Figure S5_1 from Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma by Joseph J. Caumanns (15010014)

“…<p>Supplementary Figure 5 | Clustering (n=106) and survival analysis (n=70) on kinome mutations and CNA. (A) Disease-specific survival of patients (n=70) grouped on ARID1A status, (B) PIK3CA status and (C) ARID1A + PIK3CA status. …”

Table_5_Gene Co-expression Network Reveals Potential New Genes Related to Sugarcane Bagasse Degradation in Trichoderma reesei RUT-30.XLSX by Gustavo Pagotto Borin (751443)

“…Our results demonstrate a vast range of new promising targets that merit additional studies to improve the cellulolytic potential of T. reesei strains and to decrease the production costs of 2G ethanol.…”

Testing phase. by Daniel M. Mwanga (20037196)

“…Based on a previously used manual tool, in June 2022, we developed a digital online data capture and reporting tool using the open-source Kobo toolbox. …”

Data_Sheet_1_Staphylococcus aureus Alpha-Toxin Limits Type 1 While Fostering Type 3 Immune Responses.docx by Agnes Bonifacius (9127764)

“…To develop such novel treatment approaches, a better understanding of the bacterial virulence and immune evasion mechanisms and their potential effects on immune-based therapies is essential. …”

Table_1_Schwann cell-derived exosomes ameliorate peripheral neuropathy induced by ablation of dicer in Schwann cells.DOCX by Lei Wang (6656)

“…</p>Results<p>Compared to the WT mice, PLP-cKO mice exhibited a significant decrease in motor and sensory conduction velocities, thermal sensitivity, and motor coordination. …”

Table_2_Prospective Study Reveals Host Microbial Determinants of Clinical Response to Fecal Microbiota Transplant Therapy in Type 2 Diabetes Patients.xlsx by Dafa Ding (6548732)

“…</p>Results<p>We found that the GM of T2DM patients was reconstituted by FMT. We observed a statistically significant decrease in HbA1c% (from 7.565 ± 0.148 to 7.190 ± 0.210, p<0.01), blood glucose (from 8.483 ± 0.497 to 7.286 ± 0.454 mmol/L, p<0.01), and uric acid (from 309.4 ± 21.5 to 259.1 ± 15.8 µmol/L, p<0.01) while a significant increase in postprandial C-peptide (from 4.503 ± 0.600 to 5.471 ± 0.728 ng/ml, p<0.01) at 12 weeks after FMT. …”

Table2_Glycoproteomic Characterization of FUT8 Knock-Out CHO Cells Reveals Roles of FUT8 in the Glycosylation.XLSX by Ganglong Yang (778465)

“…Meantime, a total of 51 glycosylation-related enzymes were also quantified in these two cell types and 16 of them were significantly altered in the FUT8KO cells, in which sialyltransferases and glucosyltransferases were sharply decreased. …”

Table_1_Extrapolating Antibiotic Sales to Number of Treated Animals: Treatments in Pigs and Calves in Switzerland, 2011–2015.DOCX by Rosa Stebler (7408247)

“…An analysis of treatment intensity at antimicrobial class level showed a decrease of 64% for colistin used in pigs, and of 7% for macrolides used in both pigs and calves. …”

Data_Sheet_1_IgG Antibody Responses to the Aedes albopictus 34k2 Salivary Protein as Novel Candidate Marker of Human Exposure to the Tiger Mosquito.PDF by Sara Buezo Montero (7507955)

“…Finally, determination of anti-al34k2 IgG1 and IgG4 levels indicated a large predominance of IgG1 antibodies. Overall, this study provides a convincing indication that antibody responses to al34k2 may be regarded as a reliable candidate marker to detect temporal and/or spatial variation of human exposure to Ae. albopictus; a serological tool of this kind may prove useful both for epidemiological studies and to estimate the effectiveness of anti-vectorial measures.…”

Image_2_Corticosteroid-depending effects on peripheral immune cell subsets vary according to disease modifying strategies in multiple sclerosis.tiff by Lena Höpner (18815950)

“…</p>Methods<p>We conducted immunophenotyping using flow cytometry on peripheral blood mononuclear cells of pwMS who received IVMP treatment during a relapse. We compared the impact of an IVMP treatment on a broad variety of immune cell subsets within three groups: twelve patients who were treatment-naïve to disease modifying therapies (wDMT) to ten patients on platform therapies (PT) and eighteen patients on fingolimod therapy (FTY).…”

Image_1_Warming and CO2 Enhance Arctic Heterotrophic Microbial Activity.TIF by Dolors Vaqué (683567)

“…Results showed that chlorophyll a concentration decreased at increasing temperatures, while BP significantly increased with pCO₂ at 6 and 10°C. …”

Table_1_Genes related to osmoregulation and antioxidation play important roles in the response of Trollius chinensis seedlings to saline-alkali stress.docx by Rongmiao Hou (14507159)

“…<p>Saline-alkali stress is one of the main abiotic stress factors affecting plant growth and development. Trollius chinensis is a perennial herbal medicinal plant with high values for garden application. …”

Table_2_Adult Female Sleep During Hypoxic Bed Rest.docx by Jeroen Van Cutsem (3328725)

“…Purpose<p>Hypobaric hypoxic habitats are currently being touted as a potential solution to minimise decompression procedures in preparation for extra vehicular activities during future space missions. …”

Data_Sheet_1_Health-related heterogeneity in brain aging and associations with longitudinal change in cognitive function.docx by Jo Wrigglesworth (6563171)

“…Among resilient brain agers, class 1 was associated with a decrease in cognition, and class 2 with an increase over 5 years, though was a small effect that was equivalent to a 0.04 standard deviation difference per year. …”

Data_Sheet_1_Identification of Quantitative Trait Loci Associated With Iron Deficiency Tolerance in Maize.docx by Jianqin Xu (833917)

“…Compared with N1, N2 resulted in a 70.0% decrease of the root Fe concentration for Wu312 in the −Fe treatment, N2 treatment reduced the root Fe concentration of Ye478 by 55.8% in the −Fe treatment. …”

Data_Sheet_1_Genome-Wide Characterization of Ascorbate Peroxidase Gene Family in Peanut (Arachis hypogea L.) Revealed Their Crucial Role in Growth and Multiple Stress Tolerance.ZIP by Ali Raza (3558965)

“…<p>Ascorbate peroxidase (APX), an important antioxidant enzyme, plays a significant role in ROS scavenging by catalyzing the decrease of hydrogen peroxide under various environmental stresses. …”

Data_Sheet_1_Sepsis Disrupts Mitochondrial Function and Diaphragm Morphology.docx by Thamires Siqueira Oliveira (11398496)

“…Total and healthy mitochondria were reduced by 30% in septic mice, which may be associated with a 50% decrease in Ppargc1a (encoding PGC1a) and Opa1 (mitochondria fusion marker) expressions in the septic diaphragm. …”

Data_Sheet_1_Duration of the effectiveness of nicotine electronic cigarettes on smoking cessation and reduction: Systematic review and meta-analysis.docx by Paul Vanderkam (13196394)

“…The primary endpoint was smoking cessation at the end of the intervention and follow-up periods confirmed by a reduction in expired CO < 10 ppm. The reduction was defined as at least 50% of the initial consumption or by a decrease of daily mean cigarette consumption at the end of the intervention and follow-up periods.…”

Table_2_Schwann cell-derived exosomes ameliorate peripheral neuropathy induced by ablation of dicer in Schwann cells.DOCX by Lei Wang (6656)

“…</p>Results<p>Compared to the WT mice, PLP-cKO mice exhibited a significant decrease in motor and sensory conduction velocities, thermal sensitivity, and motor coordination. …”

Image_1_P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3*Leiden Mice via Systemic Inhibition of Regulatory T Cells.JPEG by Alwin de Jong (4012250)

“…In atherosclerotic lesions, no differences were observed in macrophage differentiation or VSMC content, although a small increase in collagen was identified.</p><p>Conclusion: Our data show that PCAF deficiency resulted in a decrease in circulatory FoxP3⁺ regulatory T cells and ameliorated atherosclerotic lesions with no differences in systemic inflammation or macrophage differentiation in the atherosclerotic lesions. …”