Dysregulation of systemic and mucosal humoral responses to microbial antigens in HIV-1-infected individuals. by Zdenek Hel (337869)

“…Epithelial cell apoptosis and decreased availability of antigen-specific IgG and IgA in mucosal secretions result in enhanced translocation of microbial products and whole bacteria across the intestinal mucosal barrier into the systemic circulation.…”

Hemostatic abnormalities in COVID-19: A guided review by PLÍNIO C. SATHLER (10365401)

“…These studies have shown that a portion of the patients affected by Coronavirus Disease 2019 (COVID-19) have prolonged prothrombin time (PT) and activated partial thromboplastin time (APTT), elevated D-dimer levels and other fibrinolytic products, antithrombin (AT) activity reduced and decrease of platelet count. …”

Data_Sheet_1_In vitro study of ATP1A3 p.Ala275Pro mutant causing alternating hemiplegia of childhood and rapid-onset dystonia-parkinsonism.pdf by Dan-dan Ruan (12508987)

“…</p>Conclusion<p>This study reveals that the p.Ala275Pro mutant decreases ATP1A3 protein expression and Na⁺/K⁺-ATPase activity. …”

Atomic charge differences among IMMS-TLR8 interacting atoms under bound and unbound conditions. by Carlos Kubli-Garfias (310635)

“…<p>Most of the IMMS atoms (left panel) were polarized by the binding process, increasing and decreasing their charge values. Thus, N3, N5 and N11 polar pharmacophore atoms, along with C4 and C5a, showed a high polarization characteristic. …”

Comparison of COVID-19 case numbers on days with (coloured) and without (grey) wastewater detection of SARS-CoV-2 RNA. by Jay C. Bullen (10232606)

IL-17+ cell expansion requires Dectin-2 and is relevant in fungal elimination in the early stages of experimental CBM. by Isaque Medeiros Siqueira (3875767)

“…<p>Frequency of IL-17+ T cells is strongly decreased in dLN and footpad of Dectin-2 KO mice (<b>A</b>). …”

Impaired male germline development due to simultaneous loss of RMI2 and RTEL1. by Sarah Röhrig (3228492)

“…<p>(A) By crossing <i>rmi2-2 rtel1-1</i> with wild-type plants (n = 12), practically no seeds could be obtained using pollen from <i>rmi2-2 rtel1-1</i> mutants for crossbreeding. …”

Reduction of Treg population is related to fungus persistence in infected tissue and opposes self-healing in murine experimental CBM. by Isaque Medeiros Siqueira (3875767)

“…<p>Low frequency of active CD4+ T lymphocytes expressing Foxp3 of animals treated with α-CD25 or control isotype (IC) is shown in popliteal lymph node and footpad (<b>A</b>). Frequency of IL-17+ T cells is decreased in dLN of animals treated with αCD25 after 21 and 28 days of infection (<b>B</b>). …”

Galectin‑9 Signaling Drives Breast Cancer Invasion through Extracellular Matrix by Dharma Pally (7216271)

“…Signaling experiments and unbiased quantitative proteomics revealed Galectin-9 induction of Focal Adhesion Kinase activity and S100A4 expression, respectively. FAK inhibition decreased S100A4 mRNA levels. …”

Class membership evaluation for a three-category example. by Remus Oşan (25703)

“…D) Color plots indicating the distribution of probabilities throughout a region containing all data points. Each shade in the color gradation indicates an increase/decrease in probability above the chance levels (grey shade represents equal low probability for all three classes). …”

The SsdC mutant is defective in both germination and heat-resistance. by Johana Luhur (9767765)

“…<p><b>(A)</b> Phase-contrast micrographs of heat-treated (80°C, 20 min) wild-type (bAT87, WT) and Δ<i>ssdC</i> (bJL56) spores during a germination and outgrowth time-course in nutrient-rich media (LB). …”

Cannabidiol effects on behaviour and immune gene expression in zebrafish (<i>Danio rerio</i>) by Hannah M. Jensen (5574980)

“…CDB treatment of zebrafish for 30 min affected mobility of the fish by decreasing swimming speed and swimming distance. In addition, out of 23 immune related genes studied it was shown that expression of two genes <i>il1b</i> and <i>il17a/f2</i> were up-regulated and four genes, <i>tgfba</i>, <i>ighm</i>, <i>cd4-1</i>, and <i>s100a10b</i> were significantly down-regulated following CBD treatment. …”

Experimental and Theoretical Studies on the Platinum-Mediated Selective C(sp)–Si Bond Cleavage of Alkynylsilanes by Yasuhiro Okuda (1591588)

“…A series of <i>cis</i>-alkynyl­(silyl)­platinum­(II) complexes was prepared via the chemoselective C­(sp)–Si bond cleavage of alkynylsilanes by a platinum(0) complex ligated with the P–N hemilabile bidentate ligand. …”

Fig 4 - by Hyun-Jun Kim (1561153)

“…<p>A) qPCR analysis of <i>Pax7</i>, <i>Myf5</i>, <i>Myod</i>, <i>Myog</i> and <i>Myh2</i> expression in differentiating C2C12 myoblasts treated with 150 nM, 300 nM or 600 nM Ni for 24 h. * = <i>p</i><0.05, ** = <i>p</i><0.01 and *** = <i>p</i><0.001 indicate significantly increased or decreased expression compared to untreated myoblasts. …”

Preventing HIV and HSV-2 through knowledge and attitudes: A replication study of a multi-component community-based intervention in Zimbabwe by Fang Yu (156838)

“…While the original intervention targeted knowledge and attitudes as a mechanism to decrease HIV/HSV-2, the Cowan study evaluated the intervention effects on knowledge, attitudes, and prevalence of HIV or HSV-2 separately. …”

Brassinosteroid Regulates 3‑Hydroxy-3-methylglutaryl CoA Reductase to Promote Grape Fruit Development by Ting Zheng (608653)

“…BRs can negatively regulate the expression of <i>VvHMGR</i>, a key gene involved in the mevalonate (MVA) pathway, and reduce the activity of 3-hydroxy-3-methylglutaryl CoA reductase (HMGR). …”

Hsc70-4 is required to prevent protein aggregation. by David Brooks (5369636)

“…<p>(A) Table showing prey proteins that interact with Stv in a Y2H screen. …”

Loss of function mutations in essential genes cause embryonic lethality in pigs by Martijn F. L. Derks (5348063)

“…The lethal haplotypes have a large effect on carrier-by-carrier matings, decreasing litter sizes by 15.1 to 21.6%. …”

Overexpression of phosphomimetic eIF4E-S209D does not affect proliferation but increases clonogenic cell survival. by Alba Martínez (732002)

“…<p>A, Western blot analysis showed similar, moderate levels of Myc-tagged exogenous eIF4E-S209D or-S209A and endogenous eIF4E expression in MDA-MB-231 and HaCaT cell lines. …”

Response to capsaicin. by Rachel Wilson (605761)

“…<p><b>Panel A</b>, Time course of Fluo-4 intensities before and after addition of Fluo-4. …”