Image_2_Pharmacological Disruption of Phosphorylated Eukaryotic Initiation Factor-2α/Activating Transcription Factor 4/Indian Hedgehog Protects Intervertebral Disc Degeneration via... by Junping Bao (10931142)

“…On the contrary, further activating p-eIF2α aggravated the NP cell degeneration, with amplification of ATF4/Ihh and a higher level of ROS and apoptosis. Additionally, applying cyclopamine (CPE) to suppress Ihh was efficient to prevent NP cell apoptosis but did not decrease the ROS level. …”

image2_Significant Regional Differences in Lung Cancer Incidence in Hungary: Epidemiological Study Between 2011 and 2016.jpg by Gabriella Gálffy (177759)

“…</p><p>Results: The highest incidence rate in males was recorded in Northern Hungary (146.8/100,000 person-years [PY]), while the lowest rate was found in Western Transdanubia (94.7/100,000 PY in 2011). All rates showed a declining trend between 2011 and 2016, with the largest decrease in the Northern Great Plain (−20.0%; p = 0.008). …”

Table_3_T cell receptor β repertoires in patients with COVID-19 reveal disease severity signatures.xlsx by Jing Xu (15337)

“…</p>Results<p>We observed a decrease in the diversity of TCR clonotypes in COVID-19 patients compared to healthy controls. …”

Fer expression in zebrafish embryos and Fer MO induced splicing defects. by Jeroen Paardekooper Overman (552100)

“…RT-PCR showing <i>Fer</i> product in Nacre control MO and Fer e9i9 MO injected embryos with a decrease in size of the product in e9i9 MO injected embryos. …”

Data_Sheet_1.xls by Qianqian Shi (158387)

“…<p>Meloidogyne incognita is highly specialized parasite that interacts with host plants using a range of strategies. The effectors are synthesized in the esophageal glands and secreted into plant cells through a needle-like stylet during parasitism. …”

Sodium chloride induces vesicle formation of microglia/macrophages. by Antje Schmidt-Pogoda (6160244)

“…<b>(C)</b> Arginase-1-stainings illustrated a significant decrease of Arginase-1⁺-anti-inflammatory cells following high-salt diet (p<0.05, t-test, n = 15 per group). …”

Inotodiol inhibits HCC cells migration. by Yushuang Xing (20636685)

“…In addition, inotodiol showed to induce apoptosis, characterized by an increase in Bax expression, a decrease in Bcl-2, Bcl-XL and MCL1 expression, the initiation of cleaved PARP1 and cleaved caspase 3, and inhibition of the MAPK/ERK pathway. …”

Subcellular accumulation of Crb during tracheal development. by Ivette Olivares-Castiñeira (4224871)

“…<p>(A-E) Lateral views of wild type embryos at indicated stages stained for E-Cadh (green, white) and Crb (red, white), showing 1–2 tracheal metameres. …”

Image_5_T cell receptor β repertoires in patients with COVID-19 reveal disease severity signatures.pdf by Jing Xu (15337)

“…</p>Results<p>We observed a decrease in the diversity of TCR clonotypes in COVID-19 patients compared to healthy controls. …”

Laparoscopic Cholecystectomy for Gallbladder Calculosis in Fibromyalgia Patients: Impact on Musculoskeletal Pain, Somatic Hyperalgesia and Central Sensitization by Raffaele Costantini (819106)

“…Over the same 12-month period: in non-fibromyalgia patients undergoing cholecystectomy thresholds did not change; in all other fibromyalgia groups not undergoing cholecystectomy fibromyalgia pain and thresholds remained stable, except in fibromyalgia+symptomatic calculosis at 12months when pain significantly increased and muscle thresholds significantly decreased (p<0.05-p<0.0001). The results of the study show that biliary colics from gallbladder calculosis represent an exacerbating factor for fibromyalgia symptoms and that laparoscopic cholecystectomy produces only a transitory worsening of these symptoms, largely compensated by the long-term improvement/desensitization due to gallbladder removal. …”

Table1_Inflammatory priming with IL-1β promotes the immunomodulatory behavior of adipose derived stem cells.DOCX by Alessandra Colombini (285561)

“…Functional tests on immune cells showed that primed and non-primed ASCs induced a decrease in the CD3⁺ T lymphocytes survival rate and an anti-inflammatory macrophage polarization. …”

Table_1_Impaired Cytotoxic Response in PBMCs From Patients With COVID-19 Admitted to the ICU: Biomarkers to Predict Disease Severity.docx by Lorena Vigón (7325558)

“…<p>Infection by novel coronavirus SARS-CoV-2 causes different presentations of COVID-19 and some patients may progress to a critical, fatal form of the disease that requires their admission to ICU and invasive mechanical ventilation. …”

Steric and Electronic Influences of Buchwald-Type Alkyl-JohnPhos Ligands by Alexander J. Kendall (2261815)

“…The π-acidity and σ-donating properties of the R-JohnPhos ligands were quantified using a Cotton–Kraihanzel analysis of the Cr⁰(CO)₅(R-JohnPhos) complexes. …”

Table6_Revealing the Mechanism of Huazhi Rougan Granule in the Treatment of Nonalcoholic Fatty Liver Through Intestinal Flora Based on 16S rRNA, Metagenomic Sequencing and Network... by Yingying Liu (360782)

“…Analysis of intestinal flora showed that HRG changed the composition of intestinal flora, which was characterized by a decrease in the Firmicutes/Bacteroidetes ratio. …”

DataSheet_1_Colchicine Impacts Leukocyte Trafficking in Atherosclerosis and Reduces Vascular Inflammation.docx by Ulrike Meyer-Lindemann (12993186)

“…Colchicine, a microtubule inhibitor with anti-inflammatory properties, reduced cardiovascular events in patients with recent acute coronary syndrome and chronic coronary disease. …”

DataSheet_1_Understanding the role of membrane cholesterol upon Epstein Barr virus infection in astroglial cells.docx by Annu Rani (11223925)

“…Downstream molecules like STAT3 and RIP, exhibited a decrease in protein levels temporally upon exposure to MβCD while NF-kB levels were found to be increased. …”

Data_Sheet_2_The Food Additive β-Caryophyllene Exerts Its Neuroprotective Effects Through the JAK2-STAT3-BACE1 Pathway.PDF by Yujia Zhang (757462)

“…The cell morphology altered dramatically 72 h after transfection, becoming rounder, with a decrease in cell number. BCP exhibited the potential to dramatically increase PC-12 cell viability while protecting cell morphology. …”

Data Sheet 1_β-receptor blocker enhances anti-tumor immunity via inhibiting lactate-induced norepinephrine metabolism of macrophages during malignant pleural effusion.docx by Ru Zhang (431993)

“…In clinical practice, we observed that patients with malignant pleural effusion (MPE) and concurrent heart disease exhibited a decrease in MPE volumes following treatment with β-receptor blockers for heart disease. …”

Data_Sheet_3_Mapping the Establishment and Invasiveness Potential of Rainbow Trout (Oncorhynchus mykiss) in Turkey: With Special Emphasis on the Conservation of Native Salmonids.XL... by Baran Yoğurtçuoğlu (10019369)

“…We explored this potential through a combination of Maxent habitat suitability model and the Aquatic Species Invasiveness Screening Kit (AS-ISK) on the river basin scale by generating an overall risk score (ORS). …”

Data_Sheet_1_Association of Serum miR-186-5p With the Prognosis of Acute Coronary Syndrome Patients After Percutaneous Coronary Intervention.zip by Zhuoling Li (6800984)

“…Serum miR-186-5p levels in rats following LAD ligation were increased, and there was a decrease in myocardial miR-186-5p levels. Kyoto encyclopedia of genes and genomes (KEGG) analysis was performed to predict the related pathways of target genes of miR-186-5p, which suggested that miR-186-5p might be involved in ACS by regulating the inflammatory status and D-glucose metabolism. …”