Amagnetic ergometer (LODE, Netherlands) allowing a supine treadmill test during MRI (1.5 T). by Laurence Bal-Theoleyre (2839193)

An old medicine as a new drug to prevent mitochondrial complex I from producing oxygen radicals by Dominique Detaille (3768979)

“…<div><p>Findings</p><p>Here, we demonstrate that OP2113 (5-(4-Methoxyphenyl)-3H-1,2-dithiole-3-thione, CAS 532-11-6), synthesized and used as a drug since 1696, does not act as an unspecific antioxidant molecule (i.e., as a radical scavenger) but unexpectedly decreases mitochondrial reactive oxygen species (ROS/H₂O₂) production by acting as a specific inhibitor of ROS production at the I_Q site of complex I of the mitochondrial respiratory chain. …”

Impact of Compliance with a Care Bundle on Acute Kidney Injury Outcomes: A Prospective Observational Study by Nitin V. Kolhe (300674)

“…</p><p>Conclusions</p><p>Compliance with AKI CB was associated with a decrease in case-fatality and reduced progression to higher AKI stage. …”

A 9-month analysis of the changes in hemoglobin A1c (HbA1c) level following a three-month vitamin D supplementation in patients with either type 1 diabetes or type 2 diabetes. by Benjamin Udoka Nwosu (476930)

“…In T2D, there was a clinically significant decrease in HbA1c <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0099646#pone.0099646-Thomas1" target="_blank">[36]</a> in the first 3 months (during the period of vitamin D supplementation) from 8.5±2.9% at baseline through 7.7±2.5% at 3 mo, followed by a slow return to pretreatment values of 8.2±2.3% at 9 mo. …”

Fibrosis-related renal protein expression as assessed with Western blot. by Jeonghwan Lee (286889)

“…<p>(A) Expression of αSMA did not decrease after p38 MAPK inhibitor administration. …”

Data_Sheet_1_A Two-Time Point Analysis of Gut Microbiota in the General Population of Buenos Aires and Its Variation Due to Preventive and Compulsory Social Isolation During the CO... by Pablo Aguilera (4621549)

“…Although no strong change was observed in the core microbiota between the groups in this study, a significant decrease was observed during PCSI in the phylum Verrucomicrobia, which contributes to intestinal health and glucose homeostasis. …”

Expression of LvrAB requires at least one functional PerR homolog but the absence of LvrAB alone is not solely responsible for avirulence of the <i>perRA/B</i> double mutant. by André A. Grassmann (11141592)

Cellular mRNA expression of fibrosis-related markers after exposure to TGF-β in the presence of p38 MAPK inhibitor. by Jeonghwan Lee (286889)

“…<p>(A) COL1 expression was increased after exposure to TGF-β (2 ng/ml). …”

IMM correlates with hind limb muscle weight in SOD1^G93A mice as disease progresses. by Laura Pasetto (4906006)

“…<p>(A) IMM was evaluated in Ntg and longitudinally in SOD1^G93A mice at 12, 14, 17 and 20 weeks of age (n = 5 for each group). …”

Fibrosis-related mRNA expression as assessed with RT-PCR. by Jeonghwan Lee (286889)

“…<p>(A) Expression of αSMA was decreased in the 10 mg/kg/day p38 MAPK inhibitor group. …”

DataSheet_1_Growth, biofiltration and photosynthetic performance of Ulva spp. cultivated in fishpond effluents: An outdoor study.docx by Thaís Fávero Massocato (13581751)

“…Additionally, after 5 days of cultivation under 50% fish effluent both Ulva species were able to remove more than 85% of the nitrate. Although a decrease in uptake efficiency was observed in cultures with 100% fish effluent, at the end of the experiment more than 440 µmol L^-1 of nitrate was removed, considering all treatment conditions. …”

Further optimisation and <i>in vitro</i> characterization of influenza A reporter viruses. by Monique I. Spronken (779529)

“…<p>(A) A schematic representation of adjustments to the 2UP_PA_eGFP_dPR construct. …”

The folding stability for folding with and without interfacial binding shown in (A) heat capacity curves and (B) free energy landscapes for Lambda Cro repressor (red) and Lambda re... by Xiakun Chu (151393)

In native cartilage, lubricin bound to the surface facilitates HA aggregation near the surface (A). Lubricin likely entraps HA through entanglements, causing a local increase in viscosity near the tissue surface (A, inset). When lubricin is removed from the surface, HA does not aggregate (B) and surface viscosity is likely similar to the bulk (B, inset). Boundary lubrication by lubricin shifts the boundary regime down and increased viscosity near the surface shifts the elastoviscous transition such that the low friction regime occurs at lower sliding speeds consistent with viscous boundary lubrication (C). These phenomena of lubricin and HA replicate the lubrication by synovial fluid which transition to low friction at low speeds. By treating synovial fluid with hyaluronidase, friction is shifted back towards the boundary mode plateau as the fluid viscosity decreases, and trypsin treatment disrupts the synergy between lubricin and HA by digesting lubricin (n = 4; data points represent by Edward D. Bonnevie (830252)

“…By treating synovial fluid with hyaluronidase, friction is shifted back towards the boundary mode plateau as the fluid viscosity decreases, and trypsin treatment disrupts the synergy between lubricin and HA by digesting lubricin (n = 4; data points represent mean±SEM).…”

Correlation between AOI dwell time and WSD. by Nak Won Rim (10776698)

Socio-demographic factor for two cohorts aged 18-24 and 32-38 in 2016 in Gauteng. by Edmore Marinda (286299)

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Variables making up each of the seven dimensions of the QoL Index. by Edmore Marinda (286299)

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Changes in QOL scores among two cohorts aged 18-24 years and 32-38-year-olds in 2016 over four rounds of QOL surveys 2016 - 2024 in Gauteng, South Africa. by Edmore Marinda (286299)

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Sample Size for QoL tracking study for young people aged 18 to 24 in Gauteng, 2016 - 2024. by Edmore Marinda (286299)

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Quality of Life changes between 2016 and 2024 for two age cohorts staying in Gauteng. by Edmore Marinda (286299)

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