Identification of suitable reference genes for real-time qPCR in homocysteine-treated human umbilical vein endothelial cells by Xia Zhu (396327)

“…Surprisingly, the <i>β-actin</i> (<i>ACTB</i>) levels decreased significantly in Hcy-treated HUVECs compared with control HUVECs (<i>P</i><0.05), and further study indicated that Hcy suppressed the expression of <i>ACTB</i> by upregulating the miR-145-5p level in Hcy-treated HUVECs. …”

DataSheet_1_Seasonal approach to forecast the suitability of spawning habitats of a temperate small pelagic fish under a high-emission climate change scenario.pdf by André R. A. Lima (6684476)

“…<p>Spawning habitats of cold-water, European small pelagic fishes have shifted poleward in the last three decades coincident with gradual ocean warming. We predicted present-day, season-specific habitat suitability for spawning by European sardine Sardina pichardus in the Atlantic Ocean and Mediterranean and Black Seas, and projected climate-driven changes in suitable areas from 2050-2099 under the IPCC – RCP 8.5 scenario. …”

The Transcription Factor MAZR Preferentially Acts as a Transcriptional Repressor in Mast Cells and Plays a Minor Role in the Regulation of Effector Functions in Response to FcεRI S... by Anastasia Abramova (473309)

“…To study the role of MAZR in mast cells, we generated a conditional <i>Mazr</i> allele and crossed <i>Mazr</i>^F/F mice with the <i>Vav-iCre</i> deleter strain, which is active in all hematopoietic cells. …”

DataSheet_2_Seasonal approach to forecast the suitability of spawning habitats of a temperate small pelagic fish under a high-emission climate change scenario.pdf by André R. A. Lima (6684476)

“…<p>Spawning habitats of cold-water, European small pelagic fishes have shifted poleward in the last three decades coincident with gradual ocean warming. We predicted present-day, season-specific habitat suitability for spawning by European sardine Sardina pichardus in the Atlantic Ocean and Mediterranean and Black Seas, and projected climate-driven changes in suitable areas from 2050-2099 under the IPCC – RCP 8.5 scenario. …”

Temporal trends in lung cancer survival: a population-based study by Lukas Löfling (7119512)

“…We used population-based information available in a national lung cancer research database (LCBaSe) generated by cross-linkage between the Swedish National Lung Cancer Register and several Swedish health and sociodemographic registers.…”

Reactive oxygen species from mitochondria impacts trophoblast fusion and the production of endocrine hormones by syncytiotrophoblasts by O’Llenecia S. Walker (8486163)

“…Increased mitochondrial ROS resulted in a significant decrease in the transcripts which encode for proteins associated with fusion (<i>GCM1</i>, <i>ERVW-1</i>, and <i>ERVFRD-1</i>) resulting in a 5-fold decrease in the percentage of BeWo fusion. …”

Estimating Sampling Selection Bias in Human Genetics: A Phenomenological Approach by Davide Risso (811836)

“…When taking into account only one individual per surname (low kinship model), the average discrepancy was 59.5%, with a peak of 84% by random sampling. When multiple individuals per surname were considered (high kinship model), the discrepancy decreased by 8–30% at the cost of a larger variance. …”

DataSheet_1_Prophylactic treatment of Glycyrrhiza glabra mitigates COVID-19 pathology through inhibition of pro-inflammatory cytokines in the hamster model and NETosis.pdf by Zaigham Abbas Rizvi (6167057)

“…Though vaccinations have proved effective in reducing the COVID-19-related mortality, the limitation of the use of vaccine against immunocompromised individuals, those with comorbidity, and emerging variants remains a concern. In the current study, we investigate for the first time the efficacy of the Glycyrrhiza glabra (GG) extract, a potent immunomodulator, against SARS-CoV-2 infection in hamsters. …”

Temporal and spatial modulation of the tumor and systemic immune response in the murine Gl261 glioma model by Kelly J. McKelvey (5638448)

“…<div><p>Glioblastoma, the most aggressive form of glioma, has a 5-year survival rate of <5%. While radiation and immunotherapies are routinely studied in the murine Gl261 glioma model, little is known about its inherent immune response. …”

A Single Mutation in Chikungunya Virus Affects Vector Specificity and Epidemic Potential by Konstantin A Tsetsarkin (78536)

“…</em> Using viral infectious clones of the Reunion strain and a West African strain of CHIKV, into which either the E1–226 A or V mutation was engineered, we demonstrated that the E1-A226V mutation was directly responsible for a significant increase in CHIKV infectivity for <em>Ae. albopictus</em>, and led to more efficient viral dissemination into mosquito secondary organs and transmission to suckling mice. …”

Reduced LFS-LTD but normal mGluR-LTD, HFS-LTP, TBS-LTP, and PSD density and morphology in the <i>Grin2b</i>^{<i>+/C456Y</i>} hippocampus. by Wangyong Shin (6793040)

Effect of TRPML1 on inflammation in lymphedema mice. by Lijie Yang (694492)

Diffusion tractography of the subcortical auditory system in a postmortem human brain by Kevin Sitek (4242859)

Osteoblast migration speed shows shear stress dependence but only for a short period after the onset of the flow. by Brandon D. Riehl (3749659)

“…<p>(a) MC3T3-E1 osteoblasts under fluid flows showed peak migration speeds after the flow onset, which then decreased. …”

Hydralazine treatment results in a reduction in tumor blood flow within 15 minutes. by Kate M. Bailey (678043)

“…Representative diagrams showing a decrease in tumor blood flow following hydralazine treatment. …”

Acoustic Divergence with Gene Flow in a Lekking Hummingbird with Complex Songs by Clementina Gonzalez (627306)

Image_1_Ophthalmic findings of congenital insensitivity to pain with anhidrosis with a novel neurotrophic tyrosine kinase receptor type 1 gene mutation: A case report.JPEG by Rong Zhu (172093)

“…<p>We report a case of congenital insensitivity to pain with anhidrosis (CIPA) with a novel neurotrophic tyrosine kinase receptor type 1 (NTRK1) gene mutation. …”

Spheroid size changes due to primary mucus reduction hits and mucus changes due to primary swell hits. by Pranjali Beri (14945400)

<b>Effect of a Dietary Intervention on Insulin Requirements and Glycemic Control in Type 1 Diabetes: </b><b>A 12-Week Randomized Clinical Trial</b> by Hana Kahleova (618836)

Counterion Blockade in a Heterogeneously Charged Single-File Water Channel by Shusong Zhang (470905)

“…We rationalize the ionic transport using 1D Kramers’ escape theory framework, which describes nonlinear ionic current and the impact of surface charge density on the <i>I</i>–<i>V</i> curves. …”