Table_2_Gene Co-expression Network Reveals Potential New Genes Related to Sugarcane Bagasse Degradation in Trichoderma reesei RUT-30.XLSX by Gustavo Pagotto Borin (751443)

“…Our results demonstrate a vast range of new promising targets that merit additional studies to improve the cellulolytic potential of T. reesei strains and to decrease the production costs of 2G ethanol.…”

CD36 and Fyn Kinase Mediate Malaria-Induced Lung Endothelial Barrier Dysfunction in Mice Infected with <i>Plasmodium berghei</i> by Ifeanyi U. Anidi (446498)

“…To define the role that the scavenger receptor CD36 may play in mediating this response, C57BL/6J (WT) and CD36−/− mice were infected with <i>P. berghei</i> ANKA and monitored for changes in pulmonary endothelial barrier function employing an isolated perfused lung system. WT lungs demonstrated a >10-fold increase in two measures of paracellular fluid conductance and a decrease in the albumin reflection coefficient (σ_alb) compared to control lungs indicating a loss of barrier function. …”

Transcription of Biotic Stress Associated Genes in White Clover (<i>Trifolium repens L</i>.) Differs in Response to Cyst and Root-Knot Nematode Infection by Afsana Islam (798416)

“…Invasion by the CRKN resulted in a significant decrease in transcript abundance of <i>Tr-KPI4</i> locally at both 4 days post-infection (dpi) and at 8 dpi, and an increase in transcription of <i>Tr-KPI1</i> systemically at 8 dpi. …”

DataSheet1_BCI, an inhibitor of the DUSP1 and DUSP6 dual specificity phosphatases, enhances P2X7 receptor expression in neuroblastoma cells.docx by María Benito-León (544046)

“…BCI enhanced dual specificity phosphatase 1 expression, whereas it induced a decrease in the dual specificity phosphatase 6 transcripts, suggesting that BCI-dependent inhibition of dual specificity phosphatase 1 may be responsible for the increase in p38 and JNK phosphorylation. …”

Table_1_Long Non-coding RNAs Rian and Miat Mediate Myofibroblast Formation in Kidney Fibrosis.xlsx by Roel Bijkerk (4662769)

“…In order to identify pericyte long non-coding RNAs (lncRNAs) that could serve as a target to decrease myofibroblast formation and counteract the progression of kidney fibrosis we employed two models of experimental kidney injury, one focused on kidney fibrosis (unilateral ureteral obstruction; UUO), and one focused on acute kidney injury that yields kidney fibrosis in the longer term (unilateral ischemia-reperfusion injury; IRI). …”

Table_1_Luteolin Modulates Neural Stem Cells Fate Determination: In vitro Study on Human Neural Stem Cells, and in vivo Study on LPS-Induced Depression Mice Model.pdf by Mariem Achour (11630299)

“…We found that oral administration of luteolin (10 mg/Kg) for eight consecutive days could decrease the immobility time on tail suspension test, a mouse behavioral test measuring depression-like behavior, and attenuate LPS-induced inflammatory responses by significantly decreasing IL-6 production in mice brain-derived astrocytes and serum, and TNFα and corticosterone levels in serum. …”

Human cytomegalovirus UL23 inhibits transcription of interferon-γ stimulated genes and blocks antiviral interferon-γ responses by interacting with human N-myc interactor protein by Linyuan Feng (4804452)

“…Thus, UL23 appears to interact directly with Nmi and inhibit nuclear translocation of Nmi and its associated protein STAT1, leading to a decrease of IFN-γ induced responses and an increase of viral resistance to IFN-γ. …”

Data_Sheet_1_Association Between Response to Nivolumab Treatment and Peripheral Blood Lymphocyte Subsets in Patients With Non-small Cell Lung Cancer.docx by Selene Ottonello (8416638)

“…<p>Immune checkpoint blockade represents a major breakthrough in advanced non-small cell lung cancer (NSCLC) therapy. …”

DataSheet_1_Exploring preferences of different modes of administration of hypomethylating agent treatments among patients with acute myeloid leukemia.pdf by Audrey Delmas (6237905)

“…Hypomethylating Agents (HMAs) intravenously (IV) or subcutaneously (SC) in a clinical setting are typically offered as an alternative. …”

Actionable Gene Expression-Based Patient Stratification for Molecular Targeted Therapy in Hepatocellular Carcinoma by Jung-Hee Kwon (421854)

“…Up-regulation of EGFR was observed at early stage and tended to gradually decrease toward late stages (BCLC stage A: 41.9%; B: 30.8%; C: 17.6%). …”

Image_1_Tumor-Derived Exosomes Enriched by miRNA-124 Promote Anti-tumor Immune Response in CT-26 Tumor-Bearing Mice.TIF by Ramazan Rezaei (8192640)

“…Significant tumor growth inhibition and increased median survival time was achieved in tumor-bearing mice treated with TEXomiR. A significant decrease in CD4/CD8 and Treg/CD8 ratio in tumor tissue was demonstrated. …”

PPAR-γ agonist inhibited TF expression in ECs, monocytes and SMCs. by Jun-Bean Park (195391)

“…<p>(<b>A</b>) The PPAR-γ agonist suppressed TNF-α-induced TF expression in HUVECs in a concentration-dependent manner. …”

Elephant seal dive behaviour responds consistently to changes in foraging success regardless of sex or ocean habitat by David Green (10157417)

“…We found that as foraging success increased, seals increased transit (ascent, descent) rates and decreased relative dive durations for a given depth, with no response in surface recovery. …”

Trial design. by Llum Páez (22553360)

“…<div><p>Canine leishmaniasis is a vectorial zoonotic disease caused by the obligate intracellular trypanosomatid parasite <i>Leishmania infantum</i>. …”

Inhibition of Hsp70 isoforms prevented Hsc70 chaperone recruitment to KSHV RTCs and RTC formation. by Belinda Baquero-Pérez (706834)

“…Equal amounts of total protein from each fraction were analysed by Western blotting. A slight increase in cytoplasmic Hsc70 which correlated with a small decrease in nuclear Hsc70 was detected in inhibitor-treated cells. …”

Schedule of the trial. by Llum Páez (22553360)

“…<div><p>Canine leishmaniasis is a vectorial zoonotic disease caused by the obligate intracellular trypanosomatid parasite <i>Leishmania infantum</i>. …”

Clinical symptoms scoring system. by Llum Páez (22553360)

“…<div><p>Canine leishmaniasis is a vectorial zoonotic disease caused by the obligate intracellular trypanosomatid parasite <i>Leishmania infantum</i>. …”

phospho-Ser65 triggers cleft widening in the N-terminal region. by Thomas R. Caulfield (655752)

“…An increase in SASA over time is also observed for the substitutions S65D and S65E as well as for S65A after an initial decrease. <b>G</b>) Shown are numbers of H₂O molecules within the cavity surrounding Ser65 during MDS. …”

3D motility of the Δ<i>phil1</i> parasites. by Jacqueline M. Leung (120235)

“…The Δ<i>phil1</i> parasites also exhibited significantly decreased mean velocity compared to the RH parasites (<b>E</b>) and significantly reduced maximum velocity compared to both RH and Comp parasites (<b>F</b>) (paired t-test, significance indicated by asterisks). …”

Loss of IRS2 promotes stromal activation and inhibits HSC reversion. by Fátima Manzano-Núñez (6273674)

“…(A) RT-qPCR analysis of LX-2 cells and primary hHSC cultures treated with vehicle (cont) or MitoC for 72 h prior to harvesting showing decreased <i>COL1A1</i> expression together with concomitant increase in HSC reversion marker HSPA1B (<i>n</i> = 3). …”