Proportion of time spent in the Start Room or Avoidance Room or showing a behaviour (Stimulus Contact) presented across stimuli and separately for female (n = 10) and male (n = 10)... by Sara Hintze (3216885)

Safranin O fast green staining results of cartilage tissue in different groups of rat PTOA (A: normal group, B: mild PTOA group, C: severe PTOA group). by Peng-fei Han (694841)

Datasheet1_Multicenter review of a tadalafil suspension formulation for infants and children with pulmonary hypertension: A North American experience.pdf by David Edward Youssef (14501636)

“…Tadalafil is a PDE5 inhibitor with a long half life (16 h), stable pharmacokinetics and pharmacodynamics, and minimal adverse effects. …”

Cellular and Matrix Response of the Mandibular Condylar Cartilage to Botulinum Toxin by Eliane H. Dutra (3207312)

“…There was no significant difference in the mandibular length and condylar head length; however, the condylar width was significantly decreased after Botox injection. Our histology showed decreased numbers of Col10a1 expressing cells, decreased cell proliferation and increased cell apoptosis in the subchondral bone and mandibular condylar cartilage, decreased TRAP activity and mineralization of Botox injected side cartilage and subchondral bone. …”

Clinical endpoints in the controlled human challenge model for <i>Shigella</i>: A call for standardization and the development of a disease severity score by Chad K. Porter (2552560)

“…An ordinal disease score characterizing the breadth of disease severity may enable a better characterization of shigellosis and can decrease sample size requirements. …”

Use of a platelet-rich plasma-collagen scaffold as a bioenhanced repair treatment for management of partial cruciate ligament rupture in dogs by Susannah J. Sample (308203)

“…This study tested the hypothesis that treatment of partial stable CR stifles with an intra-articular collagen scaffold and PRP would decrease the disease progression, synovitis and risk of complete CR over a 12-month study period. …”

Potential interplay between Aβ oligomers, Ca²⁺, and a target cell in the initial stages of Alzheimer's disease. by Anna Itkin (354170)

“…Aβ oligomers can affect surface expression of N-methyl-D-aspartate receptors (NMDARs) <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0018250#pone.0018250-Dewachter1" target="_blank">[67]</a>, may increase <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0018250#pone.0018250-Molnr1" target="_blank">[68]</a> or decrease the conductance <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0018250#pone.0018250-Shankar1" target="_blank">[69]</a>, and facilitate long-term synaptic depression by disrupting neuronal glutamate uptake <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0018250#pone.0018250-Li1" target="_blank">[70]</a>.…”

Fig 5 - by Hyun-Jun Kim (1561153)

“…C-D) Quadriceps and gastrocnemius muscle mass in the treated mice. For A-D) * = <i>p</i><0.05 and ** = <i>p</i><0.01, indicate significantly decreased compared to the vehicle control. …”

Fig 2 - by Hyun-Jun Kim (1561153)

“…<p>A) Representative images of myosin heavy chain immunostained C2C12 myotubes after treatment with Dex and Ni (scale bar = 100 μm). …”

Dysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease by Tommy Pacana (790420)

“…Although gene expression of the DNA methyltransferase <i>Dnmt3a</i> decreased, the global DNA methylation was unaltered. …”

Time kill kinetics of WSWE against <i>S</i>. <i>globosa</i>. by Acharya Balkrishna (5640038)

Maximum blood glucose and serum insulin concentrations (geometric mean and 95% CI) measured over 4 h after feeding a meal high in non-structural carbohydrates comparing control pon... by Alexandra Meier (5746292)

ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type by Luca Schifanella (6694940)

“…High Alum dosage, in contrast, elicited serum IgG to V2 that correlated with a decreased risk of Tier 1 SHIV-C acquisition. …”

Replication of interacting SNP pairs between populations. by Benjamin Goudey (556759)

“…<p>Overlap of significant pairs as a percentage between UK1 and remaining cohorts in order of decreasing GSS significance. …”

Retinoids induce antagonism between FOXO3A and FOXM1 transcription factors in human oral squamous cell carcinoma (OSCC) cells by Kwame Osei-Sarfo (6585389)

“…Overexpression of <i>FOXO3A</i> decreased proliferation and increased binding of histone deacetylases (HDACs) 1 and 2 at the <i>FOXM1</i>, <i>AURKB</i>, and <i>VEGFA</i> promoters. …”

Fig 6 - by Hyun-Jun Kim (1561153)

“…<p>A-C) Representative crystal violet assay for A549, HCT-116, and PANC-1 cells treated with Ni for 48 h. …”

Plasma SCFA and dietary fiber intake. by Pieter F. de Groot (4666828)

“…<p>The figure shows that (A) despite higher fiber intake, we (B) found decreased plasma levels of acetate and (C) propionate and (D) similar levels of plasma butyrate in controls vs T1D subjects.…”

Cell line copy number and protein expression. by Ting-Ting Liu (585803)

“…<p>(a) Compared to the RBE cell line, copy numbers in the SNU1079 cell line was decreased. …”

FFA treatment for 48 hours induced autophagy response in Huh-7.5 cells. by Ramazan Kurt (449801)

“…The expression of p62 was decreased by both HCV and FFA treated culture. The expression of ATG5 and LAMP2A was induced by HCV infected and FFA treated Huh-7.5 cells.…”

Table_2_Phosphodiesterase 9A Inhibition Facilitates Corticostriatal Transmission in Wild-Type and Transgenic Rats That Model Huntington’s Disease.pdf by Shreaya Chakroborty (292318)

“…Acute systemic administration of the PDE9A inhibitor PF-04447943 significantly decreased the onset latency of cortically-evoked spikes in MSNs recorded in WT and TG5 rats. …”