Development of a Parallel Reaction Monitoring-MS Method To Quantify IGF Proteins in Dogs and a Case of Nonislet Cell Tumor Hypoglycemia by Alberto Valdés (1740604)

“…The method possesses good linearity and repeatability and has been used to evaluate the IGF-system in a dog with NICTH syndrome. In this dog, the levels of big IGF-II decreased by 80% and the levels of IGF-I and IGFBP-3 increased approximately 20- and 4-times, respectively, after removal of the tumor.…”

Phosphoenolpyruvate Carboxykinase, a Key Enzyme That Controls Blood Glucose, Is a Target of Retinoic Acid Receptor-Related Orphan Receptor α by Hiroshi Matsuoka (797627)

“…In addition, we show that suppression of RORα by siRNA significantly decreased PEPCK transcription. Finally, we found that a RORα antagonist inhibits hepatic gluconeogenesis in an <i>in vitro</i> glucose production assay. …”

Video_1_Case report: Immune remission from generalized myasthenia gravis in a dog with a thymoma and cholangiocellular carcinoma.MOV by Thomas Mignan (14805745)

“…<p>A 9-year-old male neutered Cockapoo was presented with an acute and progressive history of exercise induced weakness involving all limbs, and bilateral decreased ability to blink. …”

DataSheet_1_A Testis-Specific Long Noncoding RNA, Start, Is a Regulator of Steroidogenesis in Mouse Leydig Cells.pdf by Kai Otsuka (10507952)

“…Additionally, we observed a reduced number of Leydig cells at 8 days postpartum. …”

Structural and Magnetic Studies of a New Co(II) Thiocyanato Coordination Polymer Showing Slow Magnetic Relaxations and a Metamagnetic Transition by Susanne Wöhlert (1762705)

“…Magnetic relaxations, which were observed in the antiferromagnetic state, are retained at the metamagnetic transition. With decreasing field <b>3</b> remains in a state, in which except of the faster magnetic relaxation process in single chains also a slower process coexists resulting in the appearance of a magnetic hysteresis loop.…”

Table_1_Nutritional management of glycogen storage disease type III: a case report and a critical appraisal of the literature.docx by Elena Massimino (15457904)

“…CHO was mainly represented by high-fiber, low glycemic index food, and fat consisted prevalently of mono and polyunsaturated fatty acids. After a 2-year follow-up, all biomarkers of muscle and heart damage markedly decreased (by 50–75%), glucose levels remained within the normal range and lipid profile was unchanged. …”

Development of a Parallel Reaction Monitoring-MS Method To Quantify IGF Proteins in Dogs and a Case of Nonislet Cell Tumor Hypoglycemia by Alberto Valdés (1740604)

“…The method possesses good linearity and repeatability and has been used to evaluate the IGF-system in a dog with NICTH syndrome. In this dog, the levels of big IGF-II decreased by 80% and the levels of IGF-I and IGFBP-3 increased approximately 20- and 4-times, respectively, after removal of the tumor.…”

DataSheet_1_A Testis-Specific Long Noncoding RNA, Start, Is a Regulator of Steroidogenesis in Mouse Leydig Cells.pdf by Kai Otsuka (10507952)

“…Additionally, we observed a reduced number of Leydig cells at 8 days postpartum. …”

Structural and Magnetic Studies of a New Co(II) Thiocyanato Coordination Polymer Showing Slow Magnetic Relaxations and a Metamagnetic Transition by Susanne Wöhlert (1762705)

“…Magnetic relaxations, which were observed in the antiferromagnetic state, are retained at the metamagnetic transition. With decreasing field <b>3</b> remains in a state, in which except of the faster magnetic relaxation process in single chains also a slower process coexists resulting in the appearance of a magnetic hysteresis loop.…”

Deconvolution shows a strong effect of cell subtype proportions on gene expression variation in a study of blood leukocytes from asthmatics. by Yu Kong (487122)

“…(c) Looking into why the cell subtypes were so influential in altering gene expression, we find the proportions of two cell types to be significantly different in patients with severe asthma, an increased proportion of neutrophils (p = 0.021, Mann-Whitney test) and a decreased proportion of CD8+ T cells (p = 0.072, Mann-Whitney test). …”

Description of a minimally invasive technique with a modified instrument for the osteosynthesis of proximal femoral fractures using the standard DHS and case series by RICARDO RAMON CAMACHO IRIGOYEN (10459694)

“…Results: minimally invasive technique with a modified instrument using the standard DHS device can reduce bleeding, it decreases soft tissue injuries, surgical time, and hospital stay, as any other MIPO procedures. …”

Development of a Parallel Reaction Monitoring-MS Method To Quantify IGF Proteins in Dogs and a Case of Nonislet Cell Tumor Hypoglycemia by Alberto Valdés (1740604)

“…The method possesses good linearity and repeatability and has been used to evaluate the IGF-system in a dog with NICTH syndrome. In this dog, the levels of big IGF-II decreased by 80% and the levels of IGF-I and IGFBP-3 increased approximately 20- and 4-times, respectively, after removal of the tumor.…”

Progression of Osteosarcoma from a Non-Metastatic to a Metastatic Phenotype Is Causally Associated with Activation of an Autocrine and Paracrine uPA Axis by Liliana Endo-Munoz (789643)

“…Silencing of <i>uPAR</i> in metastatic OS cells abrogated the migratory response to uPA <i>in vitro</i> and decreased metastasis <i>in vivo</i>. Finally, a novel small-molecule inhibitor of uPA significantly (<i>P</i> = 0.0004) inhibited metastasis in an orthotopic mouse model of OS. …”

A Skin Care Program to Prevent Skin Problems due to Diabetes Devices in Children and Adolescents: A Cluster-Controlled Intervention Study by Anna Korsgaard Berg (16504675)

“…A total of 170 children and adolescents with type 1 diabetes were included and assigned either to the intervention group (n=112) or the control group (n=58). …”

Subcellular localization of proHNP processing. by Andreas Glenthøj (156936)

Data_Sheet_1_Weather Conditions and COVID-19 Incidence in a Cold Climate: A Time-Series Study in Finland.pdf by Behzad Heibati (8673855)

“…</p><p>Results: The incidence rate of COVID-19 gradually increased until a peak around April 6 and then decreased. There were no associations between daily temperature and incidence rate of COVID-19. …”

Image_3_A rare case of multiple paragangliomas in the head and neck, retroperitoneum and duodenum: A case report and review of the literature.jpeg by Shin Kawanabe (14368194)

“…A 40-year-old man complained right-ear hearing loss, and an intracranial tumor was suspected. …”

Supplementary file 1_A risk prediction model of spontaneous miscarriage in women with threatened miscarriage: a prospective cohort study.docx by Chee Wai Ku (5722886)

“…Introduction<p>This study aims to develop a holistic risk prediction triage tool for women with threatened miscarriage by integrating clinical, biochemical, and radiological factors. …”

A Genome-Scale DNA Repair RNAi Screen Identifies SPG48 as a Novel Gene Associated with Hereditary Spastic Paraplegia by Mikołaj Słabicki (246635)

“…We report 61 genes that influenced the frequency of HR-DSBR and characterize in detail one of the genes that decreased the frequency of HR-DSBR. We show that the gene KIAA0415 encodes a putative helicase that interacts with SPG11 and SPG15, two proteins mutated in hereditary spastic paraplegia (HSP). …”

NleC, a Type III Secretion Protease, Compromises NF-κB Activation by Targeting p65/RelA by Hilo Yen (235104)

“…In agreement, our present results showed that NleC was also required to inhibit inflammation. We found that NleC is a zinc protease that disrupts NF-κB activation by the direct cleavage of NF-κB's p65 subunit in the cytoplasm, thereby decreasing the available p65 and reducing the total nuclear entry of active p65. …”