Image 2_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.tif by Zhuowen Hu (20431616)

“…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”

Table4_Assessment of CircRNA Expression Profiles and Potential Functions in Brown Adipogenesis.XLSX by Pengpeng Zhang (583380)

“…<p>Brown adipose tissue (BAT) is specialized for energy expenditure, thus a better understanding of the regulators influencing BAT development could provide novel strategies to defense obesity. …”

Data_Sheet_3_Intestinal Microbiota and Immune Modulation in Zebrafish by Fucoidan From Okinawa Mozuku (Cladosiphon okamuranus).XLSX by Wakako Ikeda-Ohtsubo (5780795)

“…Our current study provides the first insights into in vivo modulatory effects of fucoidan on microbiota and immune responses of unchallenged zebrafish, which underscores the potential of fucoidan to play a modulatory role in the diet–microbiota–host interplay.…”

Image_1_Multi-omics Analysis of Microenvironment Characteristics and Immune Escape Mechanisms of Hepatocellular Carcinoma.TIF by Wenli Li (337819)

“…<p>The immune environment in primary tumor has a profound impact on immunotherapy. However, the clinical relevance of immune environment in hepatocellular carcinoma (HCC) is largely unknown. …”

FigShare_Data HbO2 JoP 50 (KMG).xlsx by Kayla Garvey (22027559)

“…These results suggest that optimal Hb-O₂ affinity is greater in high-altitude deer mice, in association with a greater capacity to extract and consume O₂ in thermogenic tissues.…”

Plasmacytoid Dendritic Cell Dynamics Tune Interferon-Alfa Production in SIV-Infected Cynomolgus Macaques by Timothée Bruel (337070)

“…<div><p>IFN-I production is a characteristic of HIV/SIV primary infections. …”

Data_Sheet_1_Physiological strategies for handling summer water stress differ among co-existing species and between juvenile and mature trees.PDF by Kelsey Bryant (14324523)

“…The majority of carbon sequestered in a forest is in mature trees; therefore, direct canopy measurements comparing responses to climate in juvenile and mature trees would allow us to more accurately predict changes in ecosystem carbon uptake. …”

DataSheet_1_BRAFV600E Mutation-Responsive miRNA-222-3p Promotes Metastasis of Papillary Thyroid Cancer Cells via Snail-Induced EMT.pdf by Yuan Gao (159945)

“…Inhibition of miR-222-3p significantly suppressed the migration of B-CPAP and induced a mesenchymal-epithelial transition (MET) phenotype via the Snail transcription factor. …”

Image 1_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.tif by Zhuowen Hu (20431616)

“…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”

Image3_Inhibition of Gasdermin D-Mediated Pyroptosis Attenuates the Severity of Seizures and Astroglial Damage in Kainic Acid-Induced Epileptic Mice.TIF by Lu Xia (1509745)

“…</p><p>Conclusion: GSDMD-mediated pyroptosis is involved in the mechanism of kainic acid-induced seizures. Our study provides a new potential therapeutic target for seizure control.…”

Formation of Zn(II) and Cd(II) Coordination Polymers Assembled by Triazine-Based Polycarboxylate and <i>in-Situ</i>-Generated Pyridine-4-thiolate or Dipyridylsulfide Ligands: Obser... by Qilong Zhu (2048197)

“…Three novel coordination polymers, [Cd₅(HTTHA)₂(Hpt)₄(H₂O)]·4H₂O (<b>1</b>; H₆TTHA = 1,3,5-triazine-2,4,6-triamine hexaacetic acid, Hpt = pyridinium-4-thiolate), {[Cd₃(TTHA)(dps)(H₂O)₃]₂}·H₂O (<b>2</b>), and [Zn₃(TTHA)(dps)(H₂O)]·5H₂O (<b>3</b>; dps =4,4′-dipyridylsulfide), have been synthesized by the flexible hexapodal acid H₆TTHA and <i>in-situ</i>-generated Hpt and dps ligands from a 4,4′-dipyridyldisulfide (dpds) precursor through cleavage of both S–S and S–C(sp²) bonds and temperature-dependent chemical rearrangement under hydrothermal conditions. …”

Image_1_Calcium-Sensing Receptor Participates in High Glucose-Induced EndMT in Primary Human Aortic Endothelial Cells.JPEG by Cheng Yuan (160315)

“…The in vitro results showed that HG significantly inhibited the expression of CD31 and increased FSP1 and α-SMA in a concentration- and time-dependent manner. Moreover, CaSR was increased in HAECs after HG treatment. …”

Image_3_Intracellular Complement Component 3 Attenuated Ischemia-Reperfusion Injury in the Isolated Buffer-Perfused Mouse Heart and Is Associated With Improved Metabolic Homeostasi... by M-K. Torp (12332864)

Table 1_Altered brain functional network connectivity and topology in type 2 diabetes mellitus.doc by Weiwei Ni (9269921)

“…All participants underwent clinical, neuropsychological, and laboratory tests, followed by MRI examinations, including resting-state functional magnetic resonance imaging (rs-fMRI) and three-dimensional high-resolution T1-weighted imaging (3D-T1WI) on a 3.0 T MRI scanner. Post-image preprocessing, brain functional networks were constructed using the Dosenbach atlas and analyzed with the DPABI-NET toolkit through graph theory.…”

Image 2_Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling.jpeg by Yiwen Li (354034)

“…PI3K signaling pathway was identified as a central mediator of the microbiota interaction in DMIRI. …”

Phloroglucinol attenuates the 6-OHDA-mediated loss of antioxidant enzymes in SH-SY5Y cells and rat brains. by Junghwa Ryu (448435)

“…<p>(<b>A</b>) 50 µg of protein was added to 50 mM phosphate buffer (pH 7) containing 100 mM H₂O₂. …”

Mitochondrial function remains impaired in the hypertrophied right ventricle of pulmonary hypertensive rats following short duration metoprolol treatment by Amelia S. Power (6569951)

“…This study examined RV mitochondrial function and ADP transfer in PH animals advancing to right heart failure, and investigated a potential therapy with the specific β₁-adrenergic-blocker metoprolol. …”

<i>Helicobacter pylori</i> Cholesteryl α-Glucosides Contribute to Its Pathogenicity and Immune Response by Natural Killer T Cells by Yuki Ito (29604)

“…Phagocytosis and activation of dendritic cells were observed at similar degrees in the presence of wild-type <i>H. pylori</i> or variants harboring mutant forms of αCgT showing a range of enzymatic activity. However, cholesteryl α-glucosides were recognized by invariant natural killer T (<i>i</i>NKT) cells, eliciting an immune response <i>in vitro</i> and <i>in vivo</i>. …”

Long-Term Observations Reveal Enhanced Nighttime Formation of Nitrated PAHs Following Primary Emission Reduction by Xiaodi Shi (1542910)

“…∑₁₂NPAHs decreased by 89.2% (2350 pg m^–3 to 254 pg m^–3), a slower decline than that of ∑₁₆PAHs determined using the same samples. …”

Enols of Amides Activated by the 2,2,2-Trichloroethoxycarbonyl Group by Ahmad Basheer (1914646)

“…Intramolecular hydrogen bonds result in a very low δ(OH) and contribute to the stability of the enols and are responsible for the higher percentage of the <i>E</i>-isomers when Y = CO₂Me and the <i>Z</i>-isomers when Y = CN. …”