Antimutator Alleles of Yeast DNA Polymerase Gamma Modulate the Balance between DNA Synthesis and Excision by Françoise Foury (196285)

“…These <em>mip1</em> mutations, localised in the 3′-5′ exonuclease and polymerase domains, elicit a 2–15 fold decrease in the frequency of mtDNA point mutations in an <em>msh1-1</em> strain which is partially deficient in mtDNA mismatch-repair. …”

DataSheet_1_Temperature and elevated CO2 alter soybean seed yield and quality, exhibiting transgenerational effects on seedling emergence and vigor.docx by Naflath Thenveettil (19262185)

“…When the growing temperature increased from optimum to high, the seed oleic acids increased (63%), while linoleic and linolenic acids decreased (- 28% and - 43%, respectively). Significant temperature and CO₂ effects were observed in progenies with the highest maximum seedling emergence (80%), lesser time to 50% emergence (5.5 days), and higher seedling vigor from parents grown at low-temperature treatment under eCO₂.…”

Deletion of Gpr177 in embryonic epidermis leads to ablation of Wnt/β-catenin signaling in dermis. by Xiao-Jing Zhu (645748)

“…<p>(A) Quantitative RT-PCR shows a decrease in the expression of <i>Axin2, Dkk1, Fzd1, Lef1, TCF4</i> in limb skin of mutants at E16.5. **, P<0.01, compared to wild type controls. …”

Expression pattern of a <i>puc</i> reporter line in the central brain. by David Kapfhamer (295513)

“…<p><b><i>A</i></b>, Rescue of decreased <i>puc¹/+</i> ethanol-induced locomotor stimulation in the <i>NP1311</i> expression pattern. …”

DataSheet1_pH-Responsive Amphoteric p (APTMACl-co-AMPS) Hydrogel as Effective Multiple Dye Sponge Network From Aqueous Media.docx by Sahin Demirci (8975360)

“…HCl-treated p (APTMACl-co-AMPS) hydrogels prepared in 1:3 mol ratio adsorbed higher amount of MB and EY from their corresponding 50 ml 50 ppm aqueous solutions that are 47.5 ± 0.9, and 10.7 ± 0.1 mg/g, respectively. …”

DataSheet1_The Efficacy and Safety of Pulmonary Vasodilators in Pediatric Pulmonary Hypertension (PH): A Systematic Review and Meta-analysis.docx by Tingting Shu (353149)

“…In total, compared with the control group treatment, pulmonary vasodilators significantly decreased the mortality (p = 0.002), mean pulmonary artery pressure (mPAP, p = 0.02), and mechanical ventilation duration (p = 0.03), also improved the oxygenation index (OI, p = 0.01). …”

WNT enhances acinar progenitor activity through LRP6 signaling. by Lisa M. Arendt (204431)

“…(<b>I, J</b>) WNT1 expression increased acinar colonies, while reduced LRP6 expression diminished acinar colonies, when WNT1, EV, shscram, and shLRP6 expressing MECs were grown as mammospheres (<b>I</b>) or floating colonies (<b>J</b>) prior to plating on collagen (n = 5 patient samples; mean±s.e.m.). (<b>K</b>) TBX3 MCF10A cells demonstrated significantly increased expression of <i>WNT2B</i> and <i>WNT9A</i> compared with EV cells. …”

Genomic Analysis of the Function of the Transcription Factor <em>gata3</em> during Development of the Mammalian Inner Ear by Marta Milo (232638)

“…Expression levels estimated by this method correlated closely (p<0.0001) across a 10-fold range with those measured by quantitative RT-PCR for a sample of 61 different genes. …”

Video_1_Acupressure versus parecoxib sodium in acute renal colic: A prospective cohort study.MP4 by Chiwei Chen (13844319)

“…The acupressure group obtained lower VAS scores at the 1st, 5th, 10th, and 20th minute than the parecoxib sodium group after initiating the intervention (mean: 4.33 vs. 7.61, mean difference (MD): 3.29, 95% CI: 0.23, 2.84; mean: 2.65 vs. 7.61, MD: 4.96, 95% CI: 4.44, 5.49; mean: 1.63 vs. 6.59, MD: 4.96, 95% CI: 4.48, 5.44; mean: 1.26 vs. 3.64 MD: 2.38, 95% CI: 1.87, 2.88; P < 0.05). …”

Table_1_Giant cell temporal arteritis: a clinicopathological study with emphasis on unnecessary biopsy.pdf by Hind M. Alkatan (11592654)

“…The mean diagnostic clinical score used in our study was higher (7.5 ± 2.33) in the GCA-positive group when compared to the other groups with statistical significance (mean of 4.85 ± 2.01 in patients with overall GCA-negative biopsies and 5.13 ± 2.10 in the group with atherosclerosis). …”

Image1_The clinical and genetic aspects of six individuals with GH1 variants and isolated growth hormone deficiency type II.tif by Xiaozhen Huang (5858690)

“…All children demonstrated GH deficiency in growth hormone stimulation tests (mean peak GH value: 2.83 ± 2.46 ng/mL). Exome sequencing for the six patients and targeted gene sequencing for their family members revealed heterozygous variants in the GH1 gene, including Exon2-5del, c.334T>C, c.291 + 1G>A, c.291 + 2T>A, 1.5 kb deletion, and 1.7 kb deletion, with four variants being novel. …”

Table1_The clinical and genetic aspects of six individuals with GH1 variants and isolated growth hormone deficiency type II.docx by Xiaozhen Huang (5858690)

“…All children demonstrated GH deficiency in growth hormone stimulation tests (mean peak GH value: 2.83 ± 2.46 ng/mL). Exome sequencing for the six patients and targeted gene sequencing for their family members revealed heterozygous variants in the GH1 gene, including Exon2-5del, c.334T>C, c.291 + 1G>A, c.291 + 2T>A, 1.5 kb deletion, and 1.7 kb deletion, with four variants being novel. …”

The Effect of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) on Erectile Function: A Systematic Review and Meta-Analysis by Xiang Chen (10398)

“…A significant decrease in the IIFE-5 score was observed in the CP/CPPS group (pooled mean difference: −4.54, 95% CI: −5.11–−3.98; <i>P</i> < 0.01).…”

Multiple modes of modulation of PC simple spikes during light activation of ChR2 specifically expressed in GCs. Light activation of GCs results in inhibition and/or activation of P... by Wolfgang Kruse (619565)

“…Laser power was set to 10 mW, resulting in 2.5 mW in front of light fiber. (E) Mean increase of simple spike rate from 13 PCs showing excitation during light application and mean decrease of activity of 12 PCs showing inhibition during light application. …”

Associations between initial neutralizing antibody potency and rate of declining neutralization potency over time. by Lindsay Wieczorek (171734)

“…A positive fold change in Env sensitivity to a given NAb indicates increasing sensitivity (earlier PSV GM IC₅₀ > later PSV GM IC₅₀), while a negative fold indicates decreasing sensitivity over time (earlier PSV GM IC₅₀ < later PSV GM IC₅₀). …”

Experiment 2a. by Jiehui Qian (294581)

“…<p>a) Two lines were presented during the 30-s adaptation phase; two bars were shown during the afterimage phase. b) Left: the dark green bar indicates the mean illusory decrease of the lower bar length in Experiment 2a, 9.19%. …”

DataSheet_1_Phytoplankton photophysiology varies depending on nitrogen and light availability at the subsurface chlorophyll maximum in the northern Chukchi Sea.docx by Eunho Ko (14004480)

“…The maximum quantum yield of photochemistry in photosystem II (F_v/F_m) in the SCM phytoplankton was high (F_v/F_m ≥ 0.54) and similar in both regions until 2016; however, since then, F_v/F_m in the northeastern Chukchi Sea has decreased by approximately 10%. This decrease was accompanied by a marked decrease in the fraction of microplankton, which are known to be susceptible to nutrient limitation. …”

Dataset. by Valéria Teresa Saraiva Lino (20390441)

“…In the intervention group, there was a significant decrease in the likelihood of violence against the elderly, with a 10-fold reduction. …”

CONSORT flow diagram. by Valéria Teresa Saraiva Lino (20390441)

“…In the intervention group, there was a significant decrease in the likelihood of violence against the elderly, with a 10-fold reduction. …”

Fig 4 - by Annie M. Westerlund (5051915)

“…The decreased distance between the V108-F141 residues in S₇ is highlighted with a black circle/ <b>(C)</b> Distance between center-of-mass of the N97 and E104 residues making up the Ca²⁺ binding site within the S₅, S₆ and S₇ macrostates. …”