Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”

The fold change and P value distribution of antibiotic resistance genes (ARGs) in B (composted pig manure) vs A (fresh pig manure). by Shuai Huang (60512)

Mean (Standard Deviation) at baseline and follow-up for fitness and peak KAM during gait. by Elora C. Brenneman (795723)

Sildenafil treatment during recovery does not affect hyperoxia-induced decreases in alveolar counts. by Marta Perez (526067)

SCS RNAi silencing results in growth phenotype and decreased ΔΨ_m in CMM_glc and CMM_gly medium. by Gergana Taleva (17131885)

Percentage decreases in scores of self-reported health, large muscle function, and mobility by chronic diseases per wave after disease incidence. by James Davis (2267599)

Clustering using the unweighted pair group method with arithmetic mean (UPGMA). by Nguyen Thi Hai (12700147)

Aging slows theta peak frequency (TPF) and decreases slow wave activity (SWA) at low frequencies (0.5–1.5 Hz). by Mathieu E. Wimmer (498169)

Fraction of time, the overall of the studied data trends durations follow a geometric distribution with parameter <i>p</i> = 0.5, and with any <i>p</i>, both cases for a significan... by Héctor Raúl Olivares-Sánchez (13014866)

Mean heart rate percentage difference (between CON and AI at each 15-second time span). by Jan Maleček (17396660)

Log2 fold change (FC) of the overlaps of lipid metabolites between the study groups and those significant metabolites that appear exclusively in a single group (unique) represented... by Laia Bertran (3685147)

Hepatic Expression of Detoxification Enzymes Is Decreased in Human Obstructive Cholestasis Due to Gallstone Biliary Obstruction by Jin Chai (183630)

“…</p><p>Conclusions</p><p>The levels of hepatic detoxification enzymes were significantly decreased in human obstructive cholestasis, and these decreases were positively associated with a marked reduction of FXR levels. …”

Resuscitation with AVP restores the mean arterial blood pressure. by Carrie A. Sims (4532332)

IRGM reduced expression efficiently decreases MeV, HCV and HIV-1 viral particles production. by Isabel Pombo Grégoire (193157)

Fig 5 - by Arjen Tilstra (6915227)

Nsp8 decreases antiviral immune and inflammatory responses and promotes SARS-CoV-2 infection. by Xiaolin Zhang (246784)

Up-regulation of <i>ATP5J</i> expression enhanced cell migration and decreased 5-Fu sensitivity in DLD1 cells. by Hongbo Zhu (14981)

<i>Syx5</i> suppression in <i>Drosophila</i> S2 cells decreases copper accumulation. by Melanie Norgate (234832)

Mean red and green fluorescence intensity data from three experiments of cyanobacteria. by Emma T. Brentjens (17295999)