Ptch1 Inhibits Smo Intercellularly by Maarten F Bijlsma (380371)

“…Intercellular capacity of Ptch1 to inhibit Smo was assessed by mixing reporter cells overexpressing Smo and a Gli reporter with Ptch1-overexpressing donor cells. The observed decrease in Gli reporter activity could not be inhibited by the addition of 1 μg/ml 5E1 Shh-blocking antibody. …”

Image_2_Ethnic and Sociocultural Differences in Ovarian Reserve: Age-Specific Anti-Müllerian Hormone Values and Antral Follicle Count for Women of the Arabian Peninsula.jpg by Laura Melado (3990398)

“…</p>Results<p>2,495 women were evaluated. Mean, standard deviation and median values were calculated for AMH and AFC by 1-year and 5-years intervals. …”

Table_2_Ethnic and Sociocultural Differences in Ovarian Reserve: Age-Specific Anti-Müllerian Hormone Values and Antral Follicle Count for Women of the Arabian Peninsula.docx by Laura Melado (3990398)

“…</p>Results<p>2,495 women were evaluated. Mean, standard deviation and median values were calculated for AMH and AFC by 1-year and 5-years intervals. …”

Exocrine gland dysfunction in matriptase-deficient mice. by Hongen Yin (351667)

“…(B, D) AAV2-mediated acute deletion of matriptase led to a significant decrease in SFR in AAV2-Cre animals (<i>N = </i>17) compared with the AAV2-LacZ controls (<i>N = </i>17) 5–6 weeks after AAV2 administration (*<i>P</i> = 0.0126). …”

ST266 attenuates RGC loss in mice with mild-moderate EAE optic neuritis. by Keirnan Willett (9946075)

“…Data shown as mean +SEM.</p>…”

Changes in bone architecture in <i>Lmna</i>^−/− mice. by Wei Li (7081)

“…The distance between two layers of tetracycline labels (<i>arrows</i>) visualized by epifluorescence represents bone formation that occurred during the 5-d period between tetracycline injections. Mutant mice showed a significant decrease in all parameters of bone formation including mineralized surface/bone surface (MS/BS), mineral apposition rate (MAR) and bone formation rate/bone surface (BFR/BS) as compared with their WT littermates (*<i>P</i><0.001). …”

Dose planning study of proton versus photon radiotherapy for head and neck squamous cell carcinoma of unknown primary in the primary and recurrent setting by Anne Ivalu Sander Holm (3996290)

“…However, using protons for re-irradiation only leads to a decrease in the tissue volume receiving a specific dose outside the target overlapping region, e.g., V90Gy_mean was 31, 25, and 22 cm³ for photons-photons, photons-protons, and protons-protons, respectively. …”

The NOD1 agonist iE induces NF-κB activation and apoptosis in cardiomyocytes and H9c2 cells. Effect of NOD1 ablation with siRNAs. by María Fernández-Velasco (105894)

“…Data are expressed in histograms representing the mean±SEM <i>vs</i>. vehicle (100%); n = 3–5 samples per condition.…”

High-intensity focused ultrasound (HIFU) therapy for benign thyroid nodules: a 3-year retrospective multicenter follow-up study by Hervé Monpeyssen (9672810)

“…Complications and side effects were classified according to the Interventional Radiology Guidelines and changes in local symptoms were scored on a visual-analog scale.</p> <p> Sixty-five patients (mean age 51.1 ± 14.0 years; 86.2% women) with a single thyroid nodule and a mean baseline nodule volume of 9.8 ± 10.3 mL were treated with a mean energy of 7.1 ± 3.1 kJ (range: 2.0 to 15.5 kJ). …”

Infiltration of blood clots by cancer cells. by Stephanie Rossnagl (553093)

“…(F) Evaluation of cancer cell numbers when injected 5 minutes after clot induction showed a significant decrease in the number of cancer cells detected in the bone marrow at 1 hour after clot induction (p<0.05) but not at later time points (4, 24 and 48 hours after clot induction) (p = ns). n = 4–8 per time point.…”

Loss of OPCs starts during the first postnatal week in the corpus callosum after genetic ablation of <i>C1ql1</i>-expressing OPCs. by Shayan Moghimyfiroozabad (19066182)

“…Data are represented as mean ± SEM. <i>C1ql1</i>^<i>wt</i><i>; Sox10</i>^<i>DTA</i>: <i>n</i> = 3–5 animals. …”

<i>In vivo</i> Sema3C treatment prevents O₂-induced arrested vascular growth. by Arul Vadivel (424484)

“…B. Mean data quantifying the number of vWF positive vessels between groups. …”

Effect of testosterone supplementation plus low-intensity physical training on mitochondrial quality control in skeletal muscle. by Wen Guo (112664)

“…N = 5 for the control (C) group and 8 for the testosterone (T) group (for visual clarity, only five are displayed in Western blots).…”

Overall influence of the levels of stimulation on behavioral thresholds and latencies. by Ivanne Pincedé (270921)

“…On average, the behavioral threshold T_R was 46.7 (45.9-47.5)°C with a non-significant tendency to decrease from the proximal to the distal parts of the tail. …”

ATRA treatment induces expression of S100 and inhibits PMP22 expression. by Susan Fischer-Huchzermeyer (4588522)

“…<p>Flow cytometry analysis (FACS) of S100 and PMP22 protein expression in ATRA treated MPNST cells on day 7 of treatment (5μM). Bars indicate increase or decrease of fluorescence intensity (%) compared to untreated controls (100%). …”

A comprehensive model for insulator-mediated nuclear localization. by Hua-Bing Li (403974)

“…Polycomb bodies, visualized with anti-PSC (red), decrease in number and size, mostly losing the weaker foci. …”

Relative uncertainty and filtering of the power spectrum. by Maximilian Witte (8313381)

“…The number of remaining pixels after filtering as well as the error of the uncertainty calculation compared to the Monte-Carlo simulation Δ_MC is shown in (J). The mean error, its standard deviation (<i>grey</i> shaded areas) as well as the number of remaining pixels gradually decrease towards a lower threshold <i>δ</i>_cut. …”

Soy isoflavones genistein and daidzein protect primary cortical cultures from Tat neurotoxicity. by Sheila M. Adams (322032)

“…Data represents mean values ± SEM, n of cultures analyzed  = 7–12 per each group. *- indicates significant (<i>p</i>≤0.05) protective effects of the selected compounds against Tat neurotoxicity (cell viability decrease) in cortical cell cultures. …”

The GePPI screen identifies Elm1 as involved in the regulation of SBF by Cdc28. by Emily N. Manderson (272555)

“…<p>(A) Changes in average mean pixel intensity for the three PCAs: Cdc28-Swi4, Cdc28-Swi6 and Cdc28-Mbp1, in the 30 deletion strains. …”

Effect of various intracellular ROS inhibitors on the [Ca²⁺]_i transient elevation induced by extracellular ATP. by Duo-ling Li (523730)

“…<p>A, C, time series of the mean F ratio during the application of different agents. …”