Supplementary Material for: Lobar Quantification by Ventilation/Perfusion SPECT/CT in Patients with Severe Emphysema Undergoing Lung Volume Reduction with Endobronchial Valves by Kristiansen J.F. (6802865)

“…V/Q SPECT/CT-assessed volume of the targeted lobe decreased by a mean of –395 mL and a relative mean of –26.8%, whilst ventilation and perfusion decreased by a relative mean of –37.1 and –25.7%. …”

The effect of dopamine on Δψ_m and [Ca²⁺]_c in midbrain neurons and astrocytes. by Sonia Gandhi (49260)

“…Figure bi demonstrates the increase in Rh123 fluorescence at 1 minute, 6 minutes and 12 minutes that reflects mitochondrial membrane depolarisation in PINK1 ko cells. c, d: Single cell traces of PINK1 ko neurons demonstrating that dopamine induced decrease in ΔΨ_m occurs independently of any change in [Ca²⁺]_c in some cells (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037564#pone-0037564-g001" target="_blank">Figure 1c</a>), whereas in other cells dopamine induced decrease in ΔΨ_m co-incides with a rise in [Ca²⁺]_c (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0037564#pone-0037564-g001" target="_blank">Figure 1d</a>). e: Incubation with D1/D5 receptor antagonist SCH23390 (20 µM) did not alter the dopamine induced calcium signal or mitochondrial depolarisation in PINK1 ko neurons. f: Dopamine induced mitochondrial depolarisation was prevented by application of the PTP inhibitor 1 µM cyclosporine A.…”

Elimination testing with adapted scoring reduces guessing and anxiety in multiple-choice assessments, but does not increase grade average in comparison with negative marking by Jef Vanderoost (5108072)

“…The comparison is structured around seven hypotheses: in comparison with negative marking, elimination testing with adapted scoring leads to (1) a similar average score (no grade inflation); (2) students expressing their partial knowledge; (3) a decrease in the number of blank answers; (4) no gender bias in the number of blank answers; (5) a reduction in guessing; (6) a decrease in self-reported test anxiety; and finally (7) students preferring elimination testing with adapted scoring over negative marking.…”

Inhibition of autophagy potentiates the response to chemotherapy only in the spheroids sensitive to GDC-0980. by Dario Barbone (111176)

“…<p>(A) M28 and REN spheroids were transfected with ATG5 (left panels) and ATG7 siRNA (right panels) and treated with GDC-0980 (1 μM), bortezomib (25 nM), ammonium chloride (NH₄⁺, 10 mM) or the combination for 6 h. …”

Pial arteriolar dilatory responses to ACh and NMDA are significantly impaired during ECM and can be partially restored by BH4 supplementation. by Peng Kai Ong (424201)

“…<p><b>A</b>: Mean arteriolar vessel diameters before compound superfusion in all studies. …”

Ras transformation affects the circadian clock via MAPK signalling. by Angela Relógio (193817)

“…(<b>B</b>) Western Blot analysis of RAS protein expression for the HaCaT cell lines and its derivatives (HaCaTI7, HaCaTII4, A5RT3), shows clear RAS overexpression measured in A5RT3. …”

Behavioral Logic for Operant Training and Discrimination Testing by Samar B Mehta (274037)

“…As this behavior was established, <i>N</i> was increased from 0.063 s to 1.5 s.</p> <p>(C) Stimulus training. All trials in this stage were initiated by a 1.5-s nose poke. …”

Data Sheet 1_Diagnostic utility of hematological and biochemical markers for cystic echinococcosis in Tibetan patients of Sichuan, China.pdf by Meng Ma (2075878)

“…</p>Results<p>(1) Patients with CE displayed significant abnormalities in blood and biochemical indicators compared to healthy subjects, including increased levels of platelet count, eosinophil percentage, basophil percentage, prothrombin time, fibrinogen, activated partial thromboplastin time, total bilirubin, direct bilirubin, γ-glutamyltransferase, aspartate aminotransferase, and alkaline phosphatase. Conversely, there was a decrease in lymphocyte percentage, hemoglobin concentration, mean corpuscular volume, and hematocrit. (2) Prothrombin time levels were markedly elevated beyond normal reference values, with prolonged prothrombin time identified as a significant predictor for CE. (3) The area under the receiver operating characteristic curve (AUC) for predicting CE based on prothrombin time was 0.969, while the AUC for predicting CE using a combination of prothrombin time and eosinophil percentage was 0.982.…”

Video_1_Robustness and Scalability of Regional Climate Projections Over Europe.mp4 by Dominic Matte (6270914)

“…<p>Climate change projections for Europe consistently indicate a future decrease in summer precipitation over southern Europe and an increase over northern Europe. …”

<i>In vitro</i> effect of c-myc overexpression on <i>EBI3</i> expression level. by Julie Gonin (344703)

“…The expression of <i>EBI3</i> in c-myc-ER transfected cells relative to that measured in control tranfected cells is represented. The percentage of decrease is indicated. A higher concentration of 4-OHT (1 µM) did not result in higher repression of <i>EBI3</i> expression (not shown). …”

The mRNA levels of GLUT-1 were reduced with FIH-1 overexpression. by Enfeng Wang (215932)

“…The data here is the mean from three independent results. * Represents p value less than 0.05. 1C and 1D: The expression levels of GLUT-1 were decreased by overexpression of FIH-1 in U87 cells. …”

Slug's regulatory targets: by Chi Zhang (9857)

“…<p>A: In animal caps analyzed at stage 11, the Slug MO (10 ng/embryo) produced a decrease in RelA RNA levels that was rescued by co-injection of mycGFP-Slug RNA (1 ng/embryo). …”

Early-age-related changes in proteostasis induce inflammation. by Manish Bodas (191021)

“…The bottom panel (A & B) shows the densitometric analysis of VCP expression in both lung and liver normalized to β-actin (Mean ± SEM, n = 3, *p<0.05). …”

Video_2_Robustness and Scalability of Regional Climate Projections Over Europe.MP4 by Dominic Matte (6270914)

“…<p>Climate change projections for Europe consistently indicate a future decrease in summer precipitation over southern Europe and an increase over northern Europe. …”

The effect of extracellular glucose on the protein levels of ABCC11. by Yu Toyoda (2826734)

“…<p>(A and B) The decrease of the glycosylation and the protein levels of ABCC11 wild-type (WT) expressed in MDCKII cells cultured with a low-glucose medium. …”

Characterization of induction dose-response and dynamics for bicistronic autoregulation circuit. by Zach Hensel (242038)

“…Cells grown in 16 nM ATc were washed starting at at t = –10 min and observed starting at t = 0 min. The decrease in fluorescence from t = 10 min to t = 120 min is well fit by exponential decay with a half-time of 64.1 min.…”

Yeast lacking both SAS-I and Esa1 show no detectable H4 K16Ac. by Mark Boltengagen (10833845)

“…<p>(A) Absence of Sas2 caused a further decrease of viability in <i>esa1Δ sds3Δ</i> cells. …”

Physical activity levels determine exercise-induced changes in brain excitability - Fig 3 by Tea Lulic (3369371)

“…<p>SICI: (A) Group-averaged unconditioned MEPs (i.e. MEP_TS) (with standard errors) for both groups (LOW: N = 13; HIGH: N = 11) at both time points. …”

Prevention of oral cancer by Malki, Ahmed Mohamed

“…Oral cancer is typically discovered late in its development, most often when it has already metastasized to the lymph nodes, at which point prognosis becomes very poor. Therefore, we firmly believe that it is no longer viable that prevention be considered a person’s own responsibility but rather a matter of a group of health professionals. …”
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DataSheet_1_Membrane estrogen receptor-α contributes to female protection against high-fat diet-induced metabolic disorders.pdf by Aurélie Fabre (288323)

“…</p>Methods<p>Male and female C451A-ERα mice, harboring a point mutation which results in the abolition of membrane localization and MISS-related effects of the receptor, and their wild-type littermates (WT-ERα) were maintained on a normal chow diet (NCD) or fed a high-fat diet (HFD). …”