R117H-7T and R117H-5T function (+/-) ivacaftor: estimates from <i>in vitro</i> measurements of channel function and transcript analysis. by Jessica E. Char (476386)

“…The 5T mutation causes a large decrease in full-length transcripts and when combined with R117H reduces function to ~1.5% (column 3) and to 0.75% when the other allele is non-functional (column 4). …”

Gene expression across aphid biotypes. by Holly L. Nichols (10702131)

“…Each expressed gene in the aphid genome is represented by a point. The x-axes show the log₂ fold change of each gene, with points to the right side of each plot indicating increased expression in the presence of symbionts, and points to the left showing decreased expression. …”

The relative contribution of TAK1 and MAPK pathways in fibronectin DAMP induced expression of pro-inflammatory genes. by Pranav Maddali (15910220)

“…Fold regulation of gene expression for each cell line was determined using RT-PCR and a list of genes with ≥5-fold decrease in expression compared to control treated cells were generated. …”

Putative Effect of Aquifer Recharge on the Abundance and Taxonomic Composition of Endemic Microbial Communities by Renee J. Smith (204039)

“…Following wastewater addition, a 25-fold decrease in abundance was observed, coinciding with a 12-fold increase in viral abundance. …”

Steady-State NTPase Activity of Dengue Virus NS3: Number of Catalytic Sites, Nucleotide Specificity and Activation by ssRNA by J. Jeremías Incicco (391362)

“…The effect of ssRNA on the ATPase activity of NS3 was studied using poly(A) and poly(C). Both RNA molecules produced a 10 fold increase in the turnover rate constant (<i>k_cat</i>) and a 100 fold decrease in the apparent affinity (<i>K_M</i>) for ATP. …”

Pattern of differential expression of <i>S</i>. Typhimurium sRNAs in the panel of regulatory mutants. by Aoife M. Colgan (3088461)

“…Each circular track represents a single regulatory system. Red boxes indicate putative activation of sRNA expression (>3-fold decrease in expression in mutant compared to wild-type); Blue boxes indicate putative repression of sRNA expression (>3-fold increase in expression in mutant compared to wild-type); yellow indicates no change in expression in mutant compared to wild-type. …”

Data_Sheet_1_Rough-set based learning: Assessing patterns and predictability of anxiety, depression, and sleep scores associated with the use of cannabinoid-based medicine during C... by Sheela Ramanna (8746302)

“…<p>Recently, research is emerging highlighting the potential of cannabinoids' beneficial effects related to anxiety, mood, and sleep disorders as well as pointing to an increased use of cannabinoid-based medicines since COVID-19 was declared a pandemic. The objective of this research is 3 fold: i) to evaluate the relationship of the clinical delivery of cannabinoid-based medicine for anxiety, depression and sleep scores by utilizing machine learning specifically rough set methods; ii) to discover patterns based on patient features such as specific cannabinoid recommendations, diagnosis information, decreasing/increasing levels of clinical assessment tools (CAT) scores over a period of time; and iii) to predict whether new patients could potentially experience either an increase or decrease in CAT scores. …”

Identification of proteins that are differentially expressed in the activated T cells. by Wei-Yun Sheng (261744)

“…The protein spots that displayed at least 2-fold increase or decrease were marked by arrow in panels A–D, and referred to A1-33, B1-15, C1-15, D1-21, respectively. …”

Influence of mentalis muscle relaxation on oronasal breathing by Mara Letícia Gobbis (10445129)

“…The mentalis muscle, in its turn, had in the pre- and post-phase, respectively, a mean (standard deviation) of 199.31 (279.77) µV and 114.58 (253.56) µV. …”

Table_1_Differential Effects of Human SP-A1 and SP-A2 on the BAL Proteome and Signaling Pathways in Response to Klebsiella pneumoniae and Ozone Exposure.xlsx by Guirong Wang (124425)

“…We found: that (1) Ozone exposure, but not infection, is a major factor for increases in total BAL protein content. (2) A total of 36 proteins were identified, accounting for 89.62% of the BAL proteins resolved by the 2D-DIGE system. (3) The number of proteins in which levels were altered more than 25% following infection and FA exposure was: SP-A2 > SP-A1 > KO for male mice, and SP-A2 ≈ SP-A1 > KO for female mice. (4) The number of proteins with more than 25% increase/decrease after ozone exposure and infection was: SP-A2 > SP-A1 ≈ KO, with the majority being increases in male mice and decreases in female mice. (5) Eleven out of the 36 proteins, including annexin A5, glutathione S-transferase A4, SP-A1/SP-A2, and 14-3-3 zeta protein, exhibited significant differences among SP-A genotypes. …”

Late Mesozoic tectonic affinity of the Tengchong Block and southward extension of the Bangong-Nujiang Suture: constraints from Early Cretaceous granitic rocks in western Yunnan, SW... by Chen Wang (88408)

“…The presence of biotite indicative of I-type granite and the observation that P₂O₅ decrease with increasing SiO₂ further indicated that the monzogranites have affinities of I-type granites. …”

Table_2_Differential Effects of Human SP-A1 and SP-A2 on the BAL Proteome and Signaling Pathways in Response to Klebsiella pneumoniae and Ozone Exposure.xlsx by Guirong Wang (124425)

“…We found: that (1) Ozone exposure, but not infection, is a major factor for increases in total BAL protein content. (2) A total of 36 proteins were identified, accounting for 89.62% of the BAL proteins resolved by the 2D-DIGE system. (3) The number of proteins in which levels were altered more than 25% following infection and FA exposure was: SP-A2 > SP-A1 > KO for male mice, and SP-A2 ≈ SP-A1 > KO for female mice. (4) The number of proteins with more than 25% increase/decrease after ozone exposure and infection was: SP-A2 > SP-A1 ≈ KO, with the majority being increases in male mice and decreases in female mice. (5) Eleven out of the 36 proteins, including annexin A5, glutathione S-transferase A4, SP-A1/SP-A2, and 14-3-3 zeta protein, exhibited significant differences among SP-A genotypes. …”

Table_3_Differential Effects of Human SP-A1 and SP-A2 on the BAL Proteome and Signaling Pathways in Response to Klebsiella pneumoniae and Ozone Exposure.xlsx by Guirong Wang (124425)

“…We found: that (1) Ozone exposure, but not infection, is a major factor for increases in total BAL protein content. (2) A total of 36 proteins were identified, accounting for 89.62% of the BAL proteins resolved by the 2D-DIGE system. (3) The number of proteins in which levels were altered more than 25% following infection and FA exposure was: SP-A2 > SP-A1 > KO for male mice, and SP-A2 ≈ SP-A1 > KO for female mice. (4) The number of proteins with more than 25% increase/decrease after ozone exposure and infection was: SP-A2 > SP-A1 ≈ KO, with the majority being increases in male mice and decreases in female mice. (5) Eleven out of the 36 proteins, including annexin A5, glutathione S-transferase A4, SP-A1/SP-A2, and 14-3-3 zeta protein, exhibited significant differences among SP-A genotypes. …”

Association between <em>OLR1</em> K167N SNP and Intima Media Thickness of the Common Carotid Artery in the General Population by Irene Marta Predazzi (185025)

“…Functional analysis on macrophages suggested a decreased association to Ox-LDL in NN carriers compared to KN and KK carriers which is also associated with a reduced <em>OLR1</em> mRNA expression. …”

Prdx6 protein and mRNA levels after paraquat exposure. by Stéphanie Trudel (372065)

“…Indicated values correspond to the ratio of Prdx6 to β-actin mRNA (mean±S.E., n = 8 for saline and n = 5 for PQ, in triplicate). …”

Supplementary Material for: Week 2 Symptomatic Response with Vedolizumab as a Predictive Factor in Japanese Anti-TNFα-Naive Patients with Ulcerative Colitis: A post hoc Analysis of... by Nagahori M. (9991100)

“…Mean percentage decrease from baseline RB subscore was numerically greater with vedolizumab versus placebo from Week 6 in anti-TNFα-naive patients (−10.7%; 95% CI, −33.0, 11.5). …”

A comparison of balance control during stance and gait in patients with inflammatory and non-inflammatory polyneuropathy by Oliver Findling (517065)

“…</p><p>Methods</p><p>Balance control of 11 CIDP patients (mean age 61.1±(sd) 11, 8 male) and 10 non-inf PNP patients (mean age 68.5±11.7, all male) was examined and compared to that of 18 age- and gender-matched healthy controls. …”

Data_Sheet_1_Crystal Structure, Infrared Spectra, and Microwave Dielectric Properties of Ce2(Zr0.94Sn0.06)3(MoO4)9 Ceramics With Low Sintering Temperature.PDF by Huanrong Tian (8880626)

“…The reduced τ_f value could be explained by decrease of the bond energy, enhanced the co-efficient of thermal expansion and increase of bond valence (V_Zr(Sn)). …”

Random forest model results. by Henri A. Thomassen (237544)

“…<p>Higher values of the “mean decrease in accuracy” and the “mean decrease in Gini index” indicate higher predictor variable importance. …”

Random Forest analysis of cohort 2 sample data using 25 metabolites selected from cohort. by Bryan M. Wittmann (679157)