Image_1_Soluble Programmed Death Receptor Ligands sPD-L1 and sPD-L2 as Liquid Biopsy Markers for Prognosis and Platinum Response in Epithelial Ovarian Cancer.TIF by Paul Buderath (560824)

“…High sPD-L1 levels were associated with a reduced 5 year overall survival (OS, p = 0.003) and progression-free survival (PFS, p = 0.019). …”

Contribution of factor H-Binding protein sequence to the cross-reactivity of meningococcal native outer membrane vesicle vaccines with over-expressed fHbp variant group 1 by Arianna Marini (4275988)

“…The work reinforces that meningococcal NOMV with OE fHbp is a promising vaccine strategy, and provides a basis for rational selection of antigen sequence types for over-expression on NOMV.…”

Datafiles and R script for analyses and figures for submitted manuscript titled: Loss of dominant tree-mycorrhizal mutualism increases soil fungal diversity and alters community st... by Lindsay McCulloch (8565423)

“…The varition in pH among treatments, likely driven by tannic acid in oak leaves, and the effect of pH on fungal diversity highlight the complex feedbacks and co-determined successional dynamics of the tree and fungal communities.</p><p dir="ltr">5. Synthesis: Here we show that the removal of a dominant plant species, such as oaks in the northeastern US, can have casacading effects on the soil microbial community composition. …”

DataSheet1_The systematic review and meta-analysis evaluated the efficacy and safety of nefopam for catheter-related bladder discomfort based on randomized controlled trials.PDF by Junpeng Chi (17445264)

“…Data analysis was performed using RevMan version 5.4.1.</p><p>Results: Five RCTs with 405 patients were analyzed to evaluate the efficacy of nefopam on postoperative CRBD. …”

Image_2_An updated management approach of Pompe disease patients with high-sustained anti-rhGAA IgG antibody titers: experience with bortezomib-based immunomodulation.jpeg by Ankit K. Desai (9214082)

“…</p>Methods<p>Here, we describe two IOPD cases (patients 6 and 8) who developed HSAT at 8 and 10 weeks on ERT despite transient low-dose methotrexate ITI administration in the ERT-naïve setting and were treated with a bortezomib-based ITI regimen, and we compare their courses to a series of six historical patients (patients 1-5, and 7) with a similar presentation who exemplify our evolving approach to treatment.…”

Secondary structure in the conserved C-terminal region is responsible for the CAHS filament formation and gelation. by Akihiro Tanaka (342394)

“…<p>(A) Schematic diagrams of CAHS3 proteins. “CR1” and “CR2” indicate putative helical motifs highly conserved among almost all CAHS family members. …”

Image_1_An updated management approach of Pompe disease patients with high-sustained anti-rhGAA IgG antibody titers: experience with bortezomib-based immunomodulation.jpeg by Ankit K. Desai (9214082)

“…</p>Methods<p>Here, we describe two IOPD cases (patients 6 and 8) who developed HSAT at 8 and 10 weeks on ERT despite transient low-dose methotrexate ITI administration in the ERT-naïve setting and were treated with a bortezomib-based ITI regimen, and we compare their courses to a series of six historical patients (patients 1-5, and 7) with a similar presentation who exemplify our evolving approach to treatment.…”

Image_3_An updated management approach of Pompe disease patients with high-sustained anti-rhGAA IgG antibody titers: experience with bortezomib-based immunomodulation.png by Ankit K. Desai (9214082)

“…</p>Methods<p>Here, we describe two IOPD cases (patients 6 and 8) who developed HSAT at 8 and 10 weeks on ERT despite transient low-dose methotrexate ITI administration in the ERT-naïve setting and were treated with a bortezomib-based ITI regimen, and we compare their courses to a series of six historical patients (patients 1-5, and 7) with a similar presentation who exemplify our evolving approach to treatment.…”

Supporting data for "DECODING THE NEUROIMMUNE AXIS OF HEAD AND NECK CANCER TO ENHANCE IMMUNOTHERAPEUTIC OUTCOMES" by Ravi Kishan (11263155)

“…Genetic ablation of PTHLH resulted in dysregulation of neurotrophic signaling pathways essential for intra-tumoral innervation, significant reduction in tumor burden, and enhanced antitumor immunity —evidenced by increased CD8+ and CD4+ T cell infiltration, as well as decreased immunosuppressive markers. These findings establish the tumor-derived neuropeptide PTHLH as a critical regulator of the neuroimmune axis in HNSCC.…”

Ion-Pair Charge-Transfer Complexes Based on (<i>o</i>-Phenylenebis(oxamato))cuprate(II) and Cyclic Diquaternary Cations of 1,10-Phenanthroline and 2,2‘-Bipyridine:  Synthesis, Crys... by Iosu Unamuno (2977419)

“…Crystal data for the compounds <b>1</b>, <i>a</i> = 7.3216(13) Å, <i>b</i> = 10.1756(9) Å, <i>c</i> = 16.4890(16) Å, α = 107.786(8)°, β = 94.79(1)°, γ = 104.16(1)°, <i>V</i> = 1117.4(3) ų, <i>Z</i> = 2, <i>R</i> = 0.033 for 5332 observed reflections with <i>I</i> > 3σ(I); <b>2</b>, <i>a</i> = 6.732(3) Å, <i>b</i> = 11.169(3) Å, <i>c</i> = 12.126(2) Å, α = 111.01(2)°, β = 102.71(3)°, γ = 93.57(3)°, <i>V</i> = 820.1(5) ų, <i>Z</i> = 2, <i>R</i> = 0.065 for 3354 observed reflections with <i>I</i> > 3σ(<i>I</i>). …”

Ion-Pair Charge-Transfer Complexes Based on (<i>o</i>-Phenylenebis(oxamato))cuprate(II) and Cyclic Diquaternary Cations of 1,10-Phenanthroline and 2,2‘-Bipyridine:  Synthesis, Crys... by Iosu Unamuno (2977419)

“…Crystal data for the compounds <b>1</b>, <i>a</i> = 7.3216(13) Å, <i>b</i> = 10.1756(9) Å, <i>c</i> = 16.4890(16) Å, α = 107.786(8)°, β = 94.79(1)°, γ = 104.16(1)°, <i>V</i> = 1117.4(3) ų, <i>Z</i> = 2, <i>R</i> = 0.033 for 5332 observed reflections with <i>I</i> > 3σ(I); <b>2</b>, <i>a</i> = 6.732(3) Å, <i>b</i> = 11.169(3) Å, <i>c</i> = 12.126(2) Å, α = 111.01(2)°, β = 102.71(3)°, γ = 93.57(3)°, <i>V</i> = 820.1(5) ų, <i>Z</i> = 2, <i>R</i> = 0.065 for 3354 observed reflections with <i>I</i> > 3σ(<i>I</i>). …”

Data_Sheet_1_Occurrence of Strongylid Nematode Parasites on Horse Farms in Berlin and Brandenburg, Germany, With High Seroprevalence of Strongylus vulgaris Infection.PDF by Laura Jürgenschellert (9363453)

“…On the farm level, prevalence for Strongylus spp. by PCR was 12.5%. Applying a conservative cut-off (sensitivity 0.43, specificity 0.96), 21.2% of all serum samples were positive for antibodies against S. vulgaris larvae (83.3% prevalence on farm level). …”

Datasheet1_Comparison of effective regurgitant orifice area by the PISA method and tricuspid coaptation gap measurement to identify very severe tricuspid regurgitation and stratify... by Yohann Bohbot (10860003)

“…. ≥60 mm² (68 ± 3% vs. 64 ± 5%, p = 0.89). A TCG ≥10 mm was associated with lower four-year survival than a TCG <10 mm (53 ± 7% vs. 69 ± 3%, p < 0.001). …”

Protein restricted diet during gestation and/or lactation in mice affects ¹⁵N natural isotopic abundance of organs in the offspring: Effect of diet ¹⁵N conten... by Karine Bernardo (5843759)

“…Growth rate did not differ between groups after 10 days and decreased between 1 and 5 months. ¹⁵N NIA differed between organs and was affected by growth and gestation/lactation.…”

CHW characteristics at baseline. by Josephine Pascal Ferla (16024506)

“…Male participation increased in home observation sessions from 5.6% at baseline to 17.6% at endline (p < .0001).…”

Table2_Clinical Evidence-Guided Anti-rheumatoid Arthritis Study of Shuji Tablet in Adjuvant-Induced Arthritis Rats and Mechanism Exploration via Network Pharmacological Approach.XL... by Weibo Dai (11201244)

“…The mechanism exploration and target prediction of SJT against RA were performed via a network pharmacological approach.</p><p>Results: SJT showed excellent alleviation on AIA rats, with evidence of reducing paws swelling, decreasing systemic symptoms score, and arthritis index. …”

Assessment of mirvetuximab soravtansine immunogenicity in patients with folate receptor alpha-positive ovarian cancer by Fengying Zhu (19818810)

“…</p> <p>Mirvetuximab soravtansine (MIRV) is a new drug of cancer treatment that targets a protein called folate receptor alpha, which is often found in certain ovarian cancers that do not respond to platinum-based therapies. …”

Table_1_Clara Cell 10 kDa Protein Alleviates Murine Hepatitis Virus Strain 3-Induced Fulminant Hepatitis by Inhibiting Fibrinogen-Like Protein 2 Expression.DOC by Haijing Yu (234338)

“…<p>Background: Fulminant hepatitis (FH) is a serious threat to human life, accompanied by massive and rapid necroinflammation. …”

Table2_Clinical Evidence-Guided Anti-rheumatoid Arthritis Study of Shuji Tablet in Adjuvant-Induced Arthritis Rats and Mechanism Exploration via Network Pharmacological Approach.XL... by Weibo Dai (11201244)

“…The mechanism exploration and target prediction of SJT against RA were performed via a network pharmacological approach.</p><p>Results: SJT showed excellent alleviation on AIA rats, with evidence of reducing paws swelling, decreasing systemic symptoms score, and arthritis index. …”

Spatiotemporal release of DZNep and gemcitabine using engineered nanoparticles reduced drug dose while potentiating chemosensitivity. by Sau Wai Hung (102677)

“…Twenty-four hours after 5×10³ cells/well were seeded in a 96-well plate, cells were treated for 72 h. …”