Immune Checkpoint Inhibitors and Risk of Type 1 Diabetes by Xuan Chen (158617)

“…Younger age (HR=1.19 for every 5-year decrease; 95% CI, 1.13-1.25) and pre-existing non-T1DM diabetes (HR=4.48; 95% CI, 3.45-5.83) were also associated with higher risk of ICI-T1DM. …”

Table 4_The burden and etiologies of diarrhea in Asia and its countries from 1990 to 2021 and the forecast to 2040: analyses informed by the global burden of disease study 2021.doc... by Shan Liu (193759)

“…</p>Results<p>Overall burden showed that the ASRs in Asia decreased from 1990 to 2021, with EAPCs of −0.40, −0.55, −5.70, and −5.47, respectively. …”

Thermal Manipulation during Embryogenesis Has Long-Term Effects on Muscle and Liver Metabolism in Fast-Growing Chickens by Thomas Loyau (624425)

“…The aim of this study was to evaluate the long-term effects of TM (12 h/d, 39.5°C, 65% RH from d 7 to 16 of embryogenesis vs. 37.8°C, 56% RH continuously) and of a subsequent heat challenge (32°C for 5 h at 34 d) on the mRNA expression of metabolic genes and cell signaling in the <i>Pectoralis major</i> muscle and the liver. …”

DataSheet1_Gravity-Vector Induces Mechanical Remodeling of rMSCs via Combined Substrate Stiffness and Orientation.docx by Chen Zhang (66790)

“…Moreover, cellular morphology and focal adhesion were mainly affected by substrate stiffness, yielding a time course of increased spreading area at 24 h but decreased area at 72 h with a decrease of stiffness. …”

Nephroprotective Efficacy of RAS Blockade in Mice Carrying R140Q Podocin Mutation by Helga Denc (567951)

“…</p> <p>RESULTS:Induction of R140Q-podocin hemizygosity caused massive proteinuria peaking at 4 wks,followed by a gradual decrease as progressive renal failure developed.In the P animals,RAS blockade persistently inhibited proteinuria(13%of untreated animals at 4 wks,p<0.005).In the D group,proteinuria sharply decreased upon RAS blockade.Three-month survival was 31% in the untreated,67% in the D and 100% in the P group respectively(p<0.05).…”

DataSheet_1_The efficacy and safety of short-term and low-dose IL-2 combined with tocilizumab to treat rheumatoid arthritis.docx by Sheng-Xiao Zhang (8832449)

“…The low-dose IL-2 and combination treatment groups demonstrated a violent proliferation of Tregs, while the absolute number of Th1, Th2, and Th17 cells in the latter group showed a decreasing trend. …”

Table 3_The burden and etiologies of diarrhea in Asia and its countries from 1990 to 2021 and the forecast to 2040: analyses informed by the global burden of disease study 2021.doc... by Shan Liu (193759)

“…</p>Results<p>Overall burden showed that the ASRs in Asia decreased from 1990 to 2021, with EAPCs of −0.40, −0.55, −5.70, and −5.47, respectively. …”

Flowchart of the included study population. by Tim Alex Lindskou (6411278)

“…Frequency of chest pain patients and AMI increased 255 and 22 patients per year respectively, whereas the AMI proportion remained statistically stable, with a tendency towards a decrease in the last years. …”

Inhibition of ER-β abolishes the sex differences in Na⁺ transport and female FDLE cells are more responsive to E2 stimulation. by Till Kaltofen (785354)

“…<p>(A) I_base and I_amil were significantly higher in FDLE cells of female origin, while PHTPP abolished the sex difference (n = 23–28; mean + SEM; *p<0.05; **p<0.01 by T-test). …”

TAT-Ahx-AKAPis significantly reduced microvascular endothelial barrier function and reverted F/R- mediated barrier stabilization. by Mariya Y. Radeva (625707)

“…(B) summarizes the results after 600 min, the time point at which the monitored effects reached their peaks. …”

Summary of the hypothetical GBM cell responses to the niche. by Francesca Pistollato (262196)

“…Moreover, HIF-1α inhibits SMAD1/5/8 activation <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0006206#pone.0006206-Pistollato1" target="_blank">[3]</a>. …”

Prb1 overexpression promoted APC entry into vacuoles in <i>vps21Δ</i> cells (but not in <i>ypt1ts</i> and <i>ypt7Δ</i> cells) after nitrogen starvation. by Zulin Wu (4451572)

“…<p><b>A.</b> The accumulation of GFP-Atg8-labeled APCs in <i>vps21Δ</i> cells decreased after Prb1 overexpression. …”

Phenotype of mutants for housekeeping genes are similar and depend on p53 network upregulation. by Nadia Danilova (186070)

“…<p><b>A–C</b>) Excessive neural apoptosis was manifested as gray areas in the brain at 24 hpf, which was rescued by p53 inhibition <b>D–F</b>) At 48 hpf, there were more apoptotic cells in mutants compared to siblings and p53 inhibition led to a decrease in apoptosis. …”

Degradation Pathways of Ataxin-3-Induced Neurodegeneration by Julide Bilen (35807)

“…Genotypes (B) <i>EP1384; gmr-GAL4 UAS-SCA3trQ78 /+; UAS-DTS5/+</i> and (C) <i>w; gmr-GAL4 UAS-SCA3trQ78/+; UAS-DTS5/E213-1A.…”

B cells following CY treatment. by Daisuke Kawabata (198993)

“…The B cell numbers from individual mice is represented. A significant decrease in total B cell numbers in both the BALB/c WT mice as well as the BALB/c R4A Tg mice following CY treatment was observed at all time points analyzed, but was near normal by day 28. …”

Withdrawal ratios by state. by Robert I. McDonald (260416)

“…Data points are labeled using the standard two-digit abbreviation for US states (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0065589#pone-0065589-g003" target="_blank">Figure 3</a>), staggered so that labels do not overlap.…”

Aging and long gene expression by Olga Ibanez Sole (5674514)

“…<p>In this repository, we provide the notebooks necessary to reproduce the analyses decribed in the article <em>Age or lifestyle-induced accumulation of genotoxicity is associated with a length-dependent decrease in gene expression. …”

The changes of urinary levels of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). by Yuan-Hong Jiang (398786)

“…<p>The urinary levels of NGF (pg/ml) and BDNF (pg/ml) were compared between baseline and after 6-month treatment of HA (6M) in responders and non-responders based on (A) a visual analogue scale (VAS, for pain) decrease of ≥ 2, (B) global response assessment (GRA) increase of ≥ 2 and (C) functional bladder capacity (FBC) increase of ≥ 50%. …”

Image 3_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.tif by Stefanie Wagner (743707)

“…In contrast, analysis of relative abundances only showed a decrease of Faecalibacterium and Rikenellaceae RC9 gut group and, thus, a much less detailed antibiotic effect.…”

Image 1_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.tif by Stefanie Wagner (743707)

“…In contrast, analysis of relative abundances only showed a decrease of Faecalibacterium and Rikenellaceae RC9 gut group and, thus, a much less detailed antibiotic effect.…”