a decrease in the toxicity of leachates' coefficient values to a degree equal to 50 % - for Aliivibrio fischeri greater than 50% - indicating a more suitable leachate for further biological treatment.…”

<i>Def6</i> RNA rescues the <i>def6</i> MO-induced phenotype. by Katerina Goudevenou (199855)

“…ANOVA single factor and two-tailed Student's <i>t</i>-tests showed a significant (p<0.001; three asterisks) increase in the angle after injection of 2.5 ng <i>def6</i> MO and a significant (p<0.001; three asterisks) decrease in the angle after addition of <i>def6</i> RNA. …”

Effect of ASM-024 on lung tissue resistance in response to methacholine. by Evelyne Israël Assayag (512451)

“…A single 5 minutes exposure to 1.5 mg/kg nebulized ASM-024 prior to the methacholine challenge significantly decreased airway resistance in OVA-sensitized mice; p<0.05 for 0.06, 0.125, 0.25 and 1 mg/kg methacholine (A). …”

Our motoneuron model demonstrates that synaptic input noise does not account for signal dependent noise in synaptic input. by Akira Nagamori (4743981)

“…Note that this relationship is expressed as <i>SD</i> ∝ <i>mean</i>^0.5. B) Motoneuron discharge rates as a function of synaptic currents with (blue line) and without hysteresis (orange line) in motoneuron discharges. …”

The F2-isoprostane approach allows for analysis of FOXO transcription factor control of endogenous oxidative stress. by Christiaan F. Labuschagne (485155)

“…DLD-1 and DL-23 cells were incubated with 4-OHT to activate FOXO3a for 24 hours, before treatment with PQ for another 8 hours. 5-iPF2α-VI levels were analyzed and data are represented as mean fold increase ± S.E.M (*p < 0.05, *** p < 0.001).…”

Effect of antenatal class attendance on fear of childbirth and antenatal stress by Selda Yörük (15298001)

“…Fear of childbirth score were not significantly different between the intervention group and the control group. The mean APSI score of pregnant women in the intervention group was 22.32 ± 6.12 before the training and 21.79 ± 5.97 after the training. …”

Activation of the UPR can override the inhibition of NF-κB by IKK inhibitors in cancer cells with elevated IKK activity. by Arvin B. Tam (124164)

“…A reduction in P-IκBα and increase in total IκBα were seen corresponding to a decrease in IKK activity. …”

Reconsolidation and extinction after different strengths of training. by Remus Osan (3639754)

“…Bars indicate freezing in vehicle (dark blue) and anisomycin (light blue) groups before (left set) and after (right set) reexposure with <i>t</i> = 4 (mean ± S.E.M. of 100 simulations). As occurs in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0023113#pone-0023113-g003" target="_blank">Figure 3C</a>, freezing is decreased by anisomycin administration, indicating reconsolidation blockade. …”

Expression of miR-202-3p and its target Sufu mRNA in CLL cells. by Mosavar Farahani (819379)

“…<p><b>(A)</b> HS-5 cells incubated with MEC-1 exosomes for 24 hrs show increased expression of miR-202-3p by RT-qPCR analysis. …”

Automated gait analysis reveals early signs of motor defects in <i>Mecp2^stop/y</i> mice. by Kamal K. E. Gadalla (659748)

“…<i>Mecp2^stop/y</i> mice show a gradual phenotype score progression that is significantly different from WT (WT n = 7; <i>Mecp2^stop/y</i> n = 8 at 3–7 weeks, n = 7 at week 8, n = 5 at week 9 and n = 4 at week 10); decreasing numbers of <i>Mecp2^stop/y</i> mice are explained by early death of some mutant mice. …”

Extreme Low-Temperature Combustion Chemistry: Ozone-Initiated Oxidation of Methyl Hexanoate by Aric C. Rousso (5872646)

“…The accelerating chemical effect of ozone addition on the oxidation chemistry of methyl hexanoate [CH₃(CH₂)₄C­(O)­OCH₃] was investigated over a temperature range from 460 to 940 K. Using an externally heated jet-stirred reactor at <i>p</i> = 700 Torr (residence time τ = 1.3 s, stoichiometry φ = 0.5, 80% argon dilution), we explored the relevant chemical pathways by employing molecular-beam mass spectrometry with electron and single-photon ionization to trace the temperature dependencies of key intermediates, including many hydroperoxides. …”

Pre-seeded scaffolds promote more effective tissue regeneration. by Paul P. Bonvallet (708039)

“…*Represents p<0.01 for all treatment groups that are significantly different from each other within the same time point. Also, all treatment groups significantly decreased over time (p<0.001).…”

The effect of dopamine on Δψ_m and [Ca²⁺]_c in midbrain neurons and astrocytes. by Sonia Gandhi (49260)

“…Figure bi demonstrates the increase in Rh123 fluorescence at 1 minute, 6 minutes and 12 minutes that reflects mitochondrial membrane depolarisation in PINK1 ko cells. c, d: Single cell traces of PINK1 ko neurons demonstrating that dopamine induced decrease in ΔΨ_m occurs independently of any change in [Ca²⁺]_c in some cells (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037564#pone-0037564-g001" target="_blank">Figure 1c</a>), whereas in other cells dopamine induced decrease in ΔΨ_m co-incides with a rise in [Ca²⁺]_c (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037564#pone-0037564-g001" target="_blank">Figure 1d</a>). e: Incubation with D1/D5 receptor antagonist SCH23390 (20 µM) did not alter the dopamine induced calcium signal or mitochondrial depolarisation in PINK1 ko neurons. f: Dopamine induced mitochondrial depolarisation was prevented by application of the PTP inhibitor 1 µM cyclosporine A.…”

Elimination testing with adapted scoring reduces guessing and anxiety in multiple-choice assessments, but does not increase grade average in comparison with negative marking by Jef Vanderoost (5108072)

“…The comparison is structured around seven hypotheses: in comparison with negative marking, elimination testing with adapted scoring leads to (1) a similar average score (no grade inflation); (2) students expressing their partial knowledge; (3) a decrease in the number of blank answers; (4) no gender bias in the number of blank answers; (5) a reduction in guessing; (6) a decrease in self-reported test anxiety; and finally (7) students preferring elimination testing with adapted scoring over negative marking.…”

Downregulation of COP9 signalosome subunits differentially affects the CSN complex and target protein stability-0 by Andreas Peth (85734)

“…Whereas the anti-CSN5 antibody revealed a reduction to 23% as compared to the control, there was no decrease of the CSN complex observed with the anti-CSN8 antibody. …”

Physical activity levels determine exercise-induced changes in brain excitability - Fig 3 by Tea Lulic (3369371)

“…<p>SICI: (A) Group-averaged unconditioned MEPs (i.e. MEP_TS) (with standard errors) for both groups (LOW: N = 13; HIGH: N = 11) at both time points. …”

Ras transformation affects the circadian clock via MAPK signalling. by Angela Relógio (193817)

“…(<b>B</b>) Western Blot analysis of RAS protein expression for the HaCaT cell lines and its derivatives (HaCaTI7, HaCaTII4, A5RT3), shows clear RAS overexpression measured in A5RT3. …”

Behavioral Logic for Operant Training and Discrimination Testing by Samar B Mehta (274037)

“…As this behavior was established, <i>N</i> was increased from 0.063 s to 1.5 s.</p> <p>(C) Stimulus training. All trials in this stage were initiated by a 1.5-s nose poke. …”

Apocynin restores vasorelaxation of the diabetic aorta. by Sachin Gupte (363123)

“…</b> Diabetes did not alter the response to SNAP (a nitric oxide donor). Values are mean±SEM of 5 animals. * p<.05 compared to Wistar.…”