Myosin phosphatase and RhoA-activated kinase modulate neurotransmitter release by regulating SNAP-25 of SNARE complex by Dániel Horváth (4015034)

“…In response to the transduction of the MP inhibitor, kinase-enhanced PP1 inhibitor (KEPI), into synaptosomes, an increase in phosphorylation of SNAP-25 and a decrease in the extent of neurotransmitter release were detected. …”

APP Intracellular Domain Impairs Adult Neurogenesis in Transgenic Mice by Inducing Neuroinflammation by Kaushik Ghosal (244754)

“…<div><p>Background</p><p>A devastating aspect of Alzheimer's disease (AD) is the progressive deterioration of memory due to neuronal loss. …”

KChIP2 KD associates with a relocalization of presenilin 1 away from sarcomeric structures. by Drew M. Nassal (845780)

“…Preservation of the average intensity reflects no change in the amount of presenilin protein, however, a decrease in variance reflects the loss in organization for presenilin 1 protein expression upon KChIP2 KD. …”

<i>In Vitro</i> Mutational and Bioinformatics Analysis of the M71 Odorant Receptor and Its Superfamily by Jaclyn Bubnell (461908)

“…Finally, we observed specific increases in methionine and histidine residues as well as a marked decrease in tryptophan residues, suggesting that these changes provide ORs with special characteristics needed for them to function in olfactory neurons.…”

Questionnaire results. by Alexander Neugebauer (2425123)

Arachidonic and Linoleic Acid Derivatives Impact Oocyte ICSI Fertilization – A Prospective Analysis of Follicular Fluid and a Matched Oocyte in a ‘One Follicle – One Retrieved Oocy... by Przemysław Ciepiela (701377)

“…</p><p>Methodology</p><p>Study was designed as a two center (a university clinic and a private clinic) prospective study. 54 women of 181 consecutive couples undergoing ICSI were prospectively found to be eligible for analysis. …”

Impaired expression of <i>bmp4</i>, <i>fgf8a, and1</i> and <i>msx</i> genes in the pectoral fin region of <i>dlx5a/6a</i> morphants. by Églantine Heude (568153)

“…In contrast to what is observed in controls at 48 hpf, <i>dlx5a/6a</i> morphants show a marked decrease or loss of expression of the PFB markers associated with pectoral fin agenesis (B′–D′, F′, H′). …”

Supplementary Material for: Exceptional response to pembrolizumab for treatment of metastatic chemorefractory endometrial carcinoma in a patient with Lynch Syndrome: A case report by Batman S. (15242707)

“…She was then treated with single-agent pembrolizumab and had an exceptional response. She was noted to have a significant decrease in the size of a large uterine mass extending into the vagina and vulva, as well as decrease in the size of lymphadenopathy. …”

Osteohistology of the mid-diaphyseal humerus of <i>Tenontosaurus</i> in a juvenile (A, B), subadult (C, D) and adult (E, F). by Sarah Werning (328210)

“…<p><b>A.</b> Cross-section of OMNH 10144. This bone was invaded by bacteria before fossilization and thus much of the primary tissue is obscured. …”

Structure-Function Analysis of the Transmembrane Protein AmpG from <i>Pseudomonas aeruginosa</i> by Peizhen Li (129618)

“…The G29A, G29V, A129V, A197S and A197D mutants had decreased <i>ampG</i> mRNA transcript levels. …”

Directed virus against CRF infused into the amygdala of ‘floxed’ <i>Grin1</i> mice significantly disrupts <i>GRIN1</i> with no significant effects on CRF. by Georgette Gafford (650138)

“…RTPCR conducted on f<i>Grin1</i> mice that received unilateral CeA infusion of LV pCRF-Cre virus show a significant decrease in (<b>C</b>) <i>Grin1</i>, but not (<b>D</b>) <i>CRF</i> expression in the CeA. …”

Progressive muscle degeneration is prevalent upon a loss of NUAK. by David Brooks (5369636)

“…(H) Scatter plot reveals a decrease in locomotor ability upon <i>NUAK RNAi</i> compared to <i>GFP RNAi</i> controls. …”

Supplementary Material for: Unisex and Sex-Specific Prescriptive Fetal Growth Charts for Improved Detection of Small-for-Gestational-Age Babies in a Low-Risk Population: a post hoc... by vanRoekel M. (19231318)

“…Introduction Our aim was to develop and evaluate the performance of population-based sex-specific and unisex prescriptive fetal abdominal circumference growth charts in predicting small-for-gestational-age (SGA) birthweight, severe SGA (sSGA) birthweight and severe adverse perinatal outcomes (SAPO) in a low-risk population. Methods This is a post hoc analysis of the Dutch nationwide cluster-randomised IRIS study, encompassing ultrasound data of 7,704 low-risk women. …”

Durability of IgG3 responses. by LaTonya D. Williams (3140490)

Display of segmentation effects of structural planes using various methods: (a) Original image; (b) U²-Net segmentation; (c) Global Maximum Threshold Method for Segmenta... by Qingjun Yu (1649473)

Visual training tasks. by Alexander Neugebauer (2425123)

Inhibition of the FOXA Transcription Factor <i>pha-4</i> Decreases Autophagy in <i>eat-2</i> and <i>rab-10</i> Mutants by Malene Hansen (10367)

“…Feeding mutants for several generations with <i>pha-4</i> dsRNA, inhibited development and sharply decreased the number of eggs laid ([<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0040024#pgen-0040024-b046" target="_blank">46</a>], data not shown). …”

RA decreases <i>EDN3</i> and <i>Ece1</i> mRNA levels, depending on whether exogenous EDN3 is present. by Jonathan M. Gisser (456149)

“…(A) At 3 days, RA was associated with a net decrease in the level of <i>EDN3</i> in the absence and presence of exogenous EDN3 (C) Similarly, RA was associated with a decrease in the relative abundance of <i>Ece1</i>, albeit only in the presence of EDN3 After 14 days, RA still decreased the relative abundance of <i>EDN3</i> (B) and <i>Ece1</i> (D) mRNA.…”

Navigation task visualisation. by Alexander Neugebauer (2425123)

Obstacle course schematic. by Alexander Neugebauer (2425123)