TarB interaction with the 5′ UTR of <i>tcpF</i>. by Evan S. Bradley (214029)

“…At the 4 h static time point of AKI induction a band corresponding to the molecular weight of TcpF-FLAG was detected with the anti-FLAG antibody. …”

The multimerization of <i>D4Z4</i> abrogates CTCF binding and insulation activity. by Alexandre Ottaviani (249884)

“…Histograms show the average percentage of eGFP positive cells from day 18 to day 29±S.D. shown by error bars, when <i>eGFP</i> expression reaches a plateau. In the different constructs containing <i>D4Z4</i> inserted at random sites (C4X, C8X), the level of eGFP is proportionally decreased when the number of repeats is increased suggesting that the repeated element loses its anti-CPE activity upon multimerization. …”

Computational evidence for an early, amplified systemic inflammation program in polytrauma patients with severe extremity injuries by Khalid Almahmoud (492319)

“…The higher severity cohort had statistically significant elevated lactate, base deficit, and creatine phosphokinase on first blood draw, along with significant changes in multiple circulating inflammatory mediators. DyNA pointed to a sustained role for type 17 immunity in both sub-cohorts, along with IFN-γ in the severe extremity injury group. …”

Knockdown of SURFIN4.1 leads to the increase of steady state levels of <i>surf</i>4 transcripts and perhaps others. by Tatiane Macedo-Silva (4351135)

“…Note that while <i>surf4</i> showed more transcript at 96 h without Shield-1 (as shown in <b>B</b>, coinciding with decreased SURF4.1 protein, compare with <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0183129#pone.0183129.g003" target="_blank">Fig 3</a>), the quantity of the <i>surf9</i> transcript also reproducibly increased.…”

The tempo and mode of the taxonomic correction process: How taxonomists have corrected and recorrected North American bird species over the last 127 years by Gaurav Vaidya (5122022)

“…<div><p>While studies of taxonomy usually focus on species description, there is also a taxonomic correction process that retests and updates existing species circumscriptions on the basis of new evidence. …”

Image_1_Clinically important change on the Unified Dyskinesia Rating Scale among patients with Parkinson's disease experiencing dyskinesia.jpg by Rajesh Pahwa (6816655)

“…UDysRS reduction of ≥9 points corresponded to decreased ON time with troublesome dyskinesia of ≥0.5 h per patient diaries, and UDysRS reduction of ≥10 points corresponded to at least minimal improvement on the CGI-C.…”

Mutation of acetylated lysine residues results in mislocalization of NDPK-D. by Yuki Fujita (330873)

“…Acetylation levels were determined as described in (A). Replacement of lysine residues with arginine decreased acetylation levels. n = 3. …”

Stimulus-locked ERPs and scalp topographies for both experimental conditions. by Marijn van Vliet (587742)

“…Note that the y-axes have different scales and each scalp topography uses its own normalized scale. <b>A</b>: Stimulus-locked ERP of the speeded condition; trials sorted by decreasing AS. …”

Structure−Reactivity Studies in Copper(II)-Catalyzed Phosphodiester Hydrolysis by Eric L. Hegg (118846)

“…Larger macrocycles also result in the copper ion being pulled closer to the plane defined by the three ligand nitrogens, which in turn results in an increase in the sum of the three N−Cu−N angles from 249° to 257° to 278° along with a concomitant decrease in the X−Cu−X angle. Significantly, the rate constant for the hydrolysis of BNPP by Cu([9−11]aneN₃)X₂ increases by nearly an order of magnitude as the ligand size increases from a nine-membered to an 11-membered ring. …”

TF function predicted from regulatory parameters <i>α</i> and <i>β</i>. by Md Zulfikar Ali (11965544)

“…Black contours mark FC_max = 1 and subsequent contours represent 100–fold increase or decrease in FC_max. The observed regulation from a TF depends on promoter strength. …”

Fig 1 - by Simone Bach (9339740)

“…<p>(<b>A</b>) Schematic presentation of the EBOV genome. …”

Modulation of Notch signaling affects axon outgrowth. by Ming Shi (78991)

“…(B–B'') Mis-expression of NICD results in a drastic decrease in the number of commissural axons crossing the midline. …”

Spatial Variation in Nutrient and Water Color Effects on Lake Chlorophyll at Macroscales by C. Emi Fergus (3220110)

“…Water color was not related to CHL for the majority of lakes, but there were some locations where water color had a positive effect such that a unit increase in water color resulted in a 2 μg/L increase in CHL and other locations where it had a negative effect such that a unit increase in water color resulted in a 2 μg/L decrease in CHL. …”

The life cycle of intensifiers, with empirical examples. by Madison S. Krieger (4487053)

“…Once a word has “used up” its hyperbolic value, it decreases in usage and is supplanted either by a new bleached word or, frequently, by an older hyperbolic term whose loss of value has been forgotten by the current generation (a process called “recycling”, shown in blue). …”

Randomised Pharmacokinetic Trial of Rifabutin with Lopinavir/Ritonavir-Antiretroviral Therapy in Patients with HIV-Associated Tuberculosis in Vietnam by Nguyen Thi Ngoc Lan (269014)

“…Rifabutin 150 mg daily with lopinavir/ritonavir was associated with a 32% mean increase in rifabutin average steady state concentration compared with rifabutin 300 mg alone. …”

Data_Sheet_1_Excessive Daytime Sleepiness in Obstructive Sleep Apnea Patients Treated With Continuous Positive Airway Pressure: Data From the European Sleep Apnea Database.docx by Maria R. Bonsignore (3193020)

“…In conclusion, residual EDS in CPAP-treated OSA occurred in approximately one in four patients at follow-up; its prevalence was highest (40%) in the first 3 months of treatment and subsequently decreased. The finding of residual EDS in a significant percentage of optimally treated OSA patients suggests that wake-promoting agents may be useful, but their indication should be evaluated after at least 3 months of treatment.…”

Long-term changes in the density and composition of profundal macrobenthos in Lake Biwa from 1966 to 2000 by Tetsuya Narita (19330967)

“…To examine the effects of these environmental changes on dominant macrobenthos species in Lake Biwa, the density and composition of these organisms were determined monthly from 1966 to 2000 at an offshore station in the lake and analyzed in terms of various physicochemical factors. Annual mean bottom temperatures at the site generally remained stable (6.1–8.0 °C) until 1985, increased from 1985 (6.5 °C) to 1990 (8.3 °C), and remained high thereafter (7.4–8.3 °C). …”

Rosiglitazone and SB203580 suppressed the mRNA expression of α-SMA, Col I, and CTGF. by Yong-Heng Luo (619449)

“…Next, the cells were incubated with 5 ng/mL TGF-β1 in the presence of rosiglitazone or SB203580 for 12 h (for CTGF mRNA analysis) or 24 h (for α-SMA and Col I mRNA analysis). …”

Gene expression by biophysical subset. by Tom Bongiorno (4922701)

“…<p>An enrichment of pluripotent cells in the soft outlet was indicated by decreased <i>Nanog</i> in the stiff outlet and increased <i>Pou5f1</i> in the soft outlet, relative to the middle outlet. …”

Nutritional status of children residing in an area of social vulnerability: longitudinal study by Dixis Figueroa Pedraza (4646089)

“…<p></p><p>ABSTRACT The aim of this article was to analyze the variation of anthropometric parameters over the course of two years of children under five years of age living in a vulnerability area, according to demographic and health profile. …”