Ten-Year Mortality and Cardiovascular Morbidity in the Finnish Diabetes Prevention Study—Secondary Analysis of the Randomized Trial by Matti Uusitupa (89892)

“…<div><h3>Background</h3><p>The Finnish Diabetes Prevention Study (DPS) was a randomized controlled trial, which showed that it is possible to prevent type 2 diabetes by lifestyle changes. …”

Phosphorylation changes in GRP78 during sperm maturation by Vivian Lobo (831560)

“…</p><p></p><p></p><p>In the mature sperm, a) GP_4.85 and GP_4.96 are resistant to λ- PP but responsive to CIP, b) GP_4.94 decreases significantly and a new GRP78 phosphoform GP_4.85 emerges. …”

Data Sheet 1_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e... by Yin Huang (179237)

“…Celigo counting revealed a significant decrease in both cell lines after 24–96 h of CEP treatment. …”

Image_1_Gegen Qinlian Decoction Coordinately Regulates PPARγ and PPARα to Improve Glucose and Lipid Homeostasis in Diabetic Rats and Insulin Resistance 3T3-L1 Adipocytes.pdf by Jun Tu (802496)

“…<p>Gegen Qinlian Decoction (GQD), a well-documented traditional Chinese Medicine (TCM) formula, was reported with convincing anti-diabetic effects in clinical practice. …”

DataSheet3_Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer.xlsx by Emily M. J. Fennell (6654536)

“…GO analysis of these data demonstrated additional similarity of response to ONC201 and TR-57, including a decrease in transcripts related to the mitochondrial inner membrane and matrix, cell cycle, and nucleus, and increases in other nuclear transcripts and transcripts related to metal-ion binding. …”

Image_1_Reduced serum IgG galactosylation is associated with increased inflammation during relapses of neuromyelitis optica spectrum disorders.tif by Shiyu Gao (772659)

“…</p>Results<p>In the context of NMOSD relapses, serum IgG galactosylation exhibited a notable decrease in untreated patients (0.2482 ± 0.0261), while it remained comparatively stable in medicated patients when contrasted with healthy controls (0.3625 ± 0.0259) (p=0.0159). …”

Basal PLD activity is strongly stimulated by the D1/5R agonist and blocked by the D1/5R, mGluR5, mGluR1, and the PLD-linked mGluR antagonists in the amygdala of cocaine CPP animals... by Balaji Krishnan (203728)

“…The D1/5R antagonist, SCH23390, completely blocked basal PLD activity (91.2±21.9, n = 12, ^##<i>p</i><0.01) in the cocaine CPP group. A similar reduction in PEtOH levels was observed with application of either the PLD-linked mGluR antagonist, PCCG-13 (62.9±10.6, n = 7, ^##<i>p</i><0.01) or the mGluR1 antagonist, LY367385 (75.0±13.9, n = 12, ^##<i>p</i><0.01), while the mGluR5 antagonist, MPEP, did not decrease basal PLD activity (305.7±31.5, n = 7, ns) within the cocaine CPP group but were significantly increased compared to (*<i>p</i><0.05) the saline treated group. …”

Image_1_Archetypal type II and III Toxoplasma gondii oocysts induce different immune responses and clinical outcomes in experimentally infected piglets.tif by Andrea Largo-de la Torre (13985607)

“…Apathy and a moderate decrease in feed consumption were observed in G1 and G2 piglets between 5 and 8 dpi, coinciding with fever (>40°C). …”

Table_2_Systemic immunological profile of children with B-cell acute lymphoblastic leukemia: performance of cell populations and soluble mediators as serum biomarkers.docx by Maria Perpétuo Socorro Sampaio Carvalho (7300568)

“…On D8 and D15, the patients presented a transition in the immunological profile. While, on D35, they already presented an opposite profile to D0, with an increase in NKT, CD3⁺ T, CD4⁺ T and Treg cells, along with CCL5, and a decrease in the levels of CXCL9, CXCL10 and IL-10, thus demonstrating that B-ALL patients present a complex and dynamic immune network during induction therapy. …”

DataSheet7_Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer.xlsx by Emily M. J. Fennell (6654536)

“…GO analysis of these data demonstrated additional similarity of response to ONC201 and TR-57, including a decrease in transcripts related to the mitochondrial inner membrane and matrix, cell cycle, and nucleus, and increases in other nuclear transcripts and transcripts related to metal-ion binding. …”

Image2_Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer.JPEG by Emily M. J. Fennell (6654536)

“…GO analysis of these data demonstrated additional similarity of response to ONC201 and TR-57, including a decrease in transcripts related to the mitochondrial inner membrane and matrix, cell cycle, and nucleus, and increases in other nuclear transcripts and transcripts related to metal-ion binding. …”

Lanthanide Metalloligand Strategy toward d–f Heterometallic Metal–Organic Frameworks: Magnetism and Symmetric-Dependent Luminescent Properties by Xiao-feng Huang (1791529)

“…It is worth noting that, in <b>2d</b>, the intensity ratio <i>I</i>(⁵D₀→⁷F₁)/<i>I</i>(⁵D₀→⁷F₂) could decrease significantly upon the introduction of different hydrophilic guest molecules, which implies that the luminescent properties of <b>2d</b> have a strong dependence on the geometry of the first coordination sphere of the Eu^III ion.…”

Image_2_Comparison of long-term cardiovascular and renal outcomes between percutaneous coronary intervention and coronary artery bypass grafting in multi-vessel disease with chroni... by Woochan Kwon (13772311)

“…However, PCI-CR had a comparable 5-year death, MI, or stroke rate to CABG (HR: 0.86, 95% CI 0.54–1.38, p = 0.54).…”

Image6_Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer.JPEG by Emily M. J. Fennell (6654536)

“…GO analysis of these data demonstrated additional similarity of response to ONC201 and TR-57, including a decrease in transcripts related to the mitochondrial inner membrane and matrix, cell cycle, and nucleus, and increases in other nuclear transcripts and transcripts related to metal-ion binding. …”

Stit and InR cooperatively govern TORC1 activity. by Fergal O'Farrell (435865)

“…<p>Anti-p-dS6K labeling of third instar larval wing discs revealed discrete puncta lying basally within cells. See <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001612#pbio.1001612.s005" target="_blank">Figure S5</a> for control experiments addressing labeling specificity. …”

Principle of the Amplex Red assay of HDL function. by Theodoros Kelesidis (698171)

“…As a result, in the basal state, HDL may be considered anti-oxidant. …”

Table_2_Spatial-temporal analysis of hepatitis E in Hainan Province, China (2013-2022): insights from four major hospitals.XLSX by Zhi Yun (2139964)

“…The annual incidence of hepatitis E increased from 2013 to 2019, with a slight decrease in 2020 and 2021 and an increase in 2022. …”

Surface targeting distinguished VE-2B from VE-2BΔ7. by Steve Standley (155721)

“…VE-2BΔ7 surface pixel overlap with synapsin trended toward a decrease compared to VE-2B at 2X background but not significantly until thresholded at 3X background (one-way Anova, <i>post hoc</i> comparison p<0.05). …”

Table_5_Spatial-temporal analysis of hepatitis E in Hainan Province, China (2013-2022): insights from four major hospitals.XLSX by Zhi Yun (2139964)

“…The annual incidence of hepatitis E increased from 2013 to 2019, with a slight decrease in 2020 and 2021 and an increase in 2022. …”

Table_4_Spatial-temporal analysis of hepatitis E in Hainan Province, China (2013-2022): insights from four major hospitals.XLSX by Zhi Yun (2139964)

“…The annual incidence of hepatitis E increased from 2013 to 2019, with a slight decrease in 2020 and 2021 and an increase in 2022. …”