Data_Sheet_9_Resolvin E1-ChemR23 Axis Regulates the Hepatic Metabolic and Inflammatory Transcriptional Landscape in Obesity at the Whole Genome and Exon Level.DOCX by Abrar E. Al-Shaer (6580940)

“…Notably, obese WT mice relative to lean controls showed a robust decrease in pathways related to the biosynthesis of unsaturated fatty acids. …”

Table 1_Blastocystis infection in Tibetan antelopes (Pantholops hodgsonii) alters gut microbiota composition and function.xlsx by Jian Liu (33711)

“…Functional profiling showed a decrease in metabolic diversity, with 18 CAZy families detected in the healthy group but only 2 in the infected group. …”

Data_Sheet_1_National situation, trends, and predictions of disease burden of atopic dermatitis in Chinese children and adolescents.docx by Yang Guo (399435)

“…The prediction analyses found a slight decreasing trend for cases of these measures and a slight increasing trend for rates of these measures in the <5 years group in the next 10 years; the 5–9 years group was predicted to increase slightly in rates of the three measures.…”

Table_1_The association between sugar-sweetened beverages and milk intake with emotional and behavioral problems in children with autism spectrum disorder.pdf by Si Tan (547511)

“…The frequency of SSBs and milk intake was assessed by a self-designed questionnaire. Emotional and behavioral problems were assessed by Strength and Difficulties Questionnaire (SDQ). …”

Image2_TCR-Induced Tyrosine Phosphorylation at Tyr270 of SUMO Protease SENP1 by Lck Modulates SENP1 Enzyme Activity and Specificity.JPEG by Yun-Yi Li (12031955)

“…Through in vivo isopeptidase activity analysis by rescue expression of SENP1 and its Y270 mutants in a SENP1 CRISPR knockout T cell line, we found that SENP1 Y270F downregulated its isopeptidase activity towards both SUMO1 and SUMO2/3 conjugation by reducing SENP1 binding with sumoylated targets. …”

Enteral fluid therapy administered in continuous flow by naso-ruminal route using three maintenance electrolyte solutions: effects on physiological biomarkers and the hemogram of b... by Pedro Ancelmo Nunes Ermita (5611484)

“…All solutions resulted in a significant decrease in erythrocyte concentration, hemoglobin concentration, and hematocrit, without affecting the leukogram. …”

Image2_Magnolol Attenuates Right Ventricular Hypertrophy and Fibrosis in Hypoxia-Induced Pulmonary Arterial Hypertensive Rats Through Inhibition of the JAK2/STAT3 Signaling Pathway... by Minyi Fu (11605909)

“…Magnolol (6, 6′, 7, 12-tetramethoxy-2,2′-dimethyl-1-β-berbaman, C18H18O2) is a compound isolated from Magnolia Officinalis. …”

Image_6_Porphyromonas gingivalis-Induced NLRP3 Inflammasome Activation and Its Downstream Interleukin-1β Release Depend on Caspase-4.TIF by Pei-Hui Ding (3909724)

“…In addition, silencing of either CASP4 or CASP1 can lead to a concurrent or reciprocal decrease in the expression of the other. …”

Detailed Analysis of Sequence Changes Occurring during <em>vlsE</em> Antigenic Variation in the Mouse Model of <em>Borrelia burgdorferi</em> Infection by Loïc Coutte (124900)

“…The <em>vls</em> antigenic variation system, which expresses the surface-exposed lipoprotein VlsE, plays a major role in <em>B. burgdorferi</em> immune evasion. …”

Data_Sheet_3_Resolvin E1-ChemR23 Axis Regulates the Hepatic Metabolic and Inflammatory Transcriptional Landscape in Obesity at the Whole Genome and Exon Level.XLSX by Abrar E. Al-Shaer (6580940)

“…Notably, obese WT mice relative to lean controls showed a robust decrease in pathways related to the biosynthesis of unsaturated fatty acids. …”

Bacteria Contribute to Sediment Nutrient Release and Reflect Progressed Eutrophication-Driven Hypoxia in an Organic-Rich Continental Sea by Hanna Sinkko (215613)

“…<div><p>In the sedimental organic matter of eutrophic continental seas, such as the largest dead zone in the world, the Baltic Sea, bacteria may directly participate in nutrient release by mineralizing organic matter or indirectly by altering the sediment’s ability to retain nutrients. Here, we present a case study of a hypoxic sea, which receives riverine nutrient loading and in which microbe-mediated vicious cycles of nutrients prevail. …”

The result compared with other existing methods. by Ke Yan (331581)

“…On the other hand, taking English writing teaching as an example, the proposed method is further verified by designing a comparative experiment in groups. The results show that: (1) From the experimental data of word sense disambiguation, the accuracy of the SMOSS-LSTM model proposed in this paper is the lowest when the context range is "3+3", then it rises in turn at "5+5" and "7+7", reaches the highest at "7+7", and then begins to decrease at "10+10"; (2) Compared with the control group, the accuracy of syntactic analysis in the experimental group reached 89.5%, while that in the control group was only 73.2%. (3) In the aspect of English text error detection, the detection accuracy of the proposed model in the experimental group is as high as 94.8%, which is significantly better than the traditional SMOSS-based text error detection method, and its accuracy is only 68.3%. (4) Compared with other existing researches, although it is slightly inferior to Bidirectional Encoder Representations from Transformers (BERT) in word sense disambiguation, this proposed model performs well in syntactic analysis and English text error detection, and its comprehensive performance is excellent. …”

Image_2_The association between sugar-sweetened beverages and milk intake with emotional and behavioral problems in children with autism spectrum disorder.tiff by Si Tan (547511)

“…The frequency of SSBs and milk intake was assessed by a self-designed questionnaire. Emotional and behavioral problems were assessed by Strength and Difficulties Questionnaire (SDQ). …”

IL-12p40 Deficiency Leads to Uncontrolled <em>Trypanosoma cruzi</em> Dissemination in the Spinal Cord Resulting in Neuronal Death and Motor Dysfunction by André Luis Bombeiro (121574)

“…Forelimb paralysis in infected IL-12p40KO mice was associated with 60% (p<0.05) decrease in spinal cord neuronal density, glutamate accumulation (153%, p<0.05) and strong demyelization in lesion areas, mostly in those showing heavy protein nitrosylation, all denoting a neurotoxic degenerative profile. …”

Data_Sheet_3_Differential effects on TDP-43, piezo-2, tight-junction proteins in various brain regions following repetitive low-intensity blast overpressure.CSV by Lanier Heyburn (7055039)

“…</p>Methods<p>In this study, using a rodent model of relBOP and western blotting for protein expression we showed the differential expression of various neuropathological proteins like TDP-43, tight junction proteins (claudin-5, occludin, and glial fibrillary acidic protein (GFAP)) and a mechanosensitive protein (piezo-2) in different regions of the brain at different intensities and frequency of blast.…”

Data Sheet 1_Therapeutic plasma exchange accelerates immune cell recovery in severe COVID-19.pdf by Aurelie Guironnet-Paquet (15407171)

“…</p>Methods<p>In this study, we set up a prospective, randomised clinical trial (ClinicalTrials.gov ID: NCT04751643) and performed therapeutic plasma exchange (TPE) in severe COVID-19 patients in order to decrease excess cytokines and auto-antibodies and to assess whether adding TPE to the standard treatment (ST, including corticosteroids plus high-flow rate oxygen) could help restore immune parameters and limit the progression of acute respiratory distress syndrome (ARDS).…”

Table_2_Early Everolimus Initiation Fails to Counteract the Cytotoxic Response Mediated by CD8+ T and NK Cells in Heart Transplant Patients.DOCX by Beatriz Díaz-Molina (5791361)

“…Our results imply that only early EVL conversion induces key changes in the post-transplant immune response, preserving an efficient anti-viral response, but simultaneously showing a limited ability to counteract the cytotoxic response to the allograft.…”

Table_1_Sex hormones influence the intestinal microbiota composition in mice.DOCX by Yi Wu (197719)

“…The abundance of Parasutterella is positively and negatively correlated with estradiol and testosterone (T), respectively, which may be related to the differences in the metabolism of bile acid and glucose. A decrease in the abundance of Turicibacter is closely related to autism. …”

Progress toward implementing the Swiss Hepatitis Strategy: Is HCV elimination possible by 2030? by Beat Müllhaupt (416436)

“…<div><p>Catalyzed by the concerns over the growing public health and economic burden of Hepatitis C virus (HCV) in Switzerland, a diverse group of experts and patient representatives came together in 2014 to develop the Swiss Hepatitis Strategy, setting targets for the elimination of viral hepatitis in Switzerland by 2030. …”

Phenotype data of the meta-analysis cohorts. by Anu Pasanen (6836672)

“…<div><p>Background</p><p>Preterm birth (<37 weeks of gestation) is a major cause of neonatal death and morbidity. …”